Effect of Acetic Acid and Ethanol on Growth and Life Span of Chinese Hamster Tumor Cells

This study investigates the antiproliferative activity of ethanol and acetic acid on tumoral cells C11-B11 from Chinese hamster. Different concentrations of ethanol (ET) and acetic acid (AA) were applied in two experiments: 0 – Control; 0.001% AA; 0.005% AA; 0.01% AA; 0.05% AA; 2% ET; 2% ET + 0.05% AA; 0.05% AA, 2% ET + 0.1% AA, 0.1% AA. Proliferation and growth of cells general and stationary life spans were determined. According to the results, some concentrations of ethanol and acetic acid can inhibit growth and proliferation of cancerous cells. 2% ET increased general and stationary life span by 1.33 and 1.49 respectively. The effect of 0.05% AA alone was the similar to combination of 0.05% AA with 2% E and fixed the cells. Life span Increasing in the culture medium could be applied to gerontology and is hypothesis for increasing life span in humans and animals. Since some concentrations of acetic acid and ethanol could eradicate cancerous cells, this approach could be applied in oncology too.