Effects of 8 Weeks Aerobic Exercise Training on Plasma Levels of Pentraxin3 and C-Reactive Protein in Diabetic and Non-Diabetic Coronary Artery Disease Patients after Revascularization Interventions

The aim of this study was to investigate effects of aerobic exercise on plasma pentraxin-3 and C-reactive protein in diabetic and non-diabetic coronary artery disease (CAD) patients after revascularization interventions.59 male with CAD participate in our study and dedicated in intervention group (IG, n=29, weight: 76.58±11.25 Kg, age: 58.65±6.75 years, Diabetic/nondiabetic:14.15) and control group (CG, n= 30, weight: 76.13±14.79 Kg, age: 58.33±7.21, Diabetic/nondiabetic:15.15). Patients in IG performed 8 weeks aerobic exercise at 70 % of maximum heart rate, 3-4 times a week each session 60 min supervised by medical staff, CG has no physical activity program. Blood was drawn before and after 8 weeks to measure plasma levels of pentraxin 3(PTX3) and C-reactive protein (CRP). The analysis of variance (ANOVA) was used to compare pre-tests, post-tests were analyzed by using analysis of covariance (ANCOVA) with control of pre-tests value in P0.05). Aerobic exercise training can decrease plasma levels of PTX3 and CRP in CAD patients, aerobic exercise was more beneficial in non-diabetic than diabetic CAD patients.