STUDY OF THE SERUM AND URINE CALCIUM IN PATIENTS WITH URINARY STONE IN FORMATION KHORASAN, IRAN

Background and Urinary stones are the third most common cause of urinary tract disorders and hypercalciuria is reported in 30% to 55% of patients. Therefore, this study is intended to study the serum and urine calcium in patients with urinary stone formation in khorasan, Iran. Methods and Materials: This descriptive-analytical study was conducted from 2003 summer through 2005 spring on 100 patients (case) and 51 non-patients (control). Relevant data were collected through questionnaire, serum calcium measurement (morning blood sampling) and urinary calcium measurement (24-hour urine collection). Hypercalciuria was observed in 9% of the case group and 2% of the control group. No significant difference was observed in the urinary calcium of the two groups. (2.23±1.07 vs. 2.13±1.10 mg per kg body weight/24 hours). Hypocalcaemia was detected in one of the cases but in the control group, nobody was so. Also, no significant differences were observed in the serum calcium of the two groups (9.07±0.68 vs. 9.13±0.64 mg/dl). Compared with references and recent publication, regional hypercaliuria is obviously lower and it is inferred that empirical therapy to prevent stone formation by reducing calcium has no therapeutic role. There seems no need for routine examination of serum calcium.