amir

Tomato (Solanum lycopersicum) is one of the most important economic and widely used crops in horticulture. It is a self-fertilizing and diploid plant and has 24 pairs of chromosomes (2n=2x=24). The life cycle of this plant is one year, and it is cultivated in greenhouses and fields. There are many varieties of tomatoes that differ from each other in terms of plant growth, quality, fruit shape, and other traits. Tomato fruit has a high nutritional value, consisting of minerals, vitamins, fibers, citric acid, β-Carotene and ascorbic acid. Diversity and selection are the two main pillars of any reformation program, and choosing is based on the existence of desirable diversity in the reformation materials under discussion. To produce varieties of tomatoes with high productivity, quality and resistance, breeders need evaluation of genetic diversity, identification and introduction of new genotypes. In other words, systematic study and evaluation of germplasm is of great importance for current and future agronomic and genetic improvement of the crop. Different methods are used to estimate genetic diversity and group genotypes, and the evaluation of morphological and physiological characteristics can be considered as the first step in the investigation of genetic diversity. Different genotypes of tomato differ in terms of morphological and physiological traits, and fruit yield is influenced by some of these traits. Therefore, the selection of criteria other than fruit yield, which have more stability than fruit yield, can be considered as a selection guide in the selection of desirable cultivars. Accordingly, this study was conducted with the aim of investigating the genetic diversity and grouping of tomato genotypes (53 genotypes) based on morphological and physiological traits.

In the present study, 53 genotypes of tomato plants were investigated using a randomized complete block design with three replications under greenhouse conditions at the Gorgan University of Agricultural Sciences and Natural Resources. After disinfecting and planting the seeds in the pot, sampling of the seedlings was performed. Morphological traits such as plant height, stem diameter, fresh and dry weight of the plant, number of side branches, number of leaves, root length, fresh and dry weight of the organ air, fresh and dry weight of roots, fruit number, fruit yield, and physiological traits including proline content, photosynthetic pigments (including chlorophyll a, chlorophyll b, total chlorophyll, and carotenoid), and total phenolic and flavonoid compounds were measured. Furthermore, the obtained data were subjected to variance analysis, mean comparison, correlation coefficient, factor analysis, and cluster analysis using suitable software.

After analyzing the data, the results of the evaluation of variance showed that the difference of the studied genotypes in terms of all traits except proline trait was significant at the probability level of 1%. Estimation of the correlation coefficients between the studied traits showed a significant correlation between most of the studied traits and fruit yield. Further, the results of the investigation into factors showed that 6 factors explained more than 77% of the total variance, so that the contribution of the first to sixth factors was 24, 18, 14, 9, 7, and 6% of the total changes, respectively. For better interpretation, larger factor coefficients for each factor were considered significant. Because the largest factor coefficients among the coefficients of each factor indicate the attribute or attribute that plays the greatest role in those factors, the factors were named accordingly. In this way, the first factor was named the fruit yield factor, the second the photosynthesis factor, the third the phenolic factor, the fourth the root weight factor, the fifth the proline factor, and the sixth the stem diameter factor. Based on the results of the cluster analysis, it was observed that the genotypes were significantly different in terms of the measured morphological and physiological traits and they were placed in 3 different groups, each of which had 30, 19, and 4 genotypes, respectively, and the genotypes in the group Third, in terms of studied traits, they were better to other groups.

In general, based on the analysis, the genotypes were significantly different in terms of the measured traits. This article shows that there is a suitable diversity among the studied genotypes and it is possible to select based on these characteristics among the studied genotypes and the selection can be effective in their improvement programs. By estimating the phenotypic correlation coefficients, it was found that the fruit yield trait had the most positive and significant correlation with the number of fruits and the amount of photosynthetic pigments. Therefore, these traits can be considered in tomato fruit yield genetic improvement programs. Considering that the average of most of the traits studied for the genotypes belonging to the third cluster (13, 15, 45 and 46) was higher than the total average and the said genotypes were excellent in terms of developmental and physiological parameters compared with other genotypes, the top genotypes identified in this research can be considered and used in future breeding studies in this valuable plant.

