mojtaba moradi

Candidiasis is a prevalent fungal infection caused by various species of Candida, especially, C. albicans. The emergence of resistance to azole medications, which are frequently prescribed for the treatment of Candida infections, presents a significant challenge in the management of these infections.

The present mini-review summarizes findings from a comprehensive search of articles published between 1999 and 2024, retrieved from Scopus, PubMed, and Web of Science. Studies were selected using specific keywords based on relevance to UPC2 gene functions, azole resistance mechanisms, and C. albicans biology.

The UPC2 gene has become crucial in regulating drug resistance in C. albicans. This gene encodes a zinc (II)-Cys (6) transcription factor involved in the biosynthesis of sterols and contributes to resistance against azole antifungal drugs. When exposed to azoles, UPC2 in C. albicans enhances the expression of ergosterol biosynthesis genes, such as ERG2 and ERG11. Increased expression of ERG11 leads to reduced susceptibility to azoles by boosting the production of 14α-lanosterol demethylase, the primary target of these antifungal agents. Furthermore, UPC2 regulates sterol uptake under anaerobic conditions and manages other adaptations to environmental changes, all of which contribute to azole resistance.

Gaining insight into how the UPC2 gene contributes to azole resistance is essential for the development of effective strategies in the antifungal drug development process.

Neuropathy is one of the common complications of diabetes mellitus. This study aimed to determine the analgesic and antiapoptotic effects of the aqueous extract of Achillea millefolium L. (Ach) in rats with experimental painful diabetic neuropathy by behavioral and molecular procedures.

Experimental approach: 

Thirty male Wistar rats were divided into 5 groups including control, diabetes + saline, and diabetes + Ach extract (doses of 150, 300, and 600 mg/kg/day for 3 weeks, orally). A tail-flick test was performed to assess the pain threshold in different groups. Western blotting test was used to evaluate the apoptotic (Bax, Bcl2, cleaved caspase-3, and cytochrome-c) and inflammatory (TNF-α and NF-κB) protein factors in the lumbar portion of the spinal cord tissue. Also, commercial assay kits were used to evaluate oxidative stress factors (MDA, GPx, and SOD enzyme activity) in the lumbar portion of the spinal cord tissue.

Results showed that administering Ach extract at the doses of 300 and 600 mg/kg/day significantly increased the nociception threshold in treated diabetic animals compared to untreated diabetic animals. Moreover, the treatment of diabetic animals with Ach extract (300 and 600 mg/kg/day) significantly reduced the oxidative stress, inflammation, and apoptosis biochemical indicators in the lumbar spinal cord tissue compared to the untreated diabetic group.

Conclusion and implications:

 The findings showed that Ach extract has neuroprotective and anti-nociceptive effects in rats with diabetic neuropathy. The effects can be due to the inhibition of oxidative stress, inflammation, and apoptosis in the spinal cord tissue.

In determining the water that can be allocated for different uses, including agriculture (as the main consumer), the most important step in this era is the proper management of groundwater resources. The observance of water consumption within the limit of allocated water ensures that the consequences of the exploitation of groundwater resources and the sustainability of development are guaranteed, and operators use technological methods to increase the efficiency of using water resources for more production in proportion to the amount tend to available water. In this article, first, the method of calculating the water allocated to the agricultural sector in the country has been studied and criticized. In this study, it was found that in the formula for calculating the current allocated water, the component of agricultural return water as an effective parameter causes a huge error in the calculation of allocated water. Then, a new formula for the calculation of allocated water was proposed, and an attempt was made to correct and apply the effect of the input component of agricultural return water on the amount of allocated water based on the calculation of allocated water in the new proposed method, taking into account the aquifer capacity based on the parameters of the water resources balance.

Firefighting services must provide a high rate of relief to ensure public safety. These rescue services are usually provided by vehicles stationed at fire stations. One of the most important issues in this regard is the location of these stations in the metropolitan area, so that they have the highest impact for emergency relief. To prioritize the five districts of Rasht to create or add new fire stations, five indices: area size, population, traffic, land usage and risk capability were considered as decision indicators. The statistical population for sampling was firefighters in Rasht. One station from each district and two firefighters from each district (10 firefighters in total) were selected as samples. The Questionnaire was used for data collection. Fuzzy AHP multi-criteria decision making method was used to rank areas of Rasht city. According to the results, the fourth zone with equal weight (0.305), first zone (0.210), fifth zone (0.174), third zone (0.173) and the second zone (0.136) were prioritized for construction of the new station, respectively.

