Ocular Features in Marfan's Syndrome

To determine the prevalence of ocular manifestations in Marfan's syndrome. This cross-sectional study was performed on 43 patients referred to ophthalmology clinics of Yazd Medical University over 27 months. Common ocular manifestations of Marfan's syndrome including lens dislocation, corneal disorders, retinal conditions, glaucoma were evaluated. The study included 24 female (55.8%) and 19 male (44.2%) subjects with mean age of 26.23±7.5 (range 6-44) years. Thirty-nine patients had family history of Marfan's syndrome. The most common ocular signs included lens subluxation (76.7%), high myopia (41.9%), strabismus (27.9%), glaucoma (14.0%), flat cornea (11.6%) and retinal detachment (7%). Overall 14.0% of patients had previous ocular procedures including lensectomy, scleral buckling and squint repairing. The cardinal ocular features of Marfan's syndrome include lens ectopia, high myopia, squint, glaucoma and retinal detachment.