مهدی یوسفی

The present study aims to investigate the factors influencing business continuity marketing under conditions of uncertainty in the gas industry. Criteria such as factor loadings using the value of 0.4, Cronbach's alpha, and R2 and Q2 criteria were utilized. Then, using t-statistics and path coefficients, the impact of the variables under investigation on business continuity under conditions of uncertainty was analyzed. Due to the indefinite and unlimited number of members in the population, 384 individuals were determined using the Cochran formula. The results of this research indicate that the ability to finance infrastructure, specialized personnel, and business environmental requirements have a positive and significant impact on business continuity under conditions of uncertainty in the gas industry. Among the variables studied, the ability to finance infrastructure had the highest impact with a path coefficient of 0.437.

 Due to the nature of healthcare services, decisions leading to changes in hospital processes are more sensitive. Therefore, managing change in hospitals requires special attention. This study was conducted with the aim of providing a framework for initial stakeholder engagement in hospital change management to improve efficiency.

 This applied study by qualitative method and nominal group technique with a targeted selection of 22 people, including 68% women and 32% men, with an average experience of 8 years ,with leadership experience or involvement in successful change processes in hospitals or relevant research at Mashhad University of Medical Sciences were purposefully selected. In total, eight main sessions and ten smaller sessions were conducted. The sessions were managed using the Potter nominal group technique in five stages: topic clarification, idea generation, idea sharing, discussion, and voting.

 The four main solutions included: 1)examining the acceptance of change in hospitals (including six actions: examining characteristics, history, the culture of change, achievements, related actions, decision-making centers, and examining resistance status in upper-level institutions); 2) stakeholder analysis (including identifying stakeholders, determining their power and interest levels, drawing a matrix, and identifying key stakeholders); 3) examining the level of acceptance by key stakeholders (including disbelief, belief, trust, and confidence levels); 4) engaging key stakeholders with a participatory approach (including using dialogue, deep conversation, and work partnerships).

 Effective change management at the hospital level requires sufficient attention to stakeholder engagement. In this study, the necessity of understanding key stakeholders, considering their acceptance level, and engaging them through appropriate participatory strategies within the organizational culture were emphasized for the success of the initial stakeholder engagement process.

In this study, a method for automatic prediction of the survival rate of patients with glioblastoma tumor based on machine learning methods and MRI images is presented.

The data set used in this study is the BraTS 2017 database with 163 samples. Each sample of database images has four different imaging modalities as well as information such as the patient's overall life expectancy according to the patient's day and age. Database images are labeled into three categories, short-term, medium-term, and long-term, based on patient longevity after treatment. To improve the prediction results, different types of features were extracted and taught by different machine learning methods. The considered features include texture, volumetric, statistical, and deep features. The machine learning methods used include support vector machine, nearest neighbors, linear discriminant analysis, and decision tree.

The best prediction accuracy based on the classification was obtained using deep features extracted by a pre-trained convolutional neural network (CNN) and by linear discriminant analysis.

Deep learning approaches showed a good performance in the prediction of medical parameters such as survival rate time.

Functional dyspepsia is a common gastrointestinal disorder characterized by discomfort and fullness after eating, early satiety, epigastric pain, or burning. While not life-threatening, it significantly impacts the quality of life of patients. This study reviews evidence-based interventions by Persian Medicine specialists for treating functional dyspepsia.

This systematic review was conducted in 2024, searching PubMed, Web of Science, Google Scholar, and Iranian databases such as SID and Magiran. Inclusion criteria encompassed all Iranian clinical trial articles on functional dyspepsia and complementary medicine published in Persian and English from 2000 to 2024. Keywords included terms for the disease (dyspepsia, functional dyspepsia, Helicobacter, flatulence, gastric pain, fullness, epigastric pain, fullness after a meal) and types of interventions (herbal medicine, Persian medicine, complementary medicine, Iran, Iranian medicine) in English and Persian. Abstracts of all relevant titles were screened, and articles not meeting the inclusion criteria were excluded. Full texts of the remaining articles were then reviewed for necessary information.

