The Effect of Spirulina Supplementation and Combined Aerobic-Strength Training on Serum Homocysteine of Sedentary Females

The increasing rate of mortality due to cardiovascular disease has been reported in people with low physical activity worldwide.

The purpose of the present study was to investigate the effect of spirulina supplementation and combined aerobic-strength training on serum homocysteine of inactive females.

It was a semi experimental study with pre and post-test design. The subjects consisted of 37 sedentary women who participated voluntarily in the study and were randomly divided into supplement; training and supplement+training groups. Measuring the study variables including serum homocysteine and anthropometry variables were done in pre-test and posttest phases. The data were analyzed using paired t test and ANOVA.

The results suggested that spirulina supplementation and combined aerobic-strength training had a positive influence on serum homocysteine levels in sedentary women (P = 0.003, P = 0.04 respectively) with a greater influence by the combined effect of exercise and supplement (P = 0.001).

The results indicate that homocysteine as an independent cardiovascular disease risk factor in sedentary women can be modified by spirulina and combined strength and aerobic exercise