Comparative Antioxidant Activities and Polyphenolic Content of Marine actinomycetes from Deylam nearshore sediments

Antioxidant used for chronic disease as treatment and for repalcing artificial antioxidant with natural antioxidant; To investigate antioxidant activity, we used marine actinomycetes as an important resources of bioactive compounds.. In this study, for phylogenetic analysis of 15 marine actinomycetes isolated from Deylam intertidal sediments, 16S rDNA sequences were used. In addition, the total phenolic content (TPC) was determined with the Folin-Ciocalteu’s reagent using gallic acid as a standard and the results were expressed as mM of gallic acid. Then, the antioxidant potential of the extracts was determined by analytical methods, ferric reducing antioxidants power (FRAP). The antioxidant potential of the crude extracts exhibited strong ferric reducing power activity at 517nm and the reducing power activity was strongly correlated with the total phenolics content of the isolates. Among the tested isolates, AHA1 (1419 µM) and AMJ1 (608.8 ) showed the hieghest and lowest total phenolic content, respectivly. Moreover AHA3 and AMJ5 (230.66 and 75.57µM) showed the highest and lowest reducing power, respectivly. These strains showed acceptable antioxidant activity and could be good candidates for more studies as nature resources of pharmaceutical antioxidant compound.