An Efficient and Green Synthesis of Quinoxaline and Pyridopyrazine Derivatives Using Maghemite Nanoparticles Supported Ascorbic Acid

A new magnetically catalyst was synthesized by the immobilization of Ascorbic acid vitamin C on the surface of γ-Fe2O3 nanoparticles under ultrasonic agitation. The high catalytic efficiency of γ-Fe2O3@AA as a reusable organocatalyst in the synthesis of a wide variety of quinoxaline derivatives under mild eco-friendly conditions was exploited. Desired yields of heterocyclic compounds were obtained in the present method employing ethanol as an eco-friendly solvent under mild conditions. This novel magnetic catalyst could be easily separated from the reaction mixture by a magnetic bar and recovered at least five times without intense loss of its activity. Catalyst characterization was performed by using FT-IR, XRD, VSM and TEM.