Antimicrobial Photodynamic Therapy: An Effective Alternative Approach to Control Bacterial Infections

The purpose of this review was to evaluate the available literature for in vitro and in vivo effectiveness of antimicrobial Photodynamic therapy (aPDT) in the field of bacteriology.
A review of the relevant articles carried out in PubMed and Scopus to determine the efficiency of aPDT used in the reduction of microbial infection. Thirty-one relevant documents retrieved from PubMed, Scopus by inserting “antimicrobial photodynamic therapy” and “bacterial infection” and “photodynamic therapy” keywords.
According to different results, aPDT can be used as an adjuvant for the treatment of infectious diseases. The use of photosensitizer methylene blue, toluidine blue O (TBO), indocyanine green with light diode laser centered at (630±10 nm) and (650±10 nm) wavelengths have been shown to have significant results for the treatment of infectious diseases and bactericidal properties
These findings suggest that, aPDT can be an efficient method in the treatment of localized and superficial infections.