Clinical manifestations of Burger's disease and its related factors in Taleghani Hospital, Tehran, 2000-01

Burger's disease has various presentations. During the present study we have determined the clinical manifestations of Burger's disease in a group of patients referring to Taleghani hospital in 2000-01. It was a descriptive study. Diagnosis was confirmed in accordance with clinical manifestations and angiography. Patients’ clinical signs and symptoms as well as other demographic data were recorded. 42 patients with definite diagnosis of Burger's disease and the mean age of 35.9±2 years were included. All were male and smoker. 71% had addiction and 54.8% had previous history of smoking for more than 10-20 years. Poor health status was reported in 69%. Clinical manifestations were: Resting pain (81%), ischemic ulcer, intermittent claudication, thrombophlebitis and upper limb’s pain. Our patients’ clinical signs and symptoms have differed with reports of western societies. Poor socioeconomic and health status are the major risk factors. Further studies are highly recommended.