Greenlight Photoselective Vaporization of the Prostate (PVP) vs. Transurethral Resection of Prostate (TURP) for Benign Prostatic Hyperplasia (BPH)

Greenlight Photoselective Vaporization of the Prostate (PVP) is a minimally invasive method of treatment for clinical benign prostatic hyperplasia with fewer side effects. The aim of this study is evaluation of safety، effectiveness and cost effectiveness of PVP in compare of transurethral resection of prostate in Iran. A systematic search was done in Cochrane، TRIP database، MEDLINE، NHS EED، NIHR HTA، CRD، Health star database، ProQuest، Psycoinfo and Google Scholar to find randomized control trials، systematic reviews and HTA reports. The searched keywords were Green light laser (PVP or KTP) and prostate. The cost analysis was done by the prespective of social and providers. Complication rate in 12 included evidences ranged from 0-9. 3%. The complication rate of TUR-P was more than PVP. Changing in flow rate reducing residual urine، improving patient symptom and QOL and operative outcome Length of operation was varied from no significant to significant different in favor of TURP. Unit cost in both social and provider view، was significantly high in PVP in comparison of TURP. Increasing the number of patients did not change the cost analysis. PVP is a safe method for treatment of clinical BPH، but there is a lack of evidence for evaluation of effectiveness. Overall unit cost for PVP was significantly more than TURP for this reason this method has to use in very selective cases in limited centers.