Diurnal Salivary Cortisol following Mindfulness-Based Cognitive Therapy (MBCT) in Women with Breast Cancer: A pilot Study
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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background And Objectives
Cancer and its conventional treatments may bring about some psychological and health-related symptoms leading to unstable cortisol level. Since evidence has shown that mindfulness based approaches can be helpful to reduce cortisol level, we aimed at investigating the efficacy of mindfulness-based cognitive therapy (MBCT) on decreasing salivary cortisol level in the women with breast cancer.

Methods
in this one- group pretest posttest study, the women with early stage breast cancer were assessed to select eligible ones (N = 15). They were first trained for collecting salivary cortisol sample (before, after and follow-up) and then were asked to participate in MBCT, an eight-week session approach. Participants provided salivary samples in the morning (7: 30- 8:30), afternoon (1-3) and night (9-11). To measure cortisol, Cortisol Enzyme Immunoassay Kit was used. Analysis was performed on the data of 12 participants remained, using repeated measurement.

Results
the results of repeated measure ANOVA revealed that cortisol level of posttest (after 8-weeks of MBCT and follow-up period) in comparison with pretest was significantly reduced for morning and afternoon cortisol while it was not true for night cortisol. The post-treatment cortisol was not significantly correlated with age groups, education levels and socio-economic status using repeated measure ANCOVA.

Conclusion
Given that the women with breast cancer are at the high risk of psychological distresses and unstable cortisol level, we recommend mindfulness-based approaches esp. MBCT to health providers specifically those working with breast cancer patients.
Language:
English
Published:
Medical Laboratory Journal, Volume:12 Issue: 5, Sep-Oct 2018
Pages:
16 to 22
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