Changes in serum levels of interleukin 15 and lipid profile following the intervention of moderate intensity aerobic exercise in middle-aged men with metabolic syndrome

Glucose absorption improves in the human body by IL-15 and related metabolic disorders in patients with metabolic syndrome (MS) may be affected by aerobic exercise. The aim of this study was to investigate the effect of an aerobic exercise session on interleukin-15 levels and metabolic risk factors.

In this study 20 men with MS were selected voluntarily and randomly divided into two control (n=10) and aerobic exercise (n=10) groups. The exercise program included 12weeks of aerobic exercise with 3 sessions per week and each session consisted of 45 minutes of exercise with an intensity of 60-70% of the maximal heart rate. Blood samples were taken from the subjects before and after the intervention of the exercise program to measure blood variables including IL-15, HDL, LDL, TG, TC, and blood glucose. The data were analyzed by independent and dependent sample t-tests at a significance level of 0.05.

There is a significant difference between the two groups in all variables. In the exercise group, in the post-test compared to the pre-test, the values of IL-15, HDL, and VO2peak significantly increased (P<0.05).  The values of BW, BMI, WC, MBP, TC, TG, LDL, FBS, and insulin resistance index had a significant decrease (P<0.05).

12 weeks of moderate- intensity aerobic exercise program can be suggested as a non-drug method to control metabolic risk factors in patients with metabolic syndrome.