This study sought to compare Iranian EFL teachers regarding their ethical beliefs at Iranian English language institutes and universities. To this end, first, the grounded theory method was used to conduct some interviews with 40 EFL teachers (20 male, 20 female). They were randomly selected from about 140 teachers working at institutes and universities in Fars province, Iran. After coding the obtained data, some categories were recognized, a model was designed, and exploratory factor analysis was conducted. The results confirmed the existence of social, collaborative, emotional, and managerial impacts. Then, a questionnaire was designed and developed based on grounded theory procedures, literature results, and the results of the qualitative studies. 140 EFL teachers filled it out and then the collected data underwent both descriptive and inferential statistics. The obtained results indicated that there was a significant difference between teachers regarding their ethical beliefs in universities and institutes. Moreover, it was revealed that the male and female teachers were significantly different. The mean scores of the female teachers and the male ones are 79.2500 and 75.2500 respectively. The findings of the current study can be useful for teachers, educators, teacher trainers, policymakers, and evaluators to make appropriate decisions and judgments.

The lack of water in arid and semi-arid areas has become a serious crisis, endangering living conditions. Sloping lands in the geographical and natural areas of Central Province have always been critical areas as sources of sediment production and erosion. Meanwhile, these areas provide valuable capacity for productive employment and conservation of water and soil resources through the construction of rain gardens in sloping lands with the help of rain catchment systems in the province. For this purpose, the amount and volume of annual rainfall, flood depth and discharge for different return periods, slope map, distribution of slope classes to the surface, and Curve number (CN) of the watershed for different return periods were obtained. Then, the development potential of rainfed gardens in the low yielding and sloping rainfed fields of Kabodkamar watershed in Adramand village was analyzed with the help of rain catchment systems. The results showed that, according to the slope and rocky nature of the area, the annual rainfall, depth and volume of runoff, and retention coefficient, the form of waterways, hydrological coefficients of the sub-watersheds, the area has the potential to use for rain catchment surface systems. In addition, considering the habitat and agro-ecological capacity of the region, water and soil resources, as well as the topography and geometry of the mentioned lands, the development of rainfed gardens is considered a key way to increase production and create employment along with ensuring the sustainability of the ecosystem in the region.

Studies show that chronic injuries like air pollution or acute damage such as hepatic ischemia-reperfusion (IR) cause various cellular pathologies such as oxidative stress, apoptosis, autophagy, and inflammation in hepatocytes. p-Coumaric acid (p-CA) is known as an antioxidant with many therapeutic impacts on inflammatory-related pathologies. In this experiment, we aimed to assess the hepatoprotective effects of p-CA on liver damage induced by dust and IR injury in adult male rats. 

Forty-eight adult male Wistar rats were divided into 6 groups; Control (CTRL); sham; DMSO+Dust+Laparotomy (LPT); DMSO+Dust+Ischemia-reperfusion (IR); p-CA+Dust+LPT; and p-CA+Dust+IR. Clean air, DMSO, p-CA, and dust were administrated 3 days a week for 6 consecutive weeks. Animals were sacrificed, the blood samples were aspirated and the liver sections were prepared for biochemical and histopathological assessments. 

Significantly (P<0.05), the results represented that dust and IR can potentially increase the levels of ALT, AST, direct and total bilirubin, triglyceride, and cholesterol in serum. Also, MDA, TNF-α, NF-κB, HMGB-1, and ATG-7 levels were increased in hepatocytes. Gene expression of Nrf2, HOX-1, IL-6, HOTAIR, and miR-34a showed an incremental trend in the liver tissue. Total antioxidant capacity (TAC) in hepatocytes was decreased following dust exposure and IR induction. Also, miR-20b-5p, MEG3, and SIRT1 in the liver were decreased in dust and dust+IR groups. 

p-CA alleviated pathological changes caused by dust exposure and IR injury. p-CA protected hepatic injury induced by dust and IR by inhibition of oxidative injury, inflammation, and autophagy.

One of the topics of curiosity in recent years in miscellaneous sciences such as physics and engineering is to attain analytical answers to evolution equations. In this work, a novel modification of the simplest equation method has been suggested to solve the nonlinear system of the partial differential equation. As an example, the proposed methods have been applied to achieve the exact solutions of the coupled generalized Schrödinger–Boussinesq system and Boussinesq-type coupled system. By giving specific values to the parameters, private answers are obtained and the plots of solutions are drawn. The newly-used method is highly accurate, flexible, effective, and programmable to solve systems of differential equations.

