The study of glycolysis enzymes in thalasemia

Thalassemia is the name of a group of genetic blood disorders. Thalassemia is an inherited disease of the red blood cells, classified as a hemoglobinopathy. In the research patients were selected major thalassemia for aldolase, hexokinase enzymes activity level, Serum Ferritin arterial blood oxygen were measured In the experimental research, 50 patients were selected among 700 patients with major thalassemia who were treated in Sayedolshohada hospital in Isfahan. Serum Ferritin, arterial blood oxygen and Aldolase –Hexokinase enzymes activity level were measured in these patients. A comparison was performed between mean level of serum ferritin, mean level of arterial blood oxygen, and activity level of Aldolase- Hexokinase enzymes. Mean level of Serum Ferrtin in 50 patients with major Thalasemia 237 µg/ml was made. According to the findings the increase of Aldolase- Hexokinase is increase with the increase of Serum Ferritin level.