Each person's behavior is the basis for making his decisions in the financial arena, and mistakes in those behaviors will have many consequences. Recognizing the behaviors and consequently the decisions and behaviors of the individual has an important role in providing solutions to correct existing deviations. in order to explain the model, the interview method and the approach based on grounded theorizing, and to select the interviewees, the snowball sampling method has been used. After conducting 19 interviews with stock market activists during 1397 to 1398, theoretical saturation was obtained. Then, the most effective causal factors were determined and ranked based on the opinions of experts and using Demetel technique and Analytic Hierarchy Process (AHP), respectively.The extracted results were analyzed using Spss and Amos and showed that all biases have a direct and significant impact on investor decisions.

Rivers are the main factor that changes the shape of the earth. River geomorphology studies the forms and processes of rivers and their change and evolution and the role of humans and the interactions between them. Urban rivers are one of the ecosystems that have been destroyed and manipulated due to ill-considered and unscientific human interventions. The Kan River Corridor, as one of the most important rivers in Tehran, has not been an exception to these changes. Due to human changes in the bed of this river and its canalization, the natural and ecological functions of this river have been reduced and disturbed. The Kan River in Tehran is facing it. The purpose of this study is to investigate and analyze the conditions and morphological quality of the Kan River in Tehran using the MQI model. In this regard, using field observations and Google Earth images, 6 intervals were determined and identified along the way. After reviewing and scoring 28 indicators using MQI model, interval 2, ie Bustan Javanmardan, showed very poor morphological quality and intervals 1, 3 and 4 showed poor quality. Only two intervals 5 and 6 in the lower part of the corridor, ie airport areas. And sand mines were of moderate quality. In general, the morphological quality of the whole river corridor was evaluated as poor with a score of 0.4.

The use of hydrogenated oils in the preparation of pastries is associated with increased levels of trans fatty acids (TFAs) in these products. The purpose of this study was to determine the types and amounts of fatty acids with emphasis on TFAs, as well as comparing them with the national standard. Furthermore, the effect of labeling on the reduction of TFAs was investigated in traditional pastries. 

A total of 369 samples from Iranian traditional pastries in different brands were purchased from supermarkets located in Isfahan and their saturated fatty acid content was measured using gas chromatography. Statistical analysis was performed using SPSS version 23.

The total average of TFAs in the samples was 1.6% (0.04-7.9) in total fat. Date cookie, Yazdi cake, and Walnut cookie were healthier than other sweets due to their lower levels of TFAs and higher levels of unsaturated fatty acids. 78.1% of the samples had less than 2% TFAs in total fat. In some products (Baghlava, rice cookie), labeling was significantly associated with decreased TFAs of the product (P<0.001). In general, packed samples had a lower average of TFAs than unpacked types, however, this difference was not statistically significant (P = 0.13).

A total of 41.18% of the products had less than 1% of TFAs in total fat which complied with the national standards of Iran. In some products such as raisin cakes and muffins, TFAs exceeded 1% of the total fat content, which is a risk for people with high blood lipids.

More than a year has passed since a series of protests began in France called the “Yellow Vests Movement”. During this period, the dominant image of the official French media of protesters is as follows: They break the windows of stores, shops and banks and create violence and chaos wherever they are. It can be said at the outset that this movement has a fluid, vague identity and that analysts are seeking to understand the logic of the protests more closely. The present text is a translation of Lupine’s journal interview with Vincent Tibrej, a professor of political science at Emile Durkheim Center in Bordeaux, a political sociologist who has been exploring new citizen mobilization dynamics and the transformation of fan relationships in the context of the current generation since 2014. In this interview, he cites the effects of generational changes on the emergence of new types of protests in France, including the specific effects of the emergence and social emergence of the “baby boomers” generation, the effect of lowering social trust in electoral politics, and of Other types of non-electoral politics in the shadow of social legitimization speak of voting mechanisms, the effect of the communications revolution on protests, the points of commonality and differences in the way protests are analyzed in relation to Gustave Le Bon’s model of analysis in “Crowd Psychology”.