These days, regarding to advanced technologies, the use of ultralight aircraft for transportation and goods movement has been attended by industries and people. One of the major challenges for ultralight aircraft designers is related to reduction of engine vibrations. In this paper, determination of torsional damper for this aircraft engine types and their effect on reducing vibrations by combining three experimental, analytical and numerical methods are discussed. Starting with dynamic analysis and coding in MATLAB software, the system gas pressure and torque were validated with experimental results with less than 2% differences. Then the amount of angular displacement was validated at maximum rotating velocity with 1.86% difference by numerical and analytical methods, then the natural frequencies of system were obtained. Finally, the equation was extracted in order to determine the appropriate damping coefficient and its characteristics were determined. The results showed that using the damper reduces the system vibrations amplitude up to 40%.

The accelerating rate of urbanization and population growth in the past three decades in developing countries, especially in Iran, has brought many issues in social, economic and political aspects, and made it necessary to urban managers to prepare a comprehensive plan in the housing market. For such a program, assessing the housing indicators is a necessary tool to estimate the needs of housing sector in the country. Aim of this study is accomplish the spatial analysis of quantitative and qualitative indicators of housing in city of Izeh. Research method is theoretical-applied, based on the goals, and descriptive-analytical, based on data gathering. To measure the difference between the five regions of the city , 9 quantitative and qualitative indicators of housing have been applied. Then, after collecting information and statistical data, the fuzzy TOPSIS decision-making technique and GIS were used. In the fuzzy TOPSIS decision model, zones 2 and 3 with weights of 0.582 and 0.588 estimated as rich, zones 4 with weights of 0.392 and was semi rich, and zones 1 and 5 with weights 0.368 and 0.364 were poor. In general, the final result of this study shows the mismatch between the distribution of quantitative and qualitative indicators of housing in the regions of city of Izeh .

Theology (Kalam) is one of the Islamic intellectual sciences that has had proponents and opponents in Islamic sects since its inception. After compiling theological books, some agreed with this science and explained it, and some opposed it and criticized it. The Salafists, following the People of Hadiths (Ahl-alhdith), based on the extreme traditionalism and because of abandonment of rational reasoning, disagree with theology and consider it as a cause of damage and misguidance. Some of the most important arguments of the Salafists in denying and opposing theology are the avoidance of pious predecessors from the theological topics, prohibiting of Companions and Successors (Sahaba and Tabieen of the Holy Prophet) from dealing with theology, considering theology as heresy, its including superstitious, false, and even blasphemy, and the incompatibility between the results of theological discussions and Quran and tradition. The present study critiques and evaluates Salafi arguments and reveals their weaknesses through a documentary and critical analysis method. The arguments of the Salafists are typically fallacious and contradict the Qur'an and the tradition, as well as the manners of the companions, Successors, and other Islamic scholars. The Salafi view has bitter consequences such as the illegitimacy of other sciences and the rejecting of the value of intellectual and instrumental sciences, as well as a kind of exclusivism and absolutism about the understanding of the people of the first three centuries of the Islamic world.

In this paper, vibrations reduction of piston engine of ultralight aircrafts was studied with considering a combination of experimental, analytical and numerical methods. Analytical equations of dynamic absorber were obtained. Afterward, experimental test was used to determine the system torque. Due to the difficulty of obtaining experimental data, the amount of angular acceleration and then velocity and angular displacement were calculated numerically using MATLAB software and verified with experimental results with a difference of less than 2%. Different components of the system were designed with reverse engineering method using SolidWorks software. After data transmission to Adams software, vibrational analysis of the system was performed and validated with analytical results with a difference of less than 1.91%. A suitable dynamic absorber was selected. The results showed that engine vibrations is reduced up to 40%.

The aim of this study was to determine the strategies of human resources in implementing the strategy in the field of health through qualitative-quantitative method. The statistical population in the qualitative section was a group of deans of medical universities and senior managers of the Ministry of Health and Medical Education, and in the quantitative section were senior and middle managers of the staff of medical universities. In the qualitative part of the snowball sampling method, 20 people and in the quantitative part with the available sampling method, 20 people were selected as a statistical sample. Data in the qualitative part were extracted by performing Delphi technique with a semi-structured questionnaire in the first round and structured in the next rounds and in a quantitative part by performing a matrix questionnaire on a statistical sample and analyzed using SPSS and EXPERT CHOICE software. And analyzed. Qualitative findings showed that "human resource strategies" have six dimensions: and "strategy implementation" have three dimensions and nine components: There were structural dimensions, environmental dimension and behavioral dimension. The results of the quantitative section showed that in the strategies of supply and training of human resources, the component of macro environment, in the strategies of evaluating the performance of human resources and development and improvement, the component of the structure of the executive organization, in the strategy of compensation, the component of behavior In the employee participation strategy, the specific environment component has been of the highest importance.

