Effects of Taranjebin on serum bilirubin in hyperbilirubinemic suckling rats

In the past, medi cinal herbs had enormous application in traditional medicine in Iran. At present, Taranjeb in a gum of Alhagi herb (Alhagi Mannifcr a) is used as a medi cal herb for trea tment of jaundice in infants. Th us, the purpose of present stud y was to investigate the possible therapeutic effects of Taru njcbi n on a scientific basis. Taranjebin solution was made by disso lving Taranjebin in distilled water and then filtered. Wistars offspri ng ra ts (body weight: 19-21 gr) wer e used. Animals were divided into fo ur groups: group one as a negative control, ot her thre e groups we re inj ected inet rap eritoneal (ip) aminolevulin ic acid (ALA) at a specific lime afte r bir th, which ca use s hyperbil irubinemia. Of these three groups, one group was used as a positive control, and the othe r two as experimental group received Taranjebin and distilled wat er by gavage, res pec tively. At different interval times blood samples were drawn and to tal bilirubin was mea sured. R esults sho wed th at afte r inj e ct ion of ALA, pl asm a biliru bin co ncen t rat io n incre ased significantly (P