The cytotoxic effect of Spirulina extract on gastric and prostate cancer cell lines

The AGS cell line contains gastric cancer cells, which are among the most common cancers in the world. The DU145 cell line also includes prostate cancer cells, the second leading cause of death in men after lung cancer. This study was designed to assess the cytotoxicity of spirulina extract on AGS and DU145 cell lines. In this in vitro trial, cell lines AGS and DU145 were used. Gastric and prostate cancer cell lines were prepared and cultured from the Iranian Center for Biological and Genetic Resources. The cells were divided into treatment and control groups. The effect of spirulina extract on the treated group was determined using the MTT method. According to MTT results, Spirulina extract has anti-cancer activity and more than 50% reduction in cell density against AGS and DU145 cell lines; While it did not show any significant effect on healthy cells (P< 0.05). The results of this study indicate that Spirulina extract has a good potential to control cancer cells.