One of the main organizational planning is human resource planning. The purpose of this study was to design a model for the implementation of human resource strategies in the field of health.

The combined research method and research design were also of the type of mixed exploratory research design. In the qualitative section, using the method of "samples contain rich information" with 20 heads of medical universities and senior managers of the Ministry of Health and Medical Education, using the Delphi method and using semi-structured questionnaires; Was interviewed. In the quantitative part of the research, a researcher-made questionnaire with multi-stage relative stratified sampling method was distributed among 334 senior and middle managers of the countrychr('39')s medical universities and the data were used by exploratory and confirmatory factor analysis. Analyzed with SPSS and AMOS software.

The results indicate that "human resource strategies" have six dimensions: 1. Human resource provision, 2. Training, 3. Performance evaluation, 4. Development and improvement, 5. Service reward and 6. Participation And "strategy implementation" has three dimensions and nine components as described: a- Structural dimension (1. structure of the implementing organization, 2. Capacities, 3. Resources), b- Environmental dimension (4. Macro environment, 5. Intermediate environment 6. Execution environment) and c- Behavioral dimension (7. Performers chr('39')behavior, 8. Target community behavior and 9. Developerschr('39') behavior). The results of the quantitative section showed that the impact of all dimensions of human resource strategies on the structural, environmental and behavioral dimensions of strategy implementation was confirmed.

Special attention to human resources, especially in organizations providing health services and health in the community as the most vital element of organizational success and creating a sustainable competitive advantage is always important in management.

The number of traffic accidents in the country is very worrying compared tomany countries in the world; Although the road factor has a lowerpercentage than the rest, but reducing road defects can reduce a significantnumber of accidents and, it should be noted in new studies that the aim ofthis study is also focused on identifying the effect of road structure failure onthe likelihood of traffic accidents. Due to the restriction of accurateinformation on traffic accidents and the possibility of removing the damagesand examining their cause, it has been tried to examine the effects ofroughness surface of the pavements on the behavior pattern and thedisplacement amount of urban bus drivers and the possibility of trafficaccidents from statistical point of view. In this study, in order to collect therequired information of drivers of public transport, using the opinions ofconsultants and also to study the research of the ancestors, a questionnairewith 4 scenarios was designed to analyze the factors affecting the probabilityof accidents and asked Yazd bus drivers to evaluate them based on theimportance of each parameter. Finally, in order to determine the effectivefactors and the relationships between these factors, is used factor andexploratory analysis. Application of this modeling provides analysis andstudy of the effect of various factors on the occurrence of accidents in thepublic vehicles. The results of this study show that the area and dimensionsof the damage (the amount of Ups and downs) has major effects fordetermining how drivers behave. The first reaction of drivers in the face offailure is not paying attention to the damage and crossing it. Damagesituation also with having the most factorto extent of 0/72 is one of one ofthe effective cases in the performance of public vehicles drivers. The mostinteraction effect between the variables, between the two options of suddenline change and save the line by changing the direction suddenly is with thecoefficient of interaction effect of 0/82.

Estimation of sediment load in rivers is one of the most important and applicable issues in studies and design of river and water engineering projects. Therefore, identification and suggestion of suitable methods for estimating suspended sediment load should be done based on relevant research. These methods include artificial neural network models, neurophysics, sedimentation rate curve as well as multivariate regression model. In this study, the efficiency of these methods was investigated in predicting discharge rate of suspended sediments of Gharachai River watershed. Daily time series data of measured flow discharge and sedimentation of bridge station of Gharachai River were used. The statistical period used in this model was two years (2016-2017). Independent variables used to enter the network include runoff and suspended load at the Gharachai River Doab Bridge station. The dependent variable, which is the network output, was the suspended load. After modeling with each compound and calculating RMSE and R2 values, the best combination was selected. The results showed that the neurophasic method based on discharge and sediment inputs and artificial neural network models based on discharge inputs were more accurate than multivariate regression and sedimentation rate curve. For values ​​higher the long-run mean of the statistical series, the values ​​simulated by the ANN model and for values less the mean and annual sediment load were also closer to the observed values. While for maximum values, no significant difference was found between ANN models, neurophysics, and linear regression.

