Comparing Vitamin D Serum Levels in Patients with Oral Lichen Planus and Healthy Subjects
Author(s):
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Statement of the Problem: Lichen planus disease is a chronic inflammatory lesion without a known etiology. Recent studies have indicated the role of vitamin D on immune system and proposed its anti-inflammatory effects.
Purpose
This study aimed to compare vitamin D serum levels in patients with oral lichen planus and healthy subjects.Materials And Method
In this case‒control study, 18 patients suffering from oral lichen planus referred to the Department of Oral Medicine, Tabriz Faculty of Dentistry were chosen as the case group and 18 healthy people were chosen as the control group. A 5-mL blood sample was taken from all subjects and the subjects vitamin D serum levels were assessed with a vitamin D total (25-hydroxy vitamin D) kit by employing the electrochemiluminescence technique. The results were analyzed and compared by using SPSS17 statistic software. pResults
The mean vitamin D level in serum of patients with oral lichen planus was 30.7±20.38ng/ml and in healthy subjects was 36.45± 15.33ng/ml, the difference was not statistically significant (p= 0.346).Conclusion
The difference between the level of vitamin D in the serum of patients suffering from oral lichen planus and healthy individuals was not significant.Keywords:
Lichen Planus , Oral , Vitamin D , Serum
Language:
English
Published:
Journal of Dentistry, Shiraz University of Medical Sciences, Volume:19 Issue: 3, Sep 2018
Pages:
212 to 216
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