sima saravani

The purpose of the current study was to examine the effect of hydroalcoholic extract of Psidium guajava plant on bone marrow cells in rats and it will be extended to humans. Guava plant leaves were collected from Chabahar region in Sistan and Baluchistan province and dried. 40 adult male rats were assigned to one control group and three experimental groups (subjects that were administeredhydroalcoholic extract of P. guajava leaves with respective doses of 3000 mg/kg, 4000 mg/kg, or 5000 mg/kg, for 3 months, once daily). Following the intervention period, blood was taken from the heart and bone marrow was taken from the femur. Several parameters such as cell blood count, hemoglobin, and hematocrit, were examined in the blood sample. Also, in the bone marrow sample, a relative count was performed on five hundred bone marrow cells and the ratio of myeloid to erythroid was determined in both control and experimental groups. The results of this study indicated that the hydroalcoholic extract somewhat increased white blood cells and red blood cells, but no significant change was observed. The result of the study revealed the positive effects of guava leaf extract may be due to flavonoids, quercetin and triterpenes, which strong antioxidants that can prevent damage are caused by free radicals destroying cells. This study shows that guava leaf extract can have a positive effect on hematological parameters, as well as the lack of mutagenicity and cytotoxicity in high doses of this plant extract rather reflects its safe use in traditional medicine. Therefore, it is recommended that guava leaf extract be considered as a complementary and alternative treatment for many diseases, including the treatment of anemia.

Urinary tract infection is one of the most common asymptomatic infectious diseases during pregnancy, which is mostly caused by Escherichia coli infection, which, if not diagnosed and treated, causes harm to the mother and the fetus.

In a cross-sectional study of 50 pregnant women who referred to the outpatient clinic of Zabol hospital center after completing the questionnaire and examining the patients by obstetrician and gynecologist and ensuring that they were healthy, a sterile mid-stream urine sample was prepared and examined and diagnosed in terms of a complete urine test and placed were and Escherichia coli samples were separated from other colonies by diagnostic tests. The characterization of ZnO-NPs was performed by, Fourier-transform infrared spectroscopy, scanning and transmission electron microscopes, and X-ray diffraction.  The antimicrobial activity of ZnO-NPs synthesis in Eucalyptus was studied both in vitro against E. coli clinical isolates from woman.

The results of the analyzes showed that the zinc oxide nanoparticles were synthesized in a polyhedral to round shape and the size of the nanoparticles was 21 nm. The results of the antibiotic resistance pattern investigation showed that the most sensitive to the antibiotic amikacin was and also the minimum inhibitory concentration of synthetic zinc nanoparticles was equal to 1500 μg/ml.

In this study, it was found that aqueous extract of Eucalyptus leaves has the ability to produce zinc nanoparticles oxide nanoparticles have been synthesized from zinc sulfate, and the synthetic nanoparticles have shown good antimicrobial properties against antibiotic-resistant Escherichia coli bacteria.

Extraction by conventional methods such as Soxhlet requires a long time and the possibility of damage to heatsensitive compounds.

In this study, modern ultrasoundmethods used to perform and investigate the antibacterial properties of plant extracts were compared.

The extracts of Mentha piperita, Rosmarinus officinalis, and Withania somnifera were prepared by an ultrasound device. Ten Escherichia coli strains were isolated from poultry stool samples. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) plant extracts against E. coli were determined using the microdilution method.

The results showed that the lowest inhibitory concentrations of rosemary, peppermint, and wind cheese extracts prepared by ultrasound were equal to 3.1 mg/mL, while the highest inhibitory concentrations of these extracts were equal to 25, 25, and 50 mg/mL, respectively. The lowest lethal concentrations of rosemary, peppermint, and wind cheese extracts were 6.25 mg/mL, while the highest inhibitory concentrations of these extracts were 25, 25, and 50 mg/mL, respectively. The lowest bactericidal concentrations of rosemary, peppermint, and wind cheese extracts prepared by ultrasonic waves were equal to 6.25 mg/mL, while the highest lethal concentrations of these extracts were equal to 50, 25, and 100 mg/mL, respectively.

According to the findings of the study, it can be concluded that the use of ultrasonic waves is a fast, effective, and economical method for extracting plant components. In addition, the methanolic extract of peppermint has the most inhibitory and lethal properties.

 Escherichia coli (Gram-negative bacilli) inflicts large economic losses on the poultry industry and is one of the most important causes of poultry diseases. The indiscriminate use of antibiotics has contributed to today’s increasing prevalence of drug-resistant strains, which their emergence appears to exceed the discovery of new drugs. Therefore, several attempts have been dedicated to find new compounds as effective alternatives to antibiotics. Medicinal plants constitute a rich source for various antimicrobial compounds.

 The aim of this study was to evaluate the antibiotic resistance trend of the E. coli strains isolated from Quail feces samples and to investigate the antimicrobial effects of Eshvarak extract against these strains.

 Eshvarak plant was collected from Saravan (Sistan and Baluchestan province, Iran) and identified in the botany laboratory of Zabol University. E. coli samples were isolated from poultry feces. Various solvents (methanol (100%), ethanol (100%), water (100%), hydro-alcohol (70%), and ethyl-acetate (100%)) were used to prepare Eshvarak extract. Inhibitory zone diameter was determined in an agar-based medium using a standard procedure. The MIC and MBC of prepared extracts were determined by the micro-dilution method.

 The lowest MIC values were obtained for the methanolic (12.5 ppm), ethanolic (12.5 ppm), aqueous (12.5 ppm), hydroalcoholic (25 ppm), and ethyl-acetate (12.5 ppm) Eshvarak extracts. The highest inhibitory zone diameters against E. coli were recorded at the 100-ppm concentration of the methanolic (8 mm), ethanolic (7 mm), aqueous (8 mm), hydroalcoholic (10 mm), and ethyl-acetate (5 mm) Eshvarak extracts.

