Correlation of HbA1c and Major Depressive Disorder in Type 2 Diabetic Patients

: To evaluate the relation between major depressions and glucose control index in type 2 diabetes mellitus.
MATERIALS AND METHODS: One- hundred thirty four patients with type 2 diabetes were enrolled in this study. Hamilton Rating Scale for Depression (HAM-D) and HbA1c were measured in patients. Linear mixed-model analysis was applied to determine the relation between HbA1c levels and depressive symptoms.
Groups of patients with and without depression were similar in age and BMI. Correlation analysis revealed no significant relationship between HAM-D scores and HbA1c level. Depressive scores were significantly higher in diabetic patients with hypertension (P = 0.0001) and on insulin treatment (P = 0.005). There was a significant positive relationship between HAM-D scores and disease duration. (P < 0.01).
The findings of this study showed that there was no significant association between the level of depressive symptoms and HbA1c in patients with type 2 diabetes.