Biosynthesized Co-ZnO Nanorods against breast cancer cells

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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:

Through a successful attempt, the extract of Prosopis fracta was exerted for the green and simple production of pure and 3% cobalt doped zinc oxide Co-ZnO) nanorods (NRs), which were configured in the following through the analytical results of XRD, FESEM, and EDX procedures. The appearance of finely doped cobalt throughout the construction of zinc oxide was approved by the data of XRD and EDX. Considering how the length and diameter of pure ZnO Nanorods were determined by the FESEM process to be 500 ± 0.2 nm and 100 ± 5 nm, the doping process of cobalt into ZnO caused an enlargement respecting the doped nanorods length as well as diameter. We examined toxicity of nanorods towards breast cancer MCF-7 by the employment of WST-1 trial. In contrast to results of pure nanorods, the doped nanorods were abled to induce a stronger toxicity on MCF-7 cells and therefore, it can be indicated that the conduction of doping process on ZnO nanostructure resulted in intensifying its inhibitory impact towards MCF-7 cells.

Language:
English
Published:
Nanomedicine Research Journal, Volume:8 Issue: 2, Spring 2023
Pages:
141 to 148
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