 Eshvarak extract, particularly in the hydroalcoholic solvent, inhibited the growth of E. coli. However, the antimicrobial properties of plant extracts seem to be independent of the extraction method or the type of solvent.

Today, opportunistic fungi, especially Candida albicans, are among the most common risk factors in patients with weakened immune systems. Fungal infections caused by Candida species and increasing number of azole-resistant strains are of great importance in immunocompromised patients. The toxicity of the drugs used, the development of resistance to these fungi, and the problems caused by drug interactions necessitate the use of more effective drugs with less toxicity. This study aimed to evaluate the antifungal activity of medicinal plant extracts on C. albicans. In this review study, Scopus, PubMed, MEDLINE, Google Scholar, SID, and Magiran databases were searched between 2000 and 2019 to identify related articles. The search keywords were “Candida albicans”, “Complementary”, “Herbal medicine” and their Persian equivalents. All in vivo and in vitro trials were included in the study. The reviewed studies showed the effectiveness of some compounds in inhibiting the growth of C. albicans. The results of the present research were in in-vitro conditions, but they need to be conducted in-vivo for human use.

Application of plants and their compounds has long been significant in treating diseases mainly due to their natural potential and lower side effects than chemical drugs and presence of alkaloids, and polyphenols in their extract. Despite research carried out on the properties of such plants and popularity of blood diseases, few studies have been done on its effects on blood cells, thus, it was attempted for the first time to evaluate the effect of hydroalcoholic extract of the Pseudium guava leaf on blood cells in rats.

After extracting the leaves of guava plant, 40 adult male rats were divided into four groups. Which included control (cases with no treatment during the study) and experimental groups (cases receivied of hydroalcoholic extract of Psidium guava leaf, in different doses daily for 3 months). At the end of the test period, blood samples were counted.

The results of this study showed that the hydroalcoholic extract increased White Blood Cells and Red Blood Cells, but no significant change was observed. This increase in hematocrit was significant in the group receiving hydroalcoholic extract at a dose of 5000 mg/kg compared to the control group.

The results of the study had a positive effect on blood cells. Also, the lack of cytotoxicity with high doses of the extract of this plant means its safe use in traditional medicine.

Strategic thinking is one of the most influential factors on organizational performance. However, due to a lack of studies in this area, it is not possible to understand the impact of strategic thinking on the performance of community-based health organizations. The purpose of this study was to investigate the impact of strategic thinking and its components on organizational performance of Zabol University of Medical Sciences staff.

This is an applied and correlational study. 169 employees were selected by simple random sampling. Data were collected using two strategic thinking questionnaires and a performance evaluation questionnaire. Data were analyzed using SPSS 20 software and linear regression test.

Strategic thinking and its components have a positive impact on organizational performance of Zabol University of Medical Sciences staff. Among the four components of strategic thinking, the most influential was foresight, followed by goal-focused, systemic thinking, and clever opportunity.

The results of this study showed that strategic thinking and its components have a positive and significant effect on organizational performance improvement of Zabol University of Medical Sciences. We suggested that infuture studies other factors that may affect organizational performance should be considered simultaneously with strategic thinking.

The mortality rate, which is by itself under the influence of various social and economic factors, can be considered as one of the most important indicators of the development and health of any country. Therefore, identification of past and present changes in mortality and factors which can increase life expectancy in the future seems to be of paramount importance. Therefore, the present study was conducted to identify the causes of death and mortality rate in patients admitting to Amir Almomenin hospital in 2016. The present cross-sectional study was conducted to identify the causes of death and mortality rate in patients referring to Amir Almomenin hospital in 2016. Required data was collected using a questionnaire and, then, processed by SPSS 16l then, the collected data was analyzed using descriptive statistics methods such as frequency percentage, rates and chi-square tests. Out of 200 patients deaths occurred in Amir Almomenin hospital in 2016, 165 cases were male and 115 cases were female. In regard of age groups, 70-79 years with 101 deaths, 89-80 years with 54 cases, and 20-29 years with 20 cases turned out to be the most frequent ones. The highest mortality rates were observed in two departments of emergency with 94 and ICU with 64 cases; the least frequent was the CCU department with only 11 cases. Much more attention requires to be pair to prevention of accidents and causes of internal disease and ischemic diseases in order to increase life expectancy and trying to reduce various risk factors; additionally, considering the results of the present study and the high number of deaths due to accidents, especially in men, it seems that more efficient interventions are needed for age groups at risk and for men.

This study was investigating the effect of electromagnetic wave generated by mobile and base transceiver station (900 MHz) on liver enzymes in both mature and immature female age. In this study, 20 rats Sprague Dawley white mature female age 8 to 9 weeks and weight 180 to 200 g and 20 rats immature age 3 to 4 weeks, weight 80 to 100 g, each age group were randomly divided in two groups (control and test). Test groups, were daily for four hours and four different times exposed to electromagnetic waves with signal generator (900 MHz), 5-meter intervals. Control groups were kept at equal condition (themperature and light) in laboratory during experiment. After at the end experimental period, blood was collected by heart puncture of all animal. Exposure to EMF generated by BTS had significant effect on liver enzymes composition in mature and immature rats. AST, ALT and ALP in immature-test groups decreased significantly compared with their respective control groups (p<0.05). ALP in mature-test groups increased significantly compared with their respective control groups (p<0.05). These result suggest that exposure to EMF generated by BTS has a deleterious effect on liver enzymes and that this effect is more sever in immature animals.