L-Carnitine Level in Seminal Plasma of Fertile and Infertile Men

To determine any correlation between infertility and semen quality with concentrations of L-carnitine in human seminal plasma. This case-control study performed in Fatemieh Hospital in Hamadan, Iran. Seminal plasma of 72 infertile men and 80 men with proved fertility as a control group was investigated and L-car nitine level was determined using UV enzymatic test at 340 nm. The concentration of L-carnitine was significantly lower in the infertile group compared with con trol group (80.59?56.43 mg/l versus 108.43?42.26 mg/l; P= 0.0009). There was also a statistically signifi cant positive correlation between seminal plasma L-carnitine concentration, total sperm count, and the percentage of motile sperm (P= 0.0009, and P= 0.0000, respectively). These finding suggest that the determination of seminal plasma L-carnitine level may be a useful test in evaluation of male infertility.