yalda taghipour

Considering the spread of Covid-19, it is important to know its complications. In the present study, we examined the frequency of patients with myocarditis and Kawasaki disease and related demographic and laboratory findings in children before and during covid-19.

The present study was carried out in a descriptive-analytical manner on patients with myocarditis or Kawasaki disease during the years 2016 to 2016. During this study, demographic information, laboratory variables of the child were collected from the patients' files and statistically analyzed using SPSS version 24 software.

In this study, 65 patients (31 girls and 34 boys) with an average age of 41.28 ± 3.9 months were examined. Of these, 46 people (69.7%) had Kawasaki disease and 19 (28.8%) had myocarditis. The condition of being infected with Covid-19 was also observed in 22 of the patients (33.3%). The rate of hospitalization with the diagnosis of Kawasaki disease after Covid-19 was significantly higher than before [27 cases (58.7%) against 19 cases ( 41.3%)], while the hospitalization rate with the diagnosis of myocarditis decreased significantly after the onset of corona [1 case (5.3%) vs. 1 case (5.3%), (P<0.001)].

According to the results, the hospitalization rate with the diagnosis of Kawasaki disease after the occurrence of covid-19 was significantly higher than before, and the frequency of patients with Kawasaki disease with and without covid-19 was not significantly different.

Seizure is a common sign in neonates hospitalized in the neonatal intensive care units (NICU) that may lead to morbidity and mortality. Most neonatal seizures are subclinical. Conventional EEG (cEEG) is the gold standard for detecting and monitoring seizures but is not widely available. Amplitude-integrated electroencephalography (aEEG) has been used for over a decade to evaluate infants with seizures. In this study, we tried to determine the efficacy of aEEG as
a widely available diagnostic tool in diagnosing seizures.

All cases with seizures or suspicious seizures were admitted to the NICU of the Children’s Medical Center for one year. cEEG and aEEG were performed for these infants. aEEG was recorded for at least six hours with a description of the tracing. Clinical information, outcomes, and questionnaires (patient information) were recorded in detail. The obtained data were analyzed with the SPSS version 24 software.

Eleven out of twenty-five aEEG recordings were abnormal; other patients showed normal aEEGs. The most common clinical and neurological manifestations were seizure (68%) and hypotonia (28%); the mortality rate was 12%. No significant correlation was observed between aEEG findings and gender, age, familial relation, outcome, ultrasound result, type of seizure, and underlying disease.

Abdominal colic during infancy is a common complaint of parents within the first three months after the child’s birth. As the intestinal microflora in these infants is different from non-colic newborns, we aimed to determine the effects of probiotics on the balance of intestinal microflora and reducing restlessness in infants with colic. This randomized clinical trial was performed on 44 breastfed infants (20-60 days old), with a birth weight of > 2500 g, suffering from colic, based on Wessel’s definition. These infants received 1-5 drops of placebo (label 1) per day for five consecutive days. Afterwards, they were administered 2-5 drops of Lactobacillus reuteri (label2) (17938 DSM) per day for 14 consecutive days. The parents were contacted twice on a daily basis and the duration of cramps and restlessness in infants was recorded and evaluated (IRCT=2014012713489). Among 44 infants, 36 cases completed the study. The mean period of restlessness after 5 days of receiving placebo and L. reuteri was 275±142.8 and 172±88.3 min, respectively (p<0.001). Also, after 14 days of L. reuteri administration, the mean period of restlessness was 106±53.67 min. The results showed that probiotic L. reuteri reduced crying and restlessness duration in infants with colic.