Therapeutic effect of aerobic training on bone remodeling markers in sedentary cigarette males

Alkaline phosphatase and osteocalcin are bone remodeling markers. So that, increased their level is associated with bone formation. On the other hand, continued cigarette smoke is associated with the change in bone remodeling indexes. The present study aimed to assess the effect of 3 months aerobic training on alkaline phosphatase (ALP) and osteocalcin as bone remodeling markers in smoker males.

Thirty two sedentary age-matched (42 ± 2 years of old) males’ cigarette smokers were recruited in this study by accessible sampling and were randomly divided into experimental (n = 16) and control (n = 16) groups. The experimental group performed 12 weeks of aerobic exercise (3 days per week / 60-80 % of maximum heart rate) and control subjects did not exercise training. Pre and post training of anthropometrical markers, fating serum osteocalcin and ALP were measured in 2 groups. The ANKOVA test was used to evaluate the statistical significance of the changes. The change less than 0.05 were considered significant.

Significant decreases were observed in anthropometrical markers by aerobic training in exercise group (p < 0.05). Aerobic training induced significant increase in serum osteocalcin (p = 0.011) and ALP (p = 0.019) in experimental group, but these variables did not change in control group (p > 0.05)

long term aerobic training in presence continued cigarette smoking can be improved bone formation in smoker males.