The findings indicate that several plants —such as Ajwain, Black Cumin, Celery, Dill, Thyme, Mastic, Pepper, Ginger, Oregano, Jollab syrup, Coriander, Amla, Rose, Basil leaves, Aniseed, Valerian, Black Seed, Savory, and Broadleaf Plantain seeds— were effective in alleviating functional dyspepsia symptoms either alone or in combination in clinical trials.

Medicinal plants recommended in Persian Medicine, whether used alone or alongside modern medicine, can effectively and safely improve dyspepsia symptoms. However, more high-quality, large-scale, and rigorously designed clinical trials are needed to establish definitive therapeutic effects.

 One of the interesting and challenging topics in healthcare systems is the methods of financing the costs of patient treatment. During the COVID-19 pandemic, the share of financial resources for patient treatment may have changed. This study was conducted to examine the changes in the share of financial resources for patients’ hospital bills during the pre-COVID-19 and COVID-19 periods.

 This descriptive-analytical study was conducted with an practical approach. The research environment was two the COVID-19 referral hospitals at Mashhad University of Medical Sciences. A total of 305,382 files were reviewed. The main source for data collection was the hospital information system. Data analysis was performed using Excel 2017 and SPSS version 25 software, using the Mann-Whitney test at a significance level of 0.05.

 The results showed that the share of basic insurance in the pre-COVID-19 period and in the covid-19 period was 70% and 72%, respectively(P=0.09). The ratio of health subsidy share decreased from 4.8 in the pre-COVID-19 period to 2.2 in the COVID-19 period (P<0.001). The ratio of patient payment share compared to the total files amount for internal-infectious patients increased by about 7% in the COVID-19 period compared to the pre-COVID-19 period (P<0.001).

 The results of the study indicate that with the spread of the COVID-19 pandemic, the share of each financial resource in the patient’s bill has changed. The increase in the share of COVID-19 patients highlights the need for structured programs to protect the financial interests of healthcare recipients during potential crises in the future.

Recurrent pregnancy loss is defined as at least two consecutive clinical pregnancy losses before 20th week of gestation. In this study, we investigated microRNA-1 and microRNA-1229 in recurrent miscarriage patients before and after lymphocyte therapy in comparison to control group.

First, a written and informed consent will be obtained from the target population of this study, who are people with RPL referring to Waliasr International Hospital. According to the standard protocol, the number of 2×107 is injected subcutaneously to patients. Real-time PCR technique will be used to check the expression level of microRNA-1 and microRNA-1229.

The gene expression level of micro-RNA 1 in RPL women before of lymphocyte therapy was 2.030±1.445 and the gene expression level of the same micro-RNA after the lymphocyte therapy of the mother was 1.101±0.4780. Also, the expression level of micro-RNA 1229 in these women was reported to be 2.100±0.6296 before treatment and 1.247±0.9631 after treatment with lymphocytes. This level of gene expression in control group, for micro-RNA 1 and micro-RNA 1229 genes is 1.000±0.08334 and 1.000±0.08091, respectively.

The results of our study showed a noticeable decrease in the gene expression of microRNAs under study, both microRNAs 1 and 1229, in women with a history of three consecutive injections of the father's subcutaneous lymphocytes.

Fault interaction creates areas of local concentration of stress and disturbances that affect the geometry and cognitive movement of faults. This stress concentration can create secondary structures in damage. In this article, the influence of the interaction or relationships between the Zagros and Arabian faults in the Zagros foreland on the formation and different geometry of the Rag Sefid and Tango anticlines is investigated and explained.

Due to the occurrence of the phenomenon of fault interaction between the faults that cause the Rag Sefid and Tengo anticlines, the three-dimensional interaction theoretical models between the fault segments are first introduced. By comparing the geometrical condition of fault parts in the study area with theoretical models, the types of fault interaction in this area are introduced. Finally, due to the dependence of the folds in the region on the fault, and with a detailed study of the geometry and dimensions of the underlying faults, the factors affecting changes in the pattern of folds are examined and the development of folds with different geometries, dimensions, extensions and mechanisms is justified.

