A comparison of fluoride uptake by sound enamel following application of sodium fluoride mouthrinses and APF gels produced in Iran with standardized foreign samples

The goal of this investigation is to compare the extent of fluoride uptake by sound enamel following application of two commercial mouthrinses containing sodium fluoride (0.2%) and a topical gel containing APF (1.23%) produced in Iran with those of foreign standardized ones. Sixty extracted premolars were used. Each tooth was divided into two lingual and buccal halves, one half as control, the other one as experimental. Enamel biopsy technique (two- step acid etching) was used to determine the concentration of fluoride and calcium in each sample. For data comparison and fluoride uptake estimation, the depths of layers with the use of linear regression analysis were standardized to 25 and 50um. The analysis showed that in Iranian mouthrinse no. 1, there is linear correlation between fluoride concentration and enamel depth, in both control and experimental group at the first and second layers, while, in other groups, this correlation was observed just at the first layer (superficial enamel layer). The greatest fluoride uptake was seen at Iranian mouthrinse no.2 and the least was seen at foreign mouthrinse no. 3. From among two APF gels, the greatest uptake was observed at gel no. 1 (Iranian). The results showed that all three Iranian products increase fluoride content of enamel, moreover the level of fluoride uptake, while applying Iranian products, in comparison with foreign ones, shows considerable increase.