Measurement of cardiac troponin I and troponin T in patients with acute myocardial infarction

Acute myocardial infarction (AMI) is one of the most common diseases today. One of the important issues which are under attention of searchers is to diagnose AMI accurately using paraclinic methods. The aim of this study was to determine the level of two important biochemical markers of AMI cardiac troponin I and T. This study was a descriptive-analytic study, which was performed on 100 patients in whom-according to criteria of WHO and references-diagnosing of AMI is definite, in second day of admission in CCU, cardiac markers including troponin I using qualitative immunochromatography assay and cardiac troponin T using third generation cTnT detection assay (CARDIAC) and also total creatine kinase (CK) was measured and record for patients. This information was recorded in a special data sheet and than analyzed by using SPSS, Chi-Square and t-test. Mean age of patients was 59.73±12.57. 38 patients were women and 62 of them were men. 83 of patients (83%) had positive troponin I, 97 (97%) had values of troponin T more than 0.1 mg/ml (indicating AMI) and also 93 patients (93%) had total CK value more than normal. Troponin T is a more sensitive marker for diagnosis of AMI comparing with other cardiac markers of AMI in 24 h after AMI.