Regarding the length more than 3 times of the Rag Sefid fault respect to the southern part of the Hendijan-Izeh strike-slip fault, the mean slope of 47 degrees of the Rag Sefid fault relative to the Hendijan-Izeh fault of 80 degrees and according to the general compression direction of N22E in the Southwest of Iran and the southern part of the Hendjan-Izeh fault trend (N20E), as well as the Rag Sefid fault trend, which is approximately perpendicular to the general compression direction, the deformation amount of the Rag Sefid fault is more than the Hendijan fault. In this condition, the stress field of the Rag Sefid thrust fault is dominated and due to the less resistance of the rising, folding with a larger amplitude occurs on the the Rag Sefid anticline; so that the folding amplitude in the Rag Sefid anticline is more than twice as large as the Tango anticline, and the tip of the Tango anticline is about 1,200 meters lower than the Rag Sefid anticline.

It can be concluded that in a set of faults where the interaction between the faults has occurred, larger, shallower faults with a plane slope of about 45 degrees, which have a diagonal or vertical orientation compared to the general orientation, they can create large and clearer folds similar to the folds with large dimensions in the Rag Sefid anticline compared to the Tango anticline.

Volition as an important component of the psychological element of crime is one of the important issues of criminal law, whose role in the realization of criminal responsibility has different dimensions and has always been the solution of debates and opinions. In this article, an attempt has been made to examine the role of volition in criminal responsibility from the perspective of Iranian and French jurisprudence and law. The current article is descriptive and analytical and has investigated the mentioned question by using the library method. The findings indicate that both in Iranian jurisprudence and French law, although material behavior is necessary for the realization of criminal responsibility, it is not sufficient and it is necessary that this behavior is done with free volition. Therefore, if the perpetrator does not have the volition to carry out that behavior, no type of criminal responsibility volition be realized. In fact, the basis of criminal responsibility is the volition of the behavior. If a person does not have the right to freely choose his own behavior, which means that he lacks freedom of volition or there is no opportunity for him to choose his behavior, then he cannot be held criminally responsible. In Iranian jurisprudence and law, lack of volition in cases such as coercion, reluctance, sleep and anesthesia is a civil liability. In French law, coercion in a way that is out of tolerance, as well as drunkenness and any mental disorder that destroys the volition, are responsible for blasphemy. Of course, in both Iranian and French laws, in cases such as drunkenness, the removal of responsibility does not mean the removal of compensation, and the perpetrator must compensate the damage caused to the victim.

By reviewing the literature on the concept of quality of life in sociology, psychology, human geography, and also in the fields of environmental design, it is revealed that some factors are especially related to spatial planning. Places that affect people's lives, and thus their overall quality of life, on a scale varying from individual residences or local neighborhoods to cities and regions, and even states or nations. In urban planning, a basic assumption is that places have objective and subjective characteristics that can be designed to improve the quality of individual life. In the meantime, the city of Karbala in Iraq is considered one of the important religious and historical cities in the Middle East region, which receives many pilgrims from different countries every year in addition to the native population. Therefore, the purpose of this article is to analyze the urban space construction in the quality of life of citizens in Karbala. In order to achieve this goal, a descriptive-analytical method was used. The findings of the research showed that urban spatial development in Karbala city can be analyzed based on two factors: objective and subjective factors. Objective factors include the solid waste collection system, imbalance in the geographical distribution of the population, imbalance in the distribution of services to the people, the mechanism of the natural ventilation system, the city's thermal system, and subjective factors including the extratextual implementation of the power of place, the reproduction of collective identity and sanctified places. and places of cultural cartography.

Kidney stones are one of the most common urological diseases. Renal colic is a medical emergency due to severe pain, and the repetition of its periods greatly impacts the patient's life quality. Providing different treatments while increasing the patient's life expectancy causes changes in their lifestyle, health status, and life quality. This study aimed to evaluate the life quality of patients with kidney stones in Mashhad in 2019 with a review of Persian medicine.

