Is Hemoperfusion a Beneficial Treatment Option in COVID-19?

This review has been performed in the summer of 2020 by reviewing recent articles from the PubMed database. The study has been focused on viral infections similar to COVID-19 in terms of treatment options and the benefits of Hemoperfusion in these patients. COVID-19 is highly contagious with respiratory manifestations mainly. Lack of accurate treatment alongside the blatant mortality rate of the disease represents the urgency to achieve an efficient treatment to control this viral infection. Recent researches on the respiratory viral infections especially by coronaviridae (SARS, MERS, Coronavirus) has been revealed the major role of pro-inflammatory cytokines released in the blood, result in forming a cytokine storm syndrome leading to severe sepsis, septic shock, and finally to death. In several case reports, improvements in respiratory manifestations and SPO2 levels after blood purification from cytokines by Hemoperfusion has been demonstrated. Occurrence of adverse effects of hemoperfusion such as bleeding tendencies and hypotension have been limited its routine usage. In conclusion concerning the correctness of the hypothesis:" Is Hemoperfusion beneficial in COVID-19 treatment?" we have to affirm that despite optimistic reports, yet more investigations have to be done for definite judgment .