The efficacy of impulse oscillometry as an indirect measure of exercise-induced airway changes, compared to spirometry has not been comprehensively appreciated. The objective was to compare airway responses to cold temperature exercise and to recognize whether impulse oscillometry parameters relate to spirometry parameters. 18 physically active men with probable Exercise-Induced Bronchospasm (Body Mass Index ≤25) were screened for this study. The exercise protocol was two 6-min sub-maximal exercises of running on the treadmill with 80-90% Peak Heart Rate in either cold (4.0 ◦C) or moderate (25.0 ◦C) temperature. 48 h was observed between these two challenges. Strong correlations were found between cold and moderate temperature data for impulse oscillometry and spirometry. Spirometry revealed post-challenge significant difference in cold and moderate temperatures (p<0.05). Respiratory resistance measured by impulse oscillometry found to be significantly different in post-challenge peak falls for two conditions. Significant correlations found within impulse oscillometry and spirometry data suggesting the efficacy of impulse oscillometry in evaluating airway responses to exercise challenges. Two challenges appeared to elicit Exercise-Induced Bronchospasm response by a similar mechanism of airway hyperresponsiveness and water loss.

The important role of risk and its challenges in organizations is one of the reasons for the importance of examining the risks of production. Considering the classification of the pharmaceutical industry as one of the most important industries, the investment risks in this industry have been analyzed using the Failure mode and effects analysis (FMEA) method. This method is one of the risk management techniques to identify, analyze, and ranking risk factors in order to increase the efficiency of the industry. This descriptive study suggests FMEA as a quantitative method for identifying production risks and, by computing risk priority numbers (RPNs), represents the probability of their risks and effects in the pharmaceutical industry. In this research, after identifying the risks of drug production through literature review and interviewing experts, a questionnaire was designed that out of 66 identified risks, 19 risks were identified and ranked by experts as important risks. Good manufacturing practices (GMP), exchange rate fluctuation, no marketing strategy and lack of proper estimation of market trends, inventories of raw materials and inventory of supplies was identified as the most important risks of drug production.

Gallic acid (GA) is a highly effective antioxidant, which its beneficial effects are well known, but its impact on expression of microRNAs (miRs) following hepatic ischemia-reperfusion (I/R) is not well recognized. Therefore, the current research was designed to specify the beneficial effect of GA on miRs (122 and 34a), liver functional tests, and histopathological alterations beyond I/R-induced hepatic injury. Thirty-two rats were randomly divided into four groups (8 per group) including: sham-operated (S), I/R, and GA+I/R pretreated groups. Rats in sham-operated group received physiologic saline (N/S, 2 ml/kg), on a weekly basis, once a day via intraperitoneally route), then a midline abdominal surgery was performed. IR, and GA+IR pretreated groups received physiologic saline (2 ml/kg), and GA (50, and 100 mg per kg) for same time, IP, respectively, before induction of transient ischemia. One hour after reperfusion, biochemical, and histopathological evaluations were performed and expression of miRs were evaluated. The results showed that GA reduced the concentrations of liver enzymes, miR-122, and miR-34a in serum, and preserved liver cells changes induced by I/R injury. These findings showed that GA has beneficial effect on liver damage induced by I/R. Therefore, it is suggested that GA can be administered as an anti-miR before elective hepatic surgeries for prevention of this complication.

Aging population is progressively increasing. Older adults suffer from the different chronic health conditions such as hypertension. Behavior change is a key strategy for effective hypertension management. Successful behavior change necessitates the adequate self-efficacy. This study aimed to evaluate the effects of a self-management program based on the 5 A's model on self-efficacy among the older men with hypertension. This randomized controlled trial was conducted in 2016–2017 on older men with hypertension in Ramsar, Iran. In total, 60 eligible participants were randomly allocated to an intervention and a control group. The participants in the intervention group were offered a self-management program based on the 5 A's behavior change model. Data were collected using a demographic questionnaire, a hypertension assessment form, the Self-Efficacy for Managing Chronic Disease Scale, and the hypertension Self-Efficacy Scale. Self-efficacy scales were completed for participants both before and 12 weeks after the intervention onset. The paired- and independent-sample t, Wilcoxon signed-rank, Mann–Whitney U, and Chi-square tests were used in the data analysis. The pretest mean scores of hypertension self-efficacy in the intervention and the control groups were, respectively, 48.62 ± 11.71 and 44.65 ± 15.4, which significantly increased to 79 ± 13.13 and 62.06 ± 15.38 at posttest (P < 0.001). Moreover, the pretest mean scores of chronic disease management self-efficacy in these groups significantly increased from, respectively, 5.64 ± 1.28 and 5.35 ± 1.40 at pretest to 8.05 ± 1.29 and 6.12 ± 1.48 at posttest (P < 0.001). The pretest–posttest mean differences of the mean scores of both types of self-efficacy in the intervention group were significantly greater than the control group (P < 0.001). The self-management program based on the 5 A's model is effective in significantly improving the self-efficacy among older men with hypertension.

