بیت الله علیپور

Polycystic ovary syndrome (PCOS) is a common endocrinopathy among women and insulin resistance is one of the clinical features in this syndrome which plays an important role in improvement of lipid disorders. Dietary glycemic index and glycemic load can affect blood lipid disorders. Because of limited studies in this field, this study was performed with aim to evaluate the relationship between dietary glycemic index/glycemic load and serum lipids level in women with PCOS.

This case-control study was conducted on 45 PCOS women and 45 healthy controls in Moheb Yas Women hospital of Tehran in 2016. Dietary intake was assessed using three 24-h recall questionnaires, and glycemic index and glycemic load were calculated by standard methods. Lipid profile was measured and insulin resistance was calculated by the formula. Anthropometric measurements were conducted in all participants. Data were analyzed by SPSS software (version 16), and Independent T-test and correlation test. P< 0.05 was considered statistically significant.

Mean of serum total cholesterol, insulin resistance and mean of glycemic index was significantly higher in the patients group than the control group (P<0.05). There was a significant relationship between glycemic load and insulin resistance, triglyceride and HDL-c in patients (r=0.388, r=0.401, r= -0.371, respectively (P<0.05). No significant relationship was found between glycemic index with biochemical markers in patients and controls (P>0.05).

Lifestyle modification like correct nutritional status and management of carbohydrate intake and reducing the dietary glycemic load may be effective in prevention or reducing the complications of disease such as lipid abnormalities.

Osteoarthritis is one of the ten debilitating diseases in developing countries. This study was designed to examine the effect of Burdock root tea on lipid profile and blood pressure in patient with knee osteoarthritis (OA).
This was a randomized one-way blinded 6- week clinical trial. Thirty-six patients (10 men and 26 women) aged 50-70 year-old with knee osteoarthritis referred to the physical medicine and rehabilitation department of the Tabriz University of Medical Sciences Hospitals, were selected for the study and divided into two groups randomly. For all individuals along the 42 days of study period, the same drug treatments including physiotherapy (20 an-hour sessions for both knees) and two lots of 500 mg acetaminophen twice a day and one glucosamine 500 mg once a day were considered. The intervention group received daily 3 cups of Burdock root tea Control group received 3 cups contain 150 cc boiled water daily. Venous blood samples were collected at baseline and after 6 weeks the intervention to measure lipid profile parameters and their ratios before and after the intervention. Systolic and Diastolic blood pressure were also measured and analyzed. Anthropometric measurements, physical activity levels and nutrients intake were evaluated before and after intervention. Differences between the two groups and among the each group were analyzed using independent t-test, Mann-Whitney U-test, analysis of covariance, paired sample t-test, Wilcoxon Signed Ranks Test, sign test, chi-square and McNemar test. SPSS 16 was used for statistical analysis.
A significant reduction in levels of total cholesterol, TC/HDL-C and LDL-C/HDL-C ratios, systolic, diastolic and mean systolic and diastolic blood pressure and a significant increase in HDL-C levels was observed in intervention group compared with the control group (p The results showed that Arctium lappa l. root tea consumption with reduction in blood pressure, levels of LDL-C, ratios of TC/HDL-C and LDL-C/HDL-C and increase in levels of HDL-C could control and improve lipid profile and blood pressure status in patient with knee osteoarthritis (OA). But yet, the mechanism of effects of hypolipidemic and decrease in blood pressure of Arctium lappa l. is not clear, so more studies are need in this field.

Background and Portulaca Oleracea grows in many areas of the world. This plant is called «Power food of the future» because of many factors. The purpose of this study was to review the nutritional value and efficacy of Portulaca Oleracea.
Material and In this review, search was performed of SID, PubMed and Google Scholar for the keywords including Purslane and Portulaca Oleracea during 1987- 2014, and the results were discussed.
Portulaca oleracea due to the existence of different nutritious ingredients like a variety of vitamins, minerals, essential fatty acids, flavonoids and antioxidants such as beta-carotene and glutathione is known as the universal panacea. In addition, because of these compounds it is used in the prevention and treatment of a variety of diseases in both traditional and modern medicine and is consumed as a part of the food industry and diet in many countries.
According to studies, it seems that the Portulaca oleracea can be considered as one of the most important nutrients in the future and used as a part of the diet of all age groups.

