depression

Depression is a problem that causes many problems in students, and these problems prevent the development of their talents, and depressed students are usually not interested in studying and this affects their academic performance.

The present study was conducted with the aim of comparing the effectiveness of the educational package based on the acceptance and commitment approach with meaning therapy on the academic vitality of depressed second-year high school students.

The research method was semi-experimental with a pre-test-post-test design and a control group with a three-month follow-up period. The statistical population included the depressed students of girls' high schools in the second year of high school in Khomein city, who had referred to the counseling and psychological center of education management in Khomein city in the academic year of 2022-2023. 45 people, as a sample, were randomly selected in 3 groups of 15 people (two experimental and control groups) using the purposeful sampling method. The academic vitality questionnaire (Dehghanizadeh and Hosseinchari, 2013) was used to collect data. Also, the educational package based on the approach of acceptance and commitment was developed by the researcher and the meaning therapy protocol of Hotzel (2002) was used for the intervention. The data were analyzed using repeated measure analysis of variance with Spss26 software.

The results showed that the educational package based on acceptance and commitment and meaning therapy could increase the scores of depressed students in academic life (p<0.01) and the effectiveness of therapy based on acceptance and commitment was more than meaning therapy.

It can be concluded that the educational package based on acceptance and commitment is a more effective approach in promoting academic vitality in depressed students and it is important to pay attention to this point in the treatment of depression in students.

The objective of this study was to identify patients' experiences with neuroscience-based cognitive therapy methods and examine their impact on various psychological, emotional, cognitive, and physical aspects.

This research used a qualitative approach and a semi-structured interview design. The sample included 23 patients from Tehran, selected through purposive sampling. Data collection was conducted through individual interviews using a structured interview protocol, and data analysis was performed using Nvivo software and thematic analysis.

The results indicated that neuroscience-based cognitive therapies led to significant improvements in patients' emotional and psychological experiences. Participants reported reductions in stress, increased relaxation, and improved relationships with their therapists. Additionally, physical changes such as reduced chronic pain, improved sleep quality, and increased energy levels were reported. Cognitively, patients experienced increased self-awareness and improved problem-solving and decision-making abilities.

This study demonstrates that neuroscience-based cognitive therapies can have positive effects on improving patients' psychological and physical conditions. Patients' experiences highlight the effectiveness of these methods in reducing stress, enhancing cognitive and physical functioning, and improving overall quality of life.

The present study was conducted to predict suicidal ideation based on the brain-behavioral systems with the mediating role of emotion regulation in depressed patients. The present research method was the descriptive-correlation type of structural equation modeling. The statistical population of the present study consisted of all women with depression who were referred to the psychological clinics of Tehran in 2022, from which 320 people were selected by non-random and available sampling methods. To measure the research variables, Beck et al.'s Beck Depression Inventory-II (BDI-II, 1996), Beck et al.'s Beck Scale for Suicide Ideation (BSSI, 1979), Carver and White's Behavioral activation systems/Behavioral inhibition systems scale (BIS/BAS, 1994), and Gross & John's Cognitive Emotion Regulation Questionnaire (CERQ, 2003) was used. The obtained data were analyzed using Pearson's correlation coefficient test and structural equation modeling. The results showed that there is a negative and significant relationship between the behavioral activation system and emotion regulation with suicidal ideation (P<0.01). There is a positive and significant relationship between behavioral inhibition systems and emotion regulation with suicidal ideation (P<0.01). Other results indicated the confirmation of the mediating role of emotion regulation in the relationship between behavioral brain systems and suicidal ideation in depressed patients (P<0.01). Also, the results showed that the proposed model had a good fit. Therefore, it is necessary to pay attention to the regulation of emotion and brain-behavioral systems in preventing suicidal thoughts in psychological programs and interventions.

The purpose of current study was to the effect of marital satisfaction on self-compassion: The mediating role of depression in married individuals in Isfahan city. The research method was descriptive with correlation type and path analysis. The statistical population of the research consisted of all the married people in Isfahan city in 2018 and the statistical sample of the study was 200 people, chosen by convenience non-random sampling method. Index of Hudson's marital satisfaction (1992), Beck's et al (1998) depression questionnaire, Neff's self-compassion questionnaire (2003) were used to collect information. SPSS16 and AMOS16 were used to analyze data. The results showed that there is a significant positive effect between self-esteem and marital satisfaction (P <0.01) and a negative significant effect between self-esteem and depression (P <0.01). Also, the self-esteem variable has a positive effect on marital satisfaction indirectly through depression (P <0.01). The model obtained for all three research hypotheses was also well-fitted (P <0/01). According to the findings of the study, self-compassion can be one of the best ways to establish a relationship with oneself and others, and by preventing the avoidance of painful thoughts and emotions in times of interpersonal conflict, it causes couples to share their experiences and emotions. Be more receptive, more attentive, and more compassionate.

Stem cells play an important role in tissue regeneration and disease treatment, so the present study was conducted with the aim of investigating the effect of cell therapy on increasing serotonin secretion in depression by cells.

This research was practical in terms of its purpose and in terms of experimental implementation with a pre-test and post-test design with a control group. The statistical population of the research was adult Syrian rats, known as Syrian rats. 40 Syrian rats were purposefully selected as samples based on the research entry criteria, and were randomly divided into two experimental and control groups (20 in each group). First, the blood serotonin levels of the two groups were measured. Then the test group received umbilical cord stem cells through injection and at this time the control group did not receive any intervention. After receiving the stem cells, the level of serotonin secretion in the two groups was re-examined, SPSS version 25 Software and un ivariate covariance analysis were used in the data analysis.

