Tribromo melamine (TBM) as an efficient and inexpensive catalyst for the one-pot synthesis of benzimidazoles and benzoxazole derivatives

In this work, a simple and facile method for the preparation of tribromo melamine (TBM or melamine‐Br3) as an environmentally friendly homogeneous catalyst is described as it is used for the one-pot synthesis of benzimidazoles and benzoxazole derivatives via condensation reactions between aromatic aldehydes and ortho‐phenylenediamine or ortho‐aminophenol in aqueous media conditions. This green method offers significant advantages in terms of its simplicity, high catalytic efficiency, good to excellent product yields, use of ethanol as a green solvent, mild conditions, eco-friendly, and in acceptable reaction times.