medicinal plant
در نشریات گروه محیط زیست-
International Journal of Advanced Biological and Biomedical Research, Volume:13 Issue: 3, Summer 2025, PP 254 -269Background
Shallot with the scientific name Allium hertifolium Boiss is one of the best-known plants in the Alliaceae family. In Iran, shallots have been used as food and medicine for a long time. Most chemical and biological studies on garlic and related Allium species have indeed predominantly focused on sulfur compounds because of their notable health benefits. Recently, however, there has been increasing interest in saponins. These water-soluble compounds are notable for their stability during cooking, which makes them particularly interesting for their potential health benefits. Saponins are being studied for their antioxidant properties, as well as their potential roles in reducing inflammation and boosting immune function. The main objective of this review was to evaluate some medicinal properties of Allium hirtifolium Boiss.
MethodTo gather comprehensive information on Allium hirtifolium, the details on used plant parts were collected, therapeutic properties, pharmacological effects, indications, and dosage forms from data collection, library sources, written articles, and reference books. Further information, such as the plant’s form and description, planting methods, and planting times, was obtained through firsthand experience by cultivating seedlings at the Kohgiluyeh and Boyer-Ahmad Agriculture and Natural Resources Research and Education Center. This approach provided a well-rounded understanding of the plant’s uses and cultivation requirements.
ResultsThe biological activity of A. hirtifolium has been known since ancient times. Babylonians, Egyptians, Phoenicians, Greeks, and Romans used garlic as a remedy for intestinal diseases, respiratory infections, skin diseases, bacterial infections, worms, wounds and tumors. The effect of A. hirtifolium may be due to its antibacterial properties or its ability to block the formation of carcinogenic substances, halve the activation of carcinogenic substances, improve DNA repair, reduce cell proliferation or induce cell death. Epidemiological studies have shown that increased consumption of Allium spp. reduces the risk of prostate and stomach cancer, and this has been linked mainly to two main classes of compounds: the apolar sulfur compounds and the polar saponins. The compounds contained in A. hirtifolium have various beneficial biological effects such as antibacterial, antioxidant, and anti-diabetic. Naringenin is the most important compound among the flavonoids, which has various pharmacological activities. In addition, the constituents of this plant play various roles in modulating signaling pathways to prevent cancer, diabetes, and heart disease. Thus, A. hirtifolium and the compounds contained in this plant may be promising candidates for various diseases due to their diverse pharmacological activities.
ConclusionAllium hirtifolium, a medicinal plant collected from natural habitats in Iran, is extensively utilized by the local population and in traditional medicine. It is valued for its anti-hemolytic effect, making it a suitable herbal supplement in human nutrition. The therapeutic benefits of A. hirtifolium are largely attributed to its antioxidant activity, which helps scavenge free radicals. By neutralizing these harmful agents, the plant may contribute to the prevention of various diseases associated with oxidative stress.
Keywords: Antioxidant, Cancer, Medicinal Plant, Saponins, Shallot -
Artemisia annua, a medicinal plant with a history dating back over two millennia, has been recognized in ancient Asian and European medical texts as a remedy for a wide range of ailments. The World Health Organization (WHO) has endorsed this plant for the treatment of malaria. Traditionally, decoctions of the whole plant have been used to treat diseases such as malaria, cough, and cold. The dried leaf powder is employed to treat diarrhea. The entire flowering plant exhibits a multitude of therapeutic properties, including anthelmintic, antipyretic, antiseptic, and digestive aid. In addition, it can invigorate the body and improve gastric function. Artemisia annua contains a highly significant compound, artemisinin, which serves as the primary constituent of medications used globally to treat malaria. Furthermore, research has demonstrated artemisinin's ability to eradicate breast cancer cells. Tea prepared from Artemisia annua is utilized to manage HIV/AIDS. Recent scientific studies have extensively investigated the plant's antiviral effects on the HIV virus. Given the widespread prevalence of AIDS worldwide, these studies hold immense importance. Through this review, we aim to illuminate the significance and therapeutic applications of Artemisia annua. It is our hope that this study will contribute to a deeper understanding of this plant and its role in promoting public health.
Keywords: Artemisinin, Chemical Composition, Malaria, Medicinal Plant, Therapeutic Indication -
به منظور بهینه سازی گیاه دارویی نسترن وحشی (L canina Rosa).به عنوان مهمترین پایه گل رز و نیز با هدف دستیابی سریع به کالوس مناسب جهت استفاده از مزایای ویژهی آن، تحقیق حاضر انجام پذیرفت. بدین منظور، آزمایشی به صورت فاکتوریل در قالب طرح پایه کاملا تصادفی با دو فاکتور محیط کشت (2.1 MