The Effect of 8 Weeks of Aerobic Exercise on c-Reactive Protein and Lipid Profile in Men with Colorectal Cancer

The main aim of this study was to investigate the effect of 8 weeks of aerobic exercise on C-reactive protein and lipid profile in men with colorectal cancer.27 male patients with colorectal cancer (mean age 51.56±11.28 years, height 1.71±0.07 m, weight 69.69±12.03 kg and body mass index 23.67±3.67 kg.m-2) were selected as the subjects. Subjects were divided into two groups: experimental (n=15) and control (n=12). At the beginning of the study, they were asked to complete Physical Activity Readiness Questionnaire (PAR-Q). The exercise program included 8 weeks of aerobic exercise, 3 sessions per week, 45 minutes per session and was performed with an intensity of 50-60% of target heart rate. Descriptive statistics were used to describe data such as mean and standard deviation and analysis of covariance was used to statistically analyze the data (α≤0.05). The results showed that 8 weeks of aerobic exercise had a significant effect on CRP (F=99.251 and P=0.000), BMI (F=11.25 and P=0.02), cholesterol (F=6.95 and P=0.015) and VO2peak (F=16.56, P=0.02). However, aerobic exercise had no significant effect on LDL, HDL and TG (P≥0.05). In conclusion, 8 weeks of aerobic exercise with moderate intensity can reduce CRP and cholesterol and increase VO2peak in men with colorectal cancer.