Association between ear lobe crease and cerebrovascular accidents

Cerebrovascular accidents (CVA) are the third and second common cause of death and morbidity in the world, respectively. Since high levels of serum lipids and atherosclerosis are one the risk factors of CVA, and also there are some reports about relation between atherosclerosis and earlobe crease (ELC), the present study was performed to verify any association between ELC and CVA. This study was designed as a case-control study. 55 patients with CVA (case group) and 55 patients without CVA (control group) were selected, and then presence of ELC and serum levels of cholesterol, LDL, HDL were measured in both control and case groups. The prevalence of ELC in CVA patients was more than without CVA (%74.1 vs. %26.8- p<0.001). Mean level of Cholesterol and LDL were more in patients with CVA than without CVA (p<0.001). Also, mean level of HDL in CVA group was less than control group (p<0.001). Mean level of cholesterol and LDL were more and mean level of HDL was less in patients with ELC than patients without ELC (p<0.001) The prevalence of ELC in patients with CVA is more than in patients without CVA (OR: 7.81). Mean level of serum lipids in these patients were more than patients without CVA. CVA in patients with ELC is 7.81 times more common than without ELC. In due attention to high prevalence of ELC in patients with CVA, it seems ELC must be evaluated as a risk factor