Blood pressure and heart rate during adaptation in ICR male mice

The blood pressure in male mice were measured at 16h, and 14, 28, 40 days after adaptation, where the standard was six days after shipping in ICR male mice. The experimental group was delivered overnight, for period of 16 hr. After 16hr from transport, the blood pressure was significantly higher than 14 and 40 days. Furthermore, 28 days after shipping, we recorded mid hypertension in ICR male mice. Systolic blood using the tail-cuff method, mice had significant mild high blood pressure. Experimental group adapted for 14 days after shipment, second for 28 days after transportation, and third until 40 days after transportation. Systolic blood pressure in the experiment group was 135±0.8mm Hg one week after delivery. Because this was far greater than previously reported for this strain, acclimatization took longer. Systolic blood pressure was measured 40 days after shipment was 120±0.03mm Hg. Throughout this time, heart rate also dropped from 531±0.5 in the experimental group to 380±0.2bpm in 40 days(P<0.05). Systolic blood pressure in the two control groups was also lower than in the experiment group 14 and 28 days after shipment.