The Relation of Cardiovascular Risk Factors and Electrocardiographic Change; Isfahan Healthy Heart Program

Cardiovascular disease (CVD) is the leading cause of mortality worldwide. Various studies show meaningful relation between ECG change in the rest and CVD mortality. Present study was performed to consider the relation between ECG and CVD risk factors in Iranian community. This cross-sectional study was performed on 3343 subjects aged ≥ 35 years from three provincial cities of Isfahan, Arak, and Najafabad. Questionnaire including questions on demographic and lifestyle information, as well as weight, height, blood pressure, hip and waist circumference measurement was completed. Laboratory tests including total cholesterol (TC), LDL, HDL, triglycerides (TG) and fasting serum glucose were measured as well. Ischemic criteria of ECG included minor and major changes in ST segment, T wave, conductive disorders, blocks and arrhythmia. Collected data were analysed using SPSS15 software. Ischemic changes in women were 1.5 times more than men (P < 0.05). Mean age of Ischemic group was 5 years more than non-Ischemic group. Comparison of lifestyle variables indicated that physical activity reverse to nutrient index, was significantly more in non-ischemic individuals compare to ischemic individuals. Smoking show a significant difference between two groups too (P < 0.05). Anthropometric variables including body mass index (BMI), hip and waist circumference and diabetic and systolic blood pressure in Ischemic group were significantly higher (P < 0.05). Biochemical factors including TC, HDL-C, LDL-C in ischemic group were significantly higher than non-ischemic group (P < 0.05). Considering of ischemic change in healthy individual with unhealthy life style or with risk factors, these points should be considered in evaluating of these individuals.