Today, the relationship between asthma and obesity in many studies is reviewed and weight control is used as a way for control of symptoms and severity of asthma along with other treatment protocol. Portulaca oleracea is consumed for weight loss in some countries. The experiment is designed to study the effect of Portulaca oleracea seeds on anthropometric measurements in asthmatic patients. In a randomized clinical trial, 59 patients with asthma disease divided to intervention (n=31) and control (n=28) groups. First group received asthma treatment and consisting 10g/day P. oleracea seeds in two doses in the morning (fasting) and before dinner with a glass of water for 8weeks. Participants in second group received only asthma treatment. At the beginning and end of the study, anthropometric measurements were measured on each subject. The anthropometric measurements including weight, body mass index and waist circumference indicated any significant differences between two groups after completion of the study (P˃0.05) but hip circumference and waist-to-hip ratio had significant decrease (P= 0.003) and increase in intervention group (P= 0.04), respectively. Consumption of Portulaca oleracea seeds influence on some anthropometric measurements likes hip circumference and waist-to-hip ratio in asthmatic patients. However, the effects of them on other anthropometric measurements need further investigations.

The effects of lentil sprouts (LS) on lipid profiles and FBS among overweight and obese patients with type 2 diabetes have not yet been examined. Considering the importance of legumes and cereal sprouts in traditional Iranian medicine, we conducted this trial to investigate the effects of LS on fasting blood glucose, and the atherogenic index of plasma (AIP), in overweight and obese patients with type 2 diabetes.

Thirty-nine patients were randomly divided into two groups. For all individuals throughout the 8 weeks of the study period, the same drug treatment was given, with the intervention group patients consuming 60 g lentil sprouts in addition daily. Total cholesterol, triglycerides (TG), low-density lipoprotein (LDL-C), high density lipoprotein (HDL-C), fasting blood glucose (FBS) and atherogenic index of plasma (AIP) were measured at baseline and 8 weeks after intervention.

AIP decreased (P<0.07) in the LS group and their levels of HDL-C and LDL-C increased compared with baseline levels, whereas in the control group no significant change was seen. In this group a decrease in TG of 4.5% was seen, whereas this increase in the control group was 22%.

Consumption of LS as supplementary treatment in type 2 diabetes could have favorable effects on lipid profiles, fasting blood glucose and reduce risk of coronary vascular diseases.

Cancer is chronic disease that its prevalence is growing in recent years. Genetics and environmental factors such as energy balance and nutritional habits are involved in its incidence. The nutrition plays an important role in prevention and incidence of cancer due to protective and harmful factors, respectively. The aim of this study was to assess the knowledge of medical sciences students regarding the role of nutrition in prevention or incidence of cancer in Tabriz University. This Cross- sectional study conducted on 565 (219 male and 346 Female) senior students of medical sciences. A self-administered questionnaire with two part completed by students. the one was about the demographic characteristics (age, gender, course, level of education, passing nutrition unit through the school and source of nutritional information) and the other one with 22 closed and open questions was about nutritional knowledge. Data analyzed by using descriptive statistics and presented as frequency and percent. Assessment of relationship between nutritional knowledge and demographic variable were used the Pearson correlation and ANOVA. About 13% of students had low level of nutritional knowledge and 41% and 45.6% had acceptable and high level of knowledge, respectively. Relationship between course, level of education, passing nutrition unit through the school and source of nutritional information of students with nutritional knowledge were statistically significant and with age and gender were no statistically significant relationship. Nutritional factors had important role in incidence of cancer and individual knowledge in this regard is important. In our study, medical knowledge of students, as future provider of health information hadn´t adequate level, so using of efficient coeducational materials for increasing their knowledge may be beneficial.