The present descriptive-analytical study was performed on 96 patients. Data were collected by SF-36 quality of life questionnaire, researcher-made demographic questionnaire, and the Salmannejad temperament determination questionnaire. Data analysis was performed using SPSS-16 software.

The mean age of patients was 45.6 years; the mean number of stones was 18.1± 84.1 and the mean size of stones was 12.32 ± 8.53 mm. The mean and standard deviation of patients' life quality was 369.26±98.32. The highest mean was related to the physical function dimension (82.68 ± 21.8) and the lowest mean was related to the pain dimension (52.23 ± 25.47). There was a statistically significant relationship between some dimensions of life quality with blood pressure and temperament (Mizaj) variables (p <0.05).

Several factors improve the life quality of patients with kidney stones. Paying special attention to the characteristics of patients with kidney stones and modifying the type of nutrition based on their temperament can prevent the recurrence and re-formation of kidney stones.

Calculating the amount of shortening, the angle between ridges, the slope of the main thrust and the percentage of thinning of the front ridge compared to the back ridge in the middle and northwestern parts of Sulabder anticline shows the folding style related to fault propagation in these parts. The calculation of these geometrical parameters in the south-eastern part of the Sulabder anticline also shows the faulted detachment folding style. The change of folding class from 1c to 2 and 3, as well as the change of fold style from detachment folds to fault propagation style, are a sign of increased shortening, deformation progress and evolution of folding from the south-eastern part. This represents that in the initial stage the thrust fault system belongs to the middle and north-western parts, which are in the developed stages of the thrust fault system. The interpretation of seismic sections perpendicular to the Sulabder anticline in different sections shows that the Sulabder anticline in a raised wedge form is higher than the adjacent structures due to the action of the thrust faults on the northern and southern edges. In the Solabdar anticline, the performance and mobile behavior of marl-shale units of Pabdeh and Gurpi formations, due to its high thickness and formable rheology as an intermediate separation horizon, create different folding styles at the top and bottom of this unit. It also caused displacement in the axis of the upper and deeper parts of anticlines.

Continuous evaluation of medical record documentation is needed for a quality patient care. This study aims to evaluate the status of nursing documentation before and after providing feedback to nurses in the emergency department (ED) of a hospital in Mashhad, Iran.

This quasi-experimental study was conducted in the ED of Imam Reza Hospital in Mashhad in 2022. First, the ED nursing documentation assessment tool was developed based on the literature review and its psychometric properties were evaluated. Then, 150 medical records were randomly selected from the ED and examined by this tool. The results of assessment along with the guideline for correct documentation were given to the nurses as feedback in a video format. One month after, 150 medical records were examined again and the results compared. Data were analyzed in SPSS software, version 22 using the independent t-test, chi-square test, and Fisher’s exact test.

Of 22 indicators in the initial draft of designed tool, 18 obtained acceptable CVR (>0.56) and CVI (>0.79). Cronbach’s α coefficient for the designed tool was obtained 0.85. The mean score of nursing documentation before giving feedback was 27.9±2.1 (out of 36) which increased significantly to 29.1±1.6 after giving feedback (P<0.001). The highest percentage of incomplete documentation was related to the triage form and compliance with the principles of correction or addition.

The status of nursing documentation in the ED of study hospital can be improved by the feedback method. It is recommended to regularly evaluate the nursing documentation status in this department and provide feedback to the nurses.

Wet cupping is one of the therapeutic or preventive bloodletting methods with a long history that is recommended during certain times in Persian Medicine sources, but there is no recommendation regarding the amount of blood flow. The aim of this study was to investigate the effect of time and circumstances of the applicants on the amount of removed blood.

This is a descriptive cross-sectional study, by easy sampling method with 739 participations of men who referred to a fixed center for wet cupping in Saveh city in 2022. The data was collected using an Information gathering form, and analyzed by SPSS-16.

