Angioid Streaks and Skin Lesions in a Patient with β Thalassemia: A Case Report

To report concomitant angioid streaks and skin lesions in a patient with β thalassemia.Patient and A 47-year-old female, a known case of  thalassemia, presented with gradual decrease of vision in her right eye. On indirect ophthalmoscopy of both eyes, angioid streaks were detected. On fluorescencin angiography, hyperfluorescence of streaks without signs of choroidal neovascularization were seen. Skin lesions (small yellowish papules) similar to pseudoxanthoma elasticum were detected on the neck and antecubital area. Both angioid streaks and skin lesions are manifestations of elastic tissue abnormality which may be the result of inflammatory and oxidative reactions in this hemoglobinopathy.