Most audiologists who entered the field do not receive specific training in counseling and were given little guidance on how to communicate effectively every clients. Although it is an integral part of clinical practice, counseling in audiology is only now beginning to evolve into a well-defined and systematic process. Audiologists as nonprofessional counselors can help patients who are angry, hostile, depressed, or anxious about how their hearing loss is affecting their lives. Very different approaches to counseling do exist, approximately 400 and this number has continued to rise. This approaches fall into four main categories:1) cognitive/rational, 2) behavioral, 3) affective/humanistic, and 4) eclectic. As there is no one theory or therapy approach fits all situations, and a clinician may actually apply multiple therapy approaches with any one client, patient, or family. The theoretical and therapy approaches that an individual clinician selects and uses often depends on the clinician’s personal orientation (e.g., humanistic, behavioral), what the clinician has learned in her training, and what has worked for the clinician in the past. There is no one “right” theoretical or therapeutic framework, although empirical research during the last couple of decades has provided more validation for some therapeutic approaches than for others. As audiologists working with a wide variety of hearing, speech, language, cognitive disorders of individuals of all ages, they need to be able to draw upon concepts, strategies, and techniques from a variety of counseling frameworks to communicate effectively with their clients, patients, and their families. This Article review of each of these approaches is provided to expose the audiologist to the options available when counseling deaf/hard of hearing parents.

Isthmoceles are described as complications associated with caesarean section (CS). Only symptomatic isthmoceles should be treated. The main symptoms are abnormal uterine bleeding (AUB) in the absence of any other causes, pelvic pain and secondary infertility. There are several techniques described for the correction of isthmoceles. Isthmoplasty can be performed by hysteroscopy, laparoscopy or vaginal surgery. The aim of this study was to assess the effectiveness of hysteroscopic surgical treatment of isthmoceles in women with associated symptoms such as pelvic pain and AUB. A prospective case series study was performed; this study included all women with AUB, pelvic pain and ultrasonographic (US) diagnosis of isthmocele, who had undergone hysteroscopic correction between June 2014 and December 2017 in our Hospital. Thirty eight women underwent surgical hysteroscopy for correction of symptomatic isthmoceles. All patients presented AUB, 42.1% experienced pelvic pain and 28.9% had secondary infertility. US evaluation of isthmoceles was performed using 2D ultrasound. The residual myometrial thickness (RMT) above the isthmocele was measured in women who expected future pregnancy; if it was <2.5 mm the patient was not included in the study because the correction was performed laparoscopically. Follow-up was performed one and two months after the surgery. In all cases, pelvic pain was resolved one month after the surgery. AUB disappeared within the first month in 87.5% of patients and in the second month in 96.8% of subjects; however, one patient needed further surgery to alleviate her symptoms. Secondary infertility was assessed one year after surgical isthmoplasty. Seven women completed the first year of follow up, and three of them (42.8%) reported pregnancy after treatment between six and eight months after the surgery. Hysteroscopic correction of symptomatic isthmoceles may constitute a safe and effective technique for patients who present AUB and pelvic pain.

Increased activism of the Islamic Republic of Iran in the Middle East since 2005, in the form of a coalition called the Axis of Resistance accompanied by the display of power in Iraq, Syria, Lebanon and Yemen, has raised Iran as a regional power. This show of power is due to the unique position and characteristics of the interior, along with the impact of regional and international events. This paper uses the analytical-descriptive method based on library and internet resources to answer the question of what role the components of national power have been in increasing the regional power of the Islamic Republic of Iran? The findings of this research show that four variables of geographic location (geopolitics-geo-economics), economic components (economic growth rate, oil revenues, GDP, GDP per capita, exports and imports), military power component (strategy, costs, military equipment and role The IRGC in regional politics) and the adoption of Shi'a Islam identity has had an important influence on increasing the regional influence and power of Iran.

In this paper, the operation of a future distribution network is discussed under the assumption of a multi-carrier microgrid (MCMG) concept. The new model considers a modern energy management technique in electricity and natural gas networks based on a novel demand side management (DSM) which the energy tariff for responsive loads are correlated to the energy input of the network and changes instantly. The economic operation of MCMG is formulated as an optimization problem. In conventional studies, energy consumption is optimized from the perspective of each infrastructure user without considering the interactions. Here, the interaction of energy system infrastructures is considered in the presence of energy storage systems (ESSs), small-scale energy resources (SSERs) and responsive loads. Simulations are performed using MCMG which consists of micro combined heat and power (CHP), photovoltaic (PV) arrays, energy storage systems (ESSs), and electrical and heat loads in grid-connected mode. Results show that the simultaneous operation of various energy carriers leads to a better MCMG performance. Moreover, it has been indicated that energy sales by multi sources to main grids can undoubtedly reduce the total operation cost of future networks.

