Acinetobacter baumannii Infection in the Neonatal Intensive Care Unit
Message:
Abstract:
Background
To perform a prospective case control study of blood stream infection to determine the infection rate of Acine tobac ter baumannii and the risk factors associated with mortality.
Methods
From February 2004 to January 2005, 579 consecutive episodes of blood stream infection were obtained at two neo na tal intensive care units Al Nasser and Al Shifa hospitals in Gaza City. Forty (6.9%) isolates of A. baumannii were ob tained from the neonates under 28 d. Most of the isolates (92%) were from hospitalized patients in the intensive care units.
Results
Community acquired infection was 8%. Sixty three percent of the patients were males. The isolates of A. bauman nii were resistant to commonly used antibiotics while being sensitive to meropenem (92.5%), imipenem (90%), chloram pheni col (80%), ciprofloxacin (75%), gentamicin (57.5%), ceftriaxone (50%), amikacin (37.5%), cefuroxime and ce fo taxime (35%). Over all crude mortality rate was 20% with much higher crude mortality among patients with noso co mial infec tion. Based on logistic regression, the following factors were statistically significant: weight < 1500g, age < 7 d, mean of hospitalization equal 20 days, antibiotic use, and mechanical ventilation, when compared to the control group (P< 0.05).
Conclusion
Infection rate of nosocomial blood stream infection was considerable and alarming in neonatal intensive care unit infants and associated with a significant excess length of NICU stay and a significant economic burden.
Language:
English
Published:
Iranian Journal of Public Health, Volume:37 Issue: 3, Autumn 2008
Page:
107
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