Study of serum heat shock protein-27, adenosine deaminase, homocysteine and lipid profiles in bovine leptospirosis in Kurdistan province

The aim of this study was to investigate changes of serum parameters such as adenosine deaminase (ADA), heat shock protein-27 (HSP-27), homocysteine (Hcy) and lipid profiles (LDL,HDL,VLDL and Triglyceride) in bovine leptospirosis. After diagnosis of acute leptospirosis in cattle, blood samples were collected from 12 cases of bovine leptospirosis and 12 healthy samples via jugular vein and all parameters along with zinc (Zn2+) were measured. The results denoted a significant increase in Hcy, HSP-27, TG, VLDL, along with a significant decrease in HDL-C, ADA, LDL-C and zinc (Zn2+) in patients compared to healthy ones (p≤0.01). Based on the results, the listed parameters may be used in the management of bovine leptospirosis.