The results showed that by controlling the effect of the pre-test, there was a significant difference between the average post-test serotonin secretion in the experimental and control groups (p<0.01), so cell therapy increases the serotonin secretion in depression by cells. It has become fundamental.

Stem cells can be considered promising for the treatment of cognitive and mental diseases and new developing strategies for the treatment of nervous system diseases including depression.

Behavioral inhibition and activation systems explain changes in a person's mood and behaviors based on contextual factors, and therefore individual differences in sensitivities lead to differences in processing. In addition, rumination as a sustained response style is closely related to the maintenance of major depressive disorder and is an maladaptive pattern of focusing on negative thoughts and feelings. Considering the impact of depression on emotional, physical, and cognitive dimensions, it can cause problems in attention, memory, and cognitive control in affected people, therefore, more research on cognitive control in depressive disorder is needed.

This study aimed to investigate the structural model of inhibition and behavioral activation system and cognitive control and flexibility with adolescent depression with the mediating role of rumination.

This research was fundamental in purpose and a descriptive-correlational study of the structural equation modeling method. The statistical population of this study consisted of all high school students in Tehran who are studying in the academic year 2023-2024. The sample consisted of 347 Tehran students selected by cluster sampling. To collect data, the Rumination Questionnaire of Nolen et al. (1991), the Hospital Anxiety and Depression Scale of Zigmond and Snaith (1983), the Inhibition and Behavioral Activation System Questionnaire of Carver et al. (1994), and the Cognitive Control and Flexibility Questionnaire (CCFQ) of Gabrys et al. (2018) were used. To evaluate the proposed model, structural equation modeling and AMOS.24 and SPSS. 27 were used.

The results of the Pearson correlation coefficient showed a significant relationship between behavioral activation system, cognitive control, and flexibility with rumination depression (P< 0.05). The findings indicate that the proposed model is appropriately fit with the data. The results of structural equation modeling showed that in the model, 20% of the variance in rumination drowning is explained by cognitive control flexibility and inhibition and behavioral activation system. Finally, 29% of the variance of depression is explained by cognitive control and flexibility, inhibition, behavioral activation system, and drowning in rumination.

According to these findings, the use of therapeutic interventions that provide the basis for psychological flexibility and cognitive control can help reduce rumination and depressive symptoms.

the goal of this study was to evaluate the Comparison of the effectiveness of cognitive-behavioral therapy and quality of life therapy on depression in adolescents. The present study is applied in terms of experimental method in the form of a pre-test design, post-test with the control group and interventio. The research instruments included Beck Depression (1996- BDI-II). For this purpose, 30 students who scored above 20 in the Beck depression test were randomly selected by multi-stage cluster sampling method. Then, the cognitive behavioral test groups received therapeutic interventions in 8 sessions and the quality of life therapy group in 10 sessions. The data were analyzed using the statistical method of analysis of covariance. The findings show that depression has decreased significantly in both experimental groups, but in terms of preference, the superiority of a particular treatment over another was not seen in this study, which means it cannot be said which one is more effective. According to the findings of this research, it can be said that cognitive behavioral therapy and therapy based on quality of life are useful as effective intervention methods to reduce depression and increase quality of life.

The aim of the study was to investigate the mediating role of self-esteem in the relationship between mindfulness with anxiety and depression. The research design was correlational. Among the undergraduate and graduate students of Tehran South Branch, Islamic Azad University, who were studying in 1402-1401, 336 people selected as the sample group using convenient sampling method. Data were collected using the Mindful Attention Awareness Scale (Brown and Rayan, 2003), the Self-esteem scale (Rosenberg, 1965), the Beck Anxiety Inventory (Beck et al., 1988), and the Beck Depression Inventory (Beck et al., 1961). The proposed research model investigated using structural equations. The results obtained from the structural equations showed that the coefficients of the path of mindfulness with anxiety and depression were significant and were -0.501 and -0.282, respectively. In addition, the indirect path of mind- fulness with anxiety and depression due to self-esteem was -0.120 and -0.281, respectively. Therefore, the mediating role of self-esteem in the relationship between mindfulness with anxiety and depression confirmed. Based on the obtained results, anxiety and depression could be reduced by applying mindfulness and focusing on the role of self-esteem and strengthening it.

The aim of this study was effectiveness of problem solving training on depression and anxiety of adolescent students during the Corona virus era. This research was a quasi experimental type with a pretest-posttest design and followup with a control group. 30 teenage students were selected by purposive sampling method and randomly assigned to experimental and control groups (15). The problem solving training program was implemented in 10 one-hour sessions on the experimental group for measured using to Depression Questionnaire (Beck, Steer & Brown 1996) and Anxiety Questionnaire (Beck, Spstein, Brown & Steer, 1988). The data was analyzed through the method of Mixed ANOVA and it showed that there was a significant difference in the mean scores of the participants in depression and anxiety in the posttest compared to the pretest. There was no significant change between the posttest and follow-up scores in the depression and anxiety of the students in the experimental group, which indicated the significant persistence of the changes in the follow-up phase. Results showed necessity of using the problem solving training program for teenagers in order to cope effectively in critical situations.