Reliable findings indicate that inflammatory factors and glycosilated hemoglubin (HbA1c) disorders has the main role in pathogeneses of diabetes and its complications. Traditionally plant extracts have been used for diabetes control. This study was aimed to examine the effect of total and different fractions of black tea on inflammatory factors and glycosilated hemoglobin (HbA1c) in diabetic rats. This study was conducted on 56 rats which were randomly divided into 8 groups (7 rats in each group)and they were studied for one month. The weight of rats was 200 – 250 gr. Groups 1 and 2 were non-diabetic, groups 3–8 were diabetic, and diabetes was induced by intraperitoneal injection of streptozotocin 60mg/kg. Groups 1 to 8 were received by intraperitoneal injection: vehicle, total extrac (50mg/kgw), vehicle, total extrac (50mg/kgw)t, methanol fractions of 20%, 40%, 60%, 80% plus 100% respectively. In the end of study blood samples were taken from all groups and glycosilated hemoglobin (HbA1c) and inflammatory factors: Interleukin-1,6, TNFα and CRP were measured. In this study concluded that injection of total extract and 20% fraction of black tea had decreased inflammatory factors in diabetic and non diabetic rats (p<0.05). but did not on glycosilated hemoglobin (HbA1c). It can be concluded that injection of total extract and 20% fraction of black tea had positive effect on inflammatory factors in diabetic rats

Reliable findings indicate that lipid profile, oxidative stress and inflammatory factors disorders has the main role in pathogeneses of diabetes and its complications. Traditionally plant extracts have been used for diabetes control. This study was aimed to recognition of the most components in the most effective hydromethanolic fraction of Iranian black orthodox tea on lipid profile, oxidative stress and inflammatory factors in type I Diabetic rats. This study was conducted on 35 rats which were randomly divided into 5 groups (7 rats in each group). The weight of rats was 200 – 250 gr. Total of groups was diabetic, and diabetes was induced by intraperitoneal injection of streptozotocin 60mg/kg. Groups 1 to 5 were received: carrier, methanol fractions of 20%, 40%, 60%, 80% plus 100% respectively. In the end of study biochemical factors was measured. Data were analyzed by using one ways ANOVA, SPSS statistic methods. Analytical, Preparative and NMR were used to recognize of components in the most effective fraction. In this study concluded that the effective fraction on biochemical factors was 20%. The main component of 20% fraction were caffeine, epicatechingallat, quercetin and kaempferol. It can be concluded that injection of 20% fraction of black tea had positive effect on the prevention of incidence and develop of diabetes complications.

Diabetes is one the most common endocrine disorders, obesity, improper nutrition, and inactivity was considered as proposing factors. Historically plant extracts are used for diabetes control. This study was implemented to determine the effect of total and different fraction of Iranian black orthodox tea on weight, food intake and blood sugar in type I diabetic rats. This study was conducted on 56 rats which were randomly divided in to 8 groups (7 rats in each group). The weight of rats was 200 – 250 gr. Group 1 and 2 was non-diabetic, groups 3 – 8 were diabetic, and diabetes was induced with intraperitoneal injection of streptozotocin 60mg/kg. Group 1 to 8 received carrier, total extract, carrier, total extract, methanol fractions of 20%, 40%, 60% and 80% plus 100% respectively. Blood sugar was measured beginning and end of intervention, weight and food intake was measured each week during intervention (5 times). Data was analyzed by using one and two ways ANOVA, repeated measure and nested variance. Food intake and weight was reduced, in 40% fraction received group, significantly more than other groups (p=0.000).also total extract decreased food intake significantly (p 0.000). There were no significant differences between other groups. Change in Mean blood sugar between groups during intervention was not found statistically significant. It can be concluded that injection of total extract and 40% fraction of black tea had positive effect on decreasing of food intake in diabetic rats and prevention of obesity. Therefore consumption of black tea might prevent from diabetes and its complications.