The emergence of geopolitical changes in Iran's security environment, along with the consolidation of the Shah in the late 1960s, led to an increase in the regional role of the Pahlavi regime. It was on this basis that the Pahlavi regime, exerting itself as a regional power, expanded its influence in the Persian Gulf, trying to maintain regional stability and security, sometimes through coercion and sometimes through diplomacy and the expansion of relations with neighbors. Acted as a gendarmerie. The purpose of this article is to answer the question of what factors and how has the role of the Pahlavi regime as a regional power been influenced? Initial findings show that at the international level, the structural pressure of the international system is reduced by factors such as Cold War tensions, Britain's withdrawal from the Persian Gulf, and Nixon's doctrine coupled with the development of domestic capabilities leading to a triple role of leadership, Custodianship And regional protection for the Pahlavi Regime. In fact, given the Persian Gulf's blockade of the West and the Shah's relations with Washington, the Pahlavi regime succeeded in securing the region from the United States.

Nowadays, partial nephrectomy (PN) has specific indications in renal tumors. There are challenges regarding the remaining and seeding of malignant cells after surgery due to increasing tendency to do laparoscopic PN (LPN) and consequently increased manipulation of the surrounding tumor tissue. The objective of this study was to investigate the frequency of renal capsule invasion (RCI) and perinephric fat infiltration (PFI) in patients with renal cell carcinoma (RCC) who had underwent PN.

Clinical data and pathologic samples of 101 patients who underwent PN and had RCC from 2011 to 2012 were elicited. Sixty one patients underwent LPN and 40 patients underwent open PN (OPN). All pathologic samples were reviewed by an uropathologist. Fuhrman nuclear grade, surgical margin and prevalence of RCI and PFI were also determined.

The mean tumor size was 40.7 mm (range: 15mm to 120mm). In all cases, the renal capsule and perinephric fat were left intact. Surgical margin was involved in four cases of LPN. Three patients had recurrence during follow up time (follow up durations were 12, 16, and 24 months for each). The fourth one was expired during 30 months follow up despite performing radical nephrectomy.

Based on the results obtained in this study, the probability of RCI and PFI is low and hence manipulating and removing the perinephric fat to achieve better exposure to tumor will not increase the risk of seeding malignant cells.

Milk intolerance is a common problem in a preterm neonate with low birth weight, which results in the need to feed through the vessel with its many complications. Erythromycin is an antibiotic with prokinetic properties that can have beneficial effects in the treatment of this disorder. This study was performed to evaluate the effect of moderate dose erythromycin on the treatment of intolerance to nutrition in preterm infants. In this randomized clinical trial, the neonates were randomly divided into two groups receiving erythromycin (20 mg/kg/day) or placebo, and the number of cases of milk intolerance (milk lavage), milk filling time, necrotizing enterocolitis, duration of hospitalization, probable complications of erythromycin, such as hypertrophic pyloric stenosis, and other cases were compared in both groups. 64 preterm infants with the mean gestational age of 30.1 ± 2.49 weeks were studied. The number of milk intolerance and the mean milk filling time (150 cc/kg/day) were significantly lower in the erythromycin group than in the control group (P<0.05). Other variables were not significantly different between the two groups of erythromycin and placebo (P>0.05). Erythromycin with a moderate dose was effective in reducing the incidence of milk intolerance and improving the mean time to reach the full volume of milk in premature neonates with low birth weight, and it appeared to be a safe drug for these neonates.

The design of Antibody Drug Conjugates (ADCs) as efficient targeting agents for tumor cell is still in its infancy for clinical applications. This approach incorporates the antibody specificity and cell killing activity of chemically conjugated cytotoxic agents. Antibody in ADC structure acts as a targeting agent and a nanoscale carrier to deliver a therapeutic dose of cytotoxic cargo into desired tumor cells. Early ADCs encountered major obstacles including, low blood residency time, low penetration capacity to tumor microenvironment, low payload potency, immunogenicity, unusual off-target toxicity, drug resistance, and the lack of stable linkage in blood circulation. Although extensive studies have been conducted to overcome these issues, the ADCs based therapies are still far from having high-efficient clinical outcomes. This review outlines the key characteristics of ADCs including tumor marker, antibody, cytotoxic payload, and linkage strategy with a focus on technical improvement and some future trends in the pipeline.

