Effects of exposure to endosulfan subcutaneous doses on serum biochemical factors in (Danio rerio)

Many pesticides are introduced into aquatic ecosystems after use in agriculture, and since then they act as environmental pollutants. Fish biochemistry parameters are one of the most common factors influencing infection. In this study, the effects of subcutaneous doses of endosulfan venom (16, 32 and 64 μg / L) on serum biochemical parameters of Danio rerio were evaluated after 1, 2, 7 and 14 days.  The activity of alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, cholesterol, glucose showed a significant increase compared to control treatment (P≤0.05). Albumin activity also showed a significant decrease (P≥0 / 50) compared to control treatment. Protein activity on the first day of exposure to endosulfan was significantly increased (P≤0.05) in treatments, but no significant difference was observed on days 2, 7 and 14. In general, the long-term exposure to endosulfan subcutaneous doses causes biochemical changes in the blood of fish in the bloodstream. Therefore, biochemical factors can be suggested as a simple and suitable tool for assessing the effects of toxins on fish.