Investigation of Interaction Between DNA and AOT-Ionic Reverse Micelles in DNA Nano-Encapsulation Process

Reverse micelles are nano-size systems were used in different processes such as, separations and kinetics. Also, these systems are suitable for modeling of bio-membrane processes in laboratory, invivo conditions. In this study, the nano-encapsulation of DNA macromolecule in an anionic reverse micellar system, AOT, and interaction between species were investigated. For this purpose, the UV and circular dichroism spectra were used to show DNA solubilization, nano-encapsulation, and interaction between entrapped DNA and reverse micelles, respectively. The experimental results showed the capability of anionic reverse micellar system for DNA nano-encapsulation and molecular condensation.