Laboratory and field experiments have shown that dispersivity is one of the key parameters in contaminant transport in porous media and varies with elapsed time. This time-dependence can be shown using a time-variable dispersivity function. The advantage of this function as opposed to constant dispersivity is that it has at least two coefficients that increase the accuracy of the dispersivity prediction. In this study, longitudinal dispersivity values were obtained for the conservative NaCl solute transport in a laboratory porous medium saturated with tap water. The results showed that the longitudinal dispersivity initially increased with time (pre-asymptotic stage) and eventually reached a constant value (asymptotic stage). Four functions were used to investigate the time variations of dispersivity: linear, power, exponential and logarithmic. In general, because of the linear increase of dispersivity during a long time of transport, the linear function with R2=0.97 showed better time variations than the other three functions; the logarithmic function, having an asymptotic nature, predicted the asymptotic stage successfully (R2=0.95). The ratio of the longitudinal dispersivity to the medium length was not constant during the transport process and varied from 0.01 to 0.05 cm with elapsed time.

Respiratory distress syndrome (RDS) is a major acute postnatal pulmonary disease that influences mostly preterm neonates. Recently, the polymorphism of immunomodulatory genes has been suggested to be associated with RDS development. We aimed at investigating the association of CNR2 gene Q63R polymorphism with the development of RDS. In this multicenter case series study, we enrolled 300 preterm newborns. The RDS was diagnosed based on the clinical and radiographic findings. The polymerase chain reaction with sequence-specific primer method was used for genotyping. 140 neonates out of 300 were diagnosed with RDS. The overall frequency of the QQ, QR, and RR genotypes of rs35761398 was 23.7%, 50.7%, and 25.6%, respectively. In the present study, the differences in birth weight, birth height, gestational age (GA), and the severity of respiratory distress were statistically significant between the two groups. We found no statistically significant differences in either allele (P = 0.624) or genotype (P = 0.461) distributions between the RDS patients and the healthy group. Gestational age of < 28 weeks has the highest impact on predisposition to RDS. No association was found between rs35761398 and RDS in a group of Iranian preterm infants.

Although posttraumatic endophthalmitis is an uncommon condition, it causes severe complications, so medical and pharmacological interventions for prevention of endophthalmitis after trauma are a major concern. Te aim of this study was to evaluate the efcacy and clinical outcome of oral cipro?oxacin versus intravenous cefazolin/gentamicin for the prevention of endophthalmitis after penetrating ocular trauma. Tis was a retrospective, descriptive single?center study, including all cases of penetrating ocular trauma seen in the Feiz Hospital, a Tertiary Referral Eye Hospital in Isfahan, Iran, between 2011 and 2017. Data systemically recorded for each patient included clinical, ophthalmological, and demographic fndings by a trained medical record abstractor or ophthalmologist reviewing patient records. Six hundred and forty?fve patients in cefazolin/gentamicin and 273 patients in oral cipro?oxacin groups were included in the study. Our study showed that the incidence of endophthalmitis was not signifcantly di?erent between the two groups (P = 0.463). In patients with either sharp or blunt penetrating ocular trauma. Oral cipro?oxacin as a prophylactic treatment could prevent posttraumatic endophthalmitis as e?ective as injectable cefazolin/gentamicin. Due to easier consumption of oral cipro?oxacin and lower systemic complications, in all patients with penetrating eye trauma, oral administration of cipro?oxacin is preferable to intravenous or intramuscular types of antibiotics to reduce the risk of posttraumatic endophthalmitis

Language acquisition is a natural developmental process and is unique to Homo sapiens in which a child acquiring his or her mother tongue as a first language.  The simplest theory of language development is that children learn language by imitating adult language. A second possibility is that children acquire language through conditioning. Noam Chomsky put forward innateness hypothesis. Piaget argued that language is a cognitive process and that linguistic development depends on general cognitive development. Lev Vygotsky proposed that although children have innate cognitive bases for language acquisition, the actual learning begins with functions that children want to express. Finally, the connectionist theory of language development suggested that children acquire language without ever figuring out the rules or even that there are rules. Although a great deal of research has been conducted, it still is not known exactly how children are able to succeed in the remarkable feat of language acquisition. Some attempts to relate cognitive and linguistic development using the Piagetian stages have not been successful. Major advances have occurred in understanding both linguistic and cognitive development, but these advances have not been shown to have a close relationship. It is not possible with the present state of knowledge to choose definitively from the different theories. It seems logical that a combination of imitative skills, an innate language acquisition device, cognitive development, and social communication interactions contribute to language development.