Totally 739 men were referred. The average age was 34.91 years, height 174.92 cm, weight 80.32 kg and body mass index (BMI) was 26.25. The mean amount of blood excreted during cupping was 89.04 g. The amount of exited blood during cupping had a positive correlation with day and lunar month as well as age, height, weight, BMI, history of cupping, and the number of previous cupping records, and the statistical difference was significant (P <0.001) but the based on its doing time (day of the week and solar month) was not significant (P> 0.05).

The amount of excreted blood during cupping has a statistically significant relationship with age, height, weight, BMI, previous cupping history, and time of cupping.

The diagnosis and treatment of cancer is stressful and perceived stress and concerns during the treatment period can add to this stress and affect the recovery of patients with gastrointestinal cancer. The aim of this study was to investigate the relationship between illness perception and coping styles, and perceived stress in patients with gastrointestinal cancer.

The present cross-sectional correlational study was conducted in 110 patients with gastrointestinal cancer in Sari Imam Khomeini Hospital, Iran 2022, selected by convenience sampling. Data were collected using a demographic questionnaire, The Brief Illness Perception Questionnaire (Brief IPQ), Billings and Moos Coping Styles Questionnaire, and Perceived Stress Scale (PSS). Finally, the data were analyzed applying descriptive statistics and Chi-square, independent t-test, Pearson's coefficient correlation, and ANOVA.

Most of the participants were females (50.9%), with a medium income level (59.1%), living in the city (91.8%), suffering from colon cancer (40.9%), and undergoing treatment (90.0%). Findings showed that most of the patients had a high level of perceived stress (57.3%), moderate levels of illness perception (71.8%), and moderate coping styles (71.8%). We observed an inverse relationship between perceived stress and illness perception (P<0.001, r=-0.604), but there were no significant relationships between perceived stress and coping styles (P=0.064, r=-0.177) and other demographic variables.

Considering the inverse relationship between illness perception and perceived stress, healthcare managers are suggested to take measures to improve the illness perception of patients with gastrointestinal cancer.

Due to the importance of predicting and monitoring river water quality parameters, in the present study, the capability of two models of support vector machines (SVM) and gene expression planning methods (GEP) used to estimate two water quality parameters namely the TDS and SAR in the Tajan River. To estimate the TDS and SAR, parameters which the measurement of these parameters are easy and has low cost, were used as input data to the model. These parameters included the electrical conductivity of water, acidity, sodium, calcium, potassium, the adsorption ratio of sodium, magnesium, chlorine, sulfate, bicarbonate, and river flow. SPSS was used to determine the correlation between independent and dependent variables. Based on data analysis using step-by-step method, different scenarios of combining input data for TDS and SAR prediction were considered. Comparison of the results using statistical criteria showed that the use of three variables, EC, SO4 and SAR in estimating TDS in Tajan river, had the highest correlation coefficient and the lowest error rate. The Na and EC variables also give the best results in estimating the river SAR parameter. In general, the obtained results show the high performance of gene expression planning method in estimating the quality parameters of the Tajan river and therefore it can be used to predict the qualitative parameters of rivers.

Considering the important role that nurses' social responsibility has in improving the quality of nursing services, it is necessary to investigate the factors related to it. Therefore, this study was conducted with the aim of determining the relationship between nurses' social responsibility and organizational structure in teaching hospitals of Kurdistan University of Medical Sciences.

This research was a descriptive-analytical study. The statistical population included all nurses working in three teaching hospitals affiliated with the Kurdistan University of Medical Sciences, including Kowsar, Be`sat, and Tohid hospitals in Sanandaj city in 2019. Using Cochran's formula, 317 people were determined as the sample size and were selected by stratified random method. The tools used included the demographic information form, Carroll's (1991) social responsibility questionnaire, and Robbins and Evanswij's (1983) organizational structure questionnaire. SPSS-24 software and Pearson and MANOVA statistical tests were used for data analysis.

The average scores of social responsibility and organizational structure of nurses working in the studied hospitals were 131.72 and 53.45, respectively. There was a direct and significant relationship between nurses' social responsibility and its components (legal, economic, legal, economic, ethical altruistic) with the organizational structure of hospitals and its components (formality, concentration, and complexity) (p<0.05).

