Vision‑Related Quality of Life in Patients with Inherited Retinal Dystrophies
To evaluate the effect of inherited retinal dystrophies(IRDs) on vision‑related quality of life (VRQoL) among IRDs’ patients in Iran.
This cross‑sectional study was conducted on 192 patients with different types of IRDs who were randomly selected from registered patients in the Iranian National Registry for Inherited Retinal Dystrophy (IRDReg®). All ophthalmic findings were collected based on the recorded data in IRDReg®. Moreover, the eligible participants were interviewed to fill out the National Eye Institute Visual Functioning Questionnaire‑25 (NEI VFQ‑25) to assess their VRQoL. Ordinal logistic regression was used to evaluate the possible association of the different clinical and nonclinical factors such as demographic information, socioeconomic status, and visual function with VRQoL.
The overall mean of a composite score of VRQoL was 45. All subscales obtained from the NEI VFQ‑25 questionnaire except general health, mental health, and ocular pain had a significant negative correlation with logMAR best corrected visual acuity (BCVA) and near visual acuity variables. There was a statistically significant relationship between VRQoL and factors like age (odds ratio [OR] = 0.91, 95% confidence interval [CI]: 0.87–0.94), employment status (OR = 1.37, 95% CI: 1.05–4.74), logMAR BCVA (OR = 0.31, 95% CI: 0.19–0.49) and normal color vision (OR = 1.92, 95% CI: 1.74–5.01).
The VRQoL of patients with IRDs in this study was low. BCVA could be an indicator to show VRQoL.
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