For many years, the conventional approach to orthognathic surgery which was orthodontic treatment prior to orthognathic surgery has been the accepted method of treatment for skeletal class III malocclusion patients. This review compared the dentoskeletal stability of treatment results between conventional orthognathic surgery methods with presurgical orthodontic treatment and surgery-first approach in skeletal class III patients. The study protocol was based on Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement for systematic review and meta-analysis. Electronic and manual searches for literature since 2011 were conducted. PubMed and Medline databases were accessed. Data extraction and analysis were performed by two independent individuals. Seven studies out of hundred-fourteen articles met the inclusion criteria and were selected for qualitative analysis. The included studies were 494 patients with skeletal class-III malocclusion. Stability of treatment was compared between surgery-first approach and conventionally treated patients. The statistical analysis confirmed that surgery-first approach did not show more stability compared with presurgical orthodontics. The surgery-first approach shortened the overall treatment duration. However, more skeletal stability in conventional treatment was assessed. Both surgery-first approach and conventional treatment with presurgical orthodontics resulted in favorable skeletal changes in class-III malocclusion patients. Moreover, these findings should be discussed further due to the variety of study designs, outcomes and biases. Current evidence in this field still needs to be expanded. The authors wish to see more well-designed randomized controlled trials with long-term follow ups to confirm the results.

Mentally retarded individuals have poor physical fitness and inappropriate body composition. The purpose of this study was toinvestigate of effect of combined exercise training program on body composition and physical fitness in mentally retarded girls.Material and twenty twosubjects from a private rehabilitation center (age: 22-30 years, intelligence quotients= 50-70) were selected and randomly divided into two groups of experimental and control. The training protocol included strength and aerobic training, eight weeks, three sessions per week, and each session 90 minutes. Part of resistance training included training with elastic bands and weight bearing resistance exercise (with respect of overload) and aerobic training included walking, jogging and rhythmic activities. Before and after training protocol body composition, general strength and aerobic power were measured. Data were analyzed using dependent and independent sample t-tests on gain scores, employing the SPSS statistical package program. The test significance level was taken as p<0.05. There were no statistically significant differences in weight (t=0.48, p=0.63), BMI (t=1.35, p=0.19), lean body mass (t= -0.23, p=0.81), fat body mass (t=0.91, p=0.37), and VO2max in Mc Ardle step test (t=1.7, p=0.1) and shuttle run test (t=-1.14, p=0.26) between groups, whereas muscular strength significantly increased (t=-4.56, p=0.001) in training group. Combined resistance and aerobic training can improve muscular strength in mentally retarded girls, whereas probably have no significantly effect on body composition and aerobic power. It suggested that exercise training program consider as a part of daily activities and curriculum in rehabilitation centers, and these training designed with longer duration and more intensity and consideration dietary regimen.

Competitive location deals with the problem of locating facilities to provide the service to the customers where other competing facilities offering the same services. Many competitive location models are presented in the literature. However, the literature on competitive location considering reverse logistic in closed-loop supply chain is rather scarce. Also, there are two main approaches in the related literature; increasing profit, and increasing market share of the service centers. Most of the studies in the literature consider one of these issues as the objective function. But, in this study it is shown that these objectives may have conflict with each other. Therefore, addressing these issues simultaneously is important for a successful design of supply chain. This study addresses a novel bi-objective competitive facility location problem in a closed-loop supply chain in a manner that increasing profit and market share are considered simultaneously. On the other hand, in the real world, the customer may choose facilities that are not necessarily close to them, because of the greater attractiveness of other facilities. Hence, in this study, a new relationship is introduced to determine the attractiveness of each potential center for customers based on the distance and quality of service centers. To solve the proposed model and tackle the computational complexity of the proposed model, two approaches are developed: LP-metric and NSGAII. Furthermore, multiple numerical instances are defined and solved with exact approach of LP-metric through GAMS and the results are evaluated in order to validate the accuracy of the proposed model. The best value of “P” in LP-metric approach is also obtained via analyzing the results. Furthermore, the performance of the NSGAII is analyzed by comparing with exact solution of LP-metric through GAMS. The results indicate that the proposed NSGAII is more appropriate than LP-metric and consequently solving the large size problems through GAMS in a logical time is impossible.