Providing the context to change the organizational structure of the desired state can play a significant role in increasing and improving the social responsibility of nurses in educational hospitals affiliated with the University of Medical Sciences. Which can be the foundation of quality and increase efficiency in teaching hospitals.

The last two decades have seen an increase in the number of studies examining resilience to suicide, and a large number of studies have now been published on the subject. The aim of this study was to construct a structural model of Structural pattern of psychological hardiness, religious beliefs with resilience to suicide: The mediating role of positive dimensions of self-compassion. The research method is descriptive-correlation modeling of structural equations. The statistical population of this study consists of all high school students in nourabad (Delfan) in the academic year (2020 s.c.). The research sample was 350 high school students in nourabad Delfan city who were selected by cluster sampling method and used the psychological hardiness questionnaires of Maddi et al. (1982), religious beliefs developed, resistance to Osman's suicide et al (2004) and the positive dimensions of compassion responded to Reese et al (2011) online. Structural equation modeling and AMOS edition 22 and SPSS 26 were used to evaluate the proposed model. The results of the correlation coefficient showed that there was a positive and significant relationship between the dimensions of religious beliefs, psychological hardiness with positive dimensions of self-compassion and resilience to suicide (P≥0.001). The findings indicated that the proposed model fit well with the data. The results of structural equation modeling showed that 62% of the variance of positive dimensions of self-compassion is explained by religious beliefs, psychological hardiness and 69% of the variance of resilience against suicide is explained by religious beliefs, psychological hardiness and positive dimensions of compassion. Low levels of religious beliefs, psychological hardiness, and negative dimensions of self-compassion can be considered as an aggravating factor in suicide attempts that increase the severity of the relationship between risk and suicide attempt.

Considering the challenges that COVID-19 disease has created in human life, the study of its various dimensions is one of the topics of interest today. Considering the important role of nurses in combating this disease, in this study we examined the level of knowledge and job stress of nurses working in COVID-19 and non-COVID-19 wards and their relationship with each other.

 We assessed the awareness and job stress of 215 nurses working in COVID-19 wards and also 142 nurses working in other wards in Imam-Reza and Ghaem hospitals in Mashhad, using a researcher-made questionnaire as well as the JRTI questionnaire.

 The mean score of nurses' knowledge was 68.19 ± 17.44. The level of knowledge of nurses working in COVID-19 ward was significantly higher than nurses working in other wards (p = 0.002). The mean score of job stress in nurses was 58.82± 13.17 and there was no significant difference between job stress of nurses working in COVID-19 wards and nurses working in other wards (p = 0.134). There was a negative relationship between awareness and job stress of nurses (r = -0.14, p = 0.007).

Increasing the level of nurses 'awareness reduces their job stress, which shows the importance of increasing nurses' awareness about COVID-19 disease by providing appropriate training.

Carrying out scientific activities in various biological, agricultural, pharmaceutical and industrial fields in a region requires knowing and introducing the collection of plants in that region. The study of plant biodiversity in Central Zagros is important from different aspects and has been the focus of attention. In this research, the flora of a region of Eastern Kiyar including 5 villages located in Chaharmahal and Bakhtiari province was investigated. Plant specimens were collected and identified in two vegetative periods, and traits related to the biological form, belonging to the vegetative area, condition, and medicinal potential of the species were determined. The results showed that the flora of this area consisted of 269 species belonging to 181 genera and 48 genera. The most important families in terms of the number of species were Asteraceae (51 species), Fabaceae (24 species), Brassicaceae (23 species), and the largest families in terms of the number of genera were Asteraceae (27 genera), Brassicaceae, (17 genera), Poaceae (16 genera) and Lamiaceae (13 genera) respectively. The study of the frequency of vegetative forms by the Raunkiaer method in the flora of the region showed that 47% of the species were hemi-cryptophyte, 32% of the species were therophytes, 12% geophytes, 6% chamophytes and 2% phanerophytes. Also, 188 species (70%) belonged to the Iran-Turani vegetation zone. Among the species, 66 medicinal species and two species in critical conservation status were detected.

