Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome: a case report

Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) syndrome is an auto-inflammatory bone and skin disorders that is presented by dermatological manifestation such as palmoplantar pustulosis, pustular psoriasis, psoriasis vulgarism, severe acne, and hidradenitis suppurativa and joints and bones inflammation such as sacroiliac joint and vertebra. In this case report, a 16-year-old boy is presented that is suffering from low back pain, conglobata acne on trunk and face, and hidradenitis supportive (Dissecting Cellulitis) on the scalp. Diagnosis was based on clinical findings and laboratory tests. Treatment conducted by non-steroidal anti-inflammatory drugs and orally administered Isotretinoin. Dramatic improvement in low back pain was reported by patient in a few days. In follow-up examination of the patient after discharge from Hospital, we detected improving acne follicles and hidradenitis suppurativa on the scalp in clinic of rheumatology.