In this study, fatty acid (FA) composition of aerial parts of selected Salvia species from Iran was analyzed by Gas chromatography. The amount of FAs was quantified for leaf and shoot of species as mg per kg (mg/kg) of dry weight. The results showed that FA contents of aerial parts for studied plants varied significantly and changed between 73.05 and 739.50 mg/kg of dried weight. Caprylic (C8:0, 1.00-380.49 mg/kg), elaididc (C18:1n9t, 0.73-97.29 mg/kg), stearic (C18:0, 1.1-62.97 mg/kg), palmitic (C16:0, 1.19-36.48 mg/kg), and α-linoleic (C18:3n3, 1.34-19.36 mg/kg) acid were major identified FAs. The numerical analyze was applied on FA composition of shoot and leaf of specimens and the shoot FA composition was selected to identify the systematic position of studied species. The UPGMA (Unweighted Pair Group Method with Arithmetic Mean) dendrogram showed that the species were grouped in two clusters. Caprylic acid (C8:0), behenic acid (C22:0), and lignoceric acid (C24:0) were chief characters in the infrageneric grouping the species in the genus. S. chloroleuca and S. atropatanawere placed in cluster I and separated from other species based on shoot FA composition. The discrimination of Salvia species based on their botanical classification was supported by results. The results confirmed that FA composition of shoot are distinguishable and can be used as chemotaxonomic markers.

Artist’s paints were not exploited as ready materials from the natural sources and they were products of complex and time-consuming process of work. Training paint making techniques was a part of training program of apprentices and many Persian treatises on techniques of paint making remains from the end of 11th century onward. These references besides interviews with contemporary traditional artists and the published results of analytical studies on Persian historic artworks made a set of references for us to know about palette of Persian painters in different periods and to know about the losing the historic techniques of pigment production after importing the readymade western art materials. Current article is trying to draw a general scope of our knowledge about historic paint making in Iran basing on these above-mentioned triple references.

Food and food security is one of the most essential challenges for the increasing population of the world. Informing about the dangers of the application of antibiotics in poultry farming can encourage consumers towards healthier products and the production of organic chicken. The factors underpinning the adoption and consumption of organic chicken were explored by contingency valuation method and Tobit model. Data were collected with a self-designed questionnaire administered among 283 citizens in Urmia, Iran sampled by Mischel and Carson’s technique in spring of 2015. The results showed that people who were more aware of the benefits of organic chicken and had better attitude towards general purchase component, healthy purchase component and the awareness of the dangers of hormones and antibiotics exhibited more willingness to consume these products. The frequency of chicken consumption per week had a positive, significant impact on willingness to pay for organic chicken. The expected value of more willingness to pay per kg organic chicken was estimated at 33.92% as compared to industrial chicken as the output of Tobit model revealed. Consequently, the more the consumers are educated about nutrition and health of agricultural products, the higher their willingness would be to pay for organic products.

Phenylketonuria (PKU) is the most prevalent inborn error of amino acid metabolism in the world and its incidence rate is increasing in Iran. The aim of the present study was to assess the efficiency of HRM technique as a fast and suitable method in identifying common mutations of phenylalanine hydroxylase gene including IVS10-11G>A and P281L in order to improve the early detection of the disease to prevent the occurrence of it.
In this case-control study, 20 DNA samples including one sample with IVS10-11G>A mutation , one sample with P281L mutation and 18 control samples were extracted from peripheral blood collected in Medical Genetic Center of Isfahan and were genotyped with HRM technique. To validate the mutations, the mutant samples were genotyped using sequencing. Bioinformatic analyses were used for determining structural and functional effects of P281L mutation on the of PAH protein.
FINDINGS: HRM analysis identified IVS10-11G>A and P281L mutations with a sensitivity and specificity of 100% and the mutant and normal samples differentiated well in normalized and difference plots. Bioinformatic analyses demonstrated instability and pathological effects of PAH protein containing P281L mutation.
HRM is a simple and fast technique detecting the two IVS10-11G>A and P281L mutations with 100% sensitivity and specificity.