Cupping is one of the preventive and treatment methods in traditional Iranian medicine, which has two types, dry and wet cupping. The important point is that cupping should be done at the appropriate time and place and by the qualified people to have the most beneficial effects. This study aims to investigate the reasons for wet cupping therapy in Haziran, and the people’s knowledge of the cupping principles.

This descriptive cross-sectional study was conducted in 2019 in Mashhad and Birjand cities during the last days of June. Finally, 400 eligible samples participated in this study who were selected using a convenience sampling method. The collected data were analyzed in SPSS v. 16 software.

Of 400 participants, 392 completed the questionnaires; 62.8% (n=246) were male, 75.1% (n=292) were married. 40.3% (n=154) had a university education, and 77.7% (n=289) had moderate socio-economic status. 82.2% (n=53) of the women were housewives; 6.6% (n=26) of participants had an underlying disease, 40.8% (n=119) had a history of cupping two times or more in a year, and 42.7% (n=132) had moderate satisfaction with cupping therapy. The most common reason for cupping was the “maintenance of health” (73.9%, n= 272) followed by “disease treatment”. Regarding the people’s knowledge of the principles of cupping, it was found that more than half of  participants had correct information about the best season  (spring) for cupping  (81.5%, n=255), satiety during cupping (74.4%, n=210), the best time for having bath after cupping (after 24 hours) (79.7%, n=240), what to eat after cupping (Honey syrup) (64.7%, n=189) and complications of cupping (69.3%, n=185), but their knowledge was not desirable in other areas such as the best hours of day for cupping (46.9%, n=130), the best day of the week for cupping (21.3%, n=62), and the best days of month for cupping (35.6%, n=86).

Due to the high popularity of wet cupping in Haziran in Iran, and considering the people’s low knowledge of the proper principles and conditions of cupping (such as the time of cupping), it is necessary to inform the community through the media and use specialists in traditional medicine to monitor proper cupping and observance of its principles in the cupping clinics.

Evaluation of treatment response is one of the most challenging tasks in the treatment planning of cancer cases. Regarding the significant effect of tumor recurrence in the treatment planning of patients with lung cancer, finding an approach to predict the recurrence of these tumors is of great importance. Nowadays, this process is done experimentally, and its accuracy depends on the experience and proficiency of the oncologist. This study aimed to provide an automated method to detect the recurrence of lung cancer based on imaging and clinical features.

Our proposed method was evaluated in 162 patients with non-small cell lung cancer (NSCLC) using the NSCLC radiogenomic database in the Cancer Imaging Archive (TCIA) portal. After pre-processing, segmentation was performed using the Otsu method. In the next step, the radiomic features were extracted using pre-trained AlexNet and GoogleNet models, and along with clinical features, they were used to detect lesion recurrence. Finally, all cases were classified into two classes using machine learning methods.

The proposed method used clinical and deep features. The classification was done using various models, and the accuracy of the support vector machine by AlexNet features resulted in the highest performance. The mean values of accuracy, sensitivity, and specificity for this model are 99.76, 99.77, and 99.76%, respectively.

The main finding of this study was revealing the capability of deep learning methods in extracting features from medical images. For example, the AlexNet was able to extract features from CT images of NSCLC patients, which are very helpful in the recurrence prediction of these lesions.

Medical record documentation by physicians in the emergency department is very important because it determines the required services of patients in the next step. This study aimed to design and implement appropriate tools for the rapid assessment of physicians' documentation in the emergency department.

The present study was a cross-sectional study. First, a comprehensive review of resources was done in Google Scholar, PubMed, Web of Science, Scopus, Iran doc, and SID until 2021. Physician documentation indicators were provided to health information management specialists, emergency medicine specialists, forensic specialists, and the head of the HIM department in hospitals. Intra-class correlation coefficient (ICC) was used to evaluate face and content validity for instrument reliability. Then, the proposed tool randomly selected and reviewed 230 medical records of Imam Reza (AS) Hospital in Mashhad. Data were analyzed using SPSS 21 software.

