Cloverleaf Skull Syndrome Associated with Cleft Palate

To report a case of cloverleaf skull syndrome with cleft palate.

We report a 20-day-old boy with cloverleaf-shaped skull deformity, very constricted cranium and prominent temporal bones associated with severe proptosis, maked lid retraction, conjunctival chemosis, exposure keratitis, corneal opacity and cleft palate. CT-scan dislosed fusion of the coronal, sagittal and lambdoidal skull sutures with shallow orbits. To control the exposure keratitis, bilateral tarsorrhaphy was performed temporarily and the patient was referred to the neurosurgery service.

To the best of our knowledge this is the first report on the association of cleft palate with cloverleaf skull syndrome. After performing preliminary measures for preservation of the cornea, patients should be referred to neurosurgeons or plastic surgeons.