Effects of Nanosilver Dressing on Wounds Created in Rats

Message:
Abstract:
Background
Nowadays dressing sterilization and management of wound infection costs a lot. Nanosilver is a nanotechnology product with antimicrobial property. It can improve efficiency, reduce cost and increase antibacterializing durability and performance of textiles. This study was performed to determine the efficacy of nanosilver dressing in wound recovery in rats.
Methods
In this experimental study, 10 rats were divided into 2 groups of 5. After anesthesia, superficial wounded of equal size were made on the shaved backs of all animals. The first group was dressed by nanosilver dressing while the second group was dressed by none nanosilver dressing. Then, wound areas were measured every 2 days for 12 days. Data was analyzed using analysis of variance (ANOVA).
Findings
The recovery period among the rats bandaged with nanosilver dressing was significantly shorter than the other group (P < 0.05). In addition, less side effects were observed in the group treated with nanosilver dressing.
Conclusion
According to our findings, nanosilver dressing can be effective in controlling superficial wound infection. Nanosilver dressing can also improve deep infections caused by thermal, chemical and electrical burns.
Language:
Persian
Published:
Journal Of Isfahan Medical School, Volume:29 Issue: 164, 2012
Page:
2
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