First, a tool with 26 indicators was developed. Intra-class correlation coefficient (ICC) was obtained from the test of 30 medical records 0.980, which was acceptable. Seventeen indicators had scores higher than 0.79, 0.714, and 3.55 and CVR and face validity, including signature, date and time, diagnoses and procedures, correction of errors. The assessment results of 230 medical records showed a relatively good state of documentation of emergency physicians.

The proposed tool allows the rapid assessments of the key index in the documentation of physicians in the emergency department and has high validity and reliability, so it is recommended to be used in the emergency department.

Recurrent Pregnancy Loss (RPL) is 2 or more recurrent miscarriages before the twentieth week, which occurs in 2-5% of women of gestational age. Considering the significant role of the immune system in the process of a successful pregnancy, it is expected that in addition to the common and well-known treatments used for patients with recurrent miscarriage to date, intracutaneous lymphocyte therapy will also be effective.

30 patients with RPL with immunological disorders, and 30 patients in a control group consisting of healthy women with a history of successful pregnancies were included in the study. After receiving blood samples and initial examinations, people with RPL received lymphocytic treatment. Before and after the intervention, the expression levels of miR-146a, miR-10a, miR-106b, and miR-25 were measured in both groups and the differences caused by the effects of this intervention were examined.

The expression of anti-inflammatory miR-146a and miR-10a, in women with RPL showed a significant increase after receiving lymphocyte treatment compared to before treatment. While the expression of pro-inflammatory miR-106b and miR-25 showed a significant decrease after receiving lymphocytes compared to before treatment.

The aim of intradermal lymphocyte therapy is to increase the maternal immune system's tolerance to paternal antigens in the fetus and to modulate inflammatory responses in pregnant women with RPL. According to the results of this study, this method can be used to reduce inflammation in women with recurrent miscarriage.

Chronic neck pain is a common problem and is often associated with changes in sensory-motor functions such as decreased neck proprioception, altered neck muscle coordination, and increased postural fluctuations. The aim of this study was the effectiveness of exercise therapy in improving chronic non-specific neck pain in athletes in Khorramabad.

The present study was a pre-test-post-test clinical trial with an intervention group and a control group. Thirty athletes with chronic neck pain were purposefully selected and randomly divided into two groups of exercise therapy (n = 14) and control (n = 15). Evaluation of neck pain and disability was performed before and immediately after eight weeks of 3 sessions (15 minutes) of rehabilitation exercises by Visual Analog Scale (VAS) and Neck Disability Index from both intervention and control groups, respectively. Data were analyzed using covariance tests at the level of α = 0.05.

The results showed that the pain intensity (P≤0.001) and functional disability (P≤0.001) after eight sessions of training in athletes with chronic nonspecific neck pain were significantly reduced.

Rehabilitation exercises intervention including stabilizing and strengthening the neck improves pain in athletes with chronic neck pain and disability, so it is recommended that rehabilitation exercises be used as a suitable and practical method in treating athletes with chronic non-specific neck pain.

Nursing care activities in the times of infectious epidemics can cause double stress for nurses. The aim of this study was to evaluate the level of job stress of nurses caring for COVID-19 patients based on evidence from a large hospital.

This was a cross-sectional study in Mashhad city, Iran. The sample consisted of 323 nurses caring for 19 patients in Imam Reza (AS) Hospital in 2020 who were selected through random quota sampling. Data collection tools were demographic information checklist and NSS Nursing Stress Questionnaire.

The overall level of stress was moderate (62.44 out of 102). Overall stress in specialized wards and in nurses with a history of activity in infectious wards were 8% and 1% less than others, respectively. Nurses' job stress in terms of interpersonal relationships and the performance of supervisors in normal wards was higher than special wards (P value=0.020).

Based on the findings of this study, it is possible to reduce the level of stress by training nurses and simulating the ICU environment to prepare for emergencies and epidemics, as well as encouraging them to rotate work between the ICU and inpatient wards during service.