Portfolio selection problem is one of the most important economic issues. The right combination of stock or other asset portfolio is that an investor pays to buy it. Selection of an optimal portfolio is based on the principle that the investor decides to accept one or several investments among different investment depending on the tolerance of risk and expected a reasonable amount of stock returns. In this study, improved Non-Dominated Sorting multi-objective genetic algorithms and Evolutionary Algorithm Strength Pareto are used to create an optimum portfolio. These algorithms are improved version of their previous versions and have a better solution than its previous versions. The value of the portfolio and its risk, as optimization purposes and conditional value at risk as the basis risk, have been used. Two applied conditions consider to Portfolio and shown that the Evolutionary Algorithm Strength Pareto has better results than the Non-Dominated Sorting Genetic Algorithm II.

?The purpose of this paper is to using the Simulated Annealing method to solving a linear equations system which have an ill-conditioned coefficients matrix?. ?A linear equation system is called ill-conditioned if its condition number be large?. ?By using a matrix scaling?, ?the linear equation system transforms into a linear equation system with less condition number?. ?Matrix balancing is performed by Simulated Annealing algorithm?. ?The efficiency of this method is investigated by numerical examples?. ?Numerical results show that Simulated Annealing can reduce the condition number of equations?.

In the dynamic manipulation of objects, the aim is to throw an object by a robot to the desired target even outside the reachable workspace. In this paper, the concept of the throw-able workspace or dynamic manipulation workspace is defined as a set of points which the robot is able to throw the object at them. Thus, in order to obtain the maximum dynamic manipulation workspace which means the farthest points that object can be manipulated, it is necessary to solve the optimal throwing problem. To this end, the optimal throwing problem is defined as the optimal control problem solved using the indirect solution method based on the fundamental theorem of the calculus of variations. By applying the throwing equation as a moving boundary condition, the derived optimality conditions construct a two-point boundary value problem which its solution results in the optimal throwing. Finally, an algorithm is presented to calculate the maximum dynamic manipulation workspace. Then, simulation results are presented for a single link robot in order to evaluate the defined concept as well as the effectiveness of the proposed method for problem-solving.

Large-scale projects often have several activities which are performed by subcontractors with limited multi-resources. Project scheduling with limited resources is one of the most famous problems in the research operations and optimization cases. The resource-constraint project scheduling problem (RCPSP) is a NP-hard problem in which the activities of a project must be scheduled to reduce the project duration. Therefore, subcontractors of the construction projects join together to decrease the project time and finally increase the project profit. This is an incentive for the subcontractors to form coalitions. This study presents a model based on the resource leveling problem. Results of the proposed model show that the subcontractors can earn more profit by the cooperation rather than working individually. Moreover, it is demonstrated that techniques such as the Shapley Value, Max-Min Core, and Equal Profit Method are able to fairly allocate extra profit of the cooperation among the subcontractors.

Air transport system has always been involved in all aspects of life because of its high potential in transporting passengers and goods. In this research we surveys the effects of travel variables on demand of domestic air transport, and for gathering required information from passengers, a questionnaire was designed including 20 effective parameters on air transport demand with questions These parameters were investigated based on their importance using “Factor Analysis” and finally proved that the factors “price paid by passengers”, ”services offered by air transport system” and “time” has had the greatest impact on air transport demand with more than 20 % influence. “Structural Equation Modeling” has been used for checking the “Factor Analysis” results. The results of the model proved the correctness of factor analysis. Furthermore, the result of factor analysis has showed that the most important parameter has been “low cost travel” with the factor load of 0.9-1 in all case studies. Results show that both groups with factor load of more than 0.5 in the obtained factors have identified the factor “services” as the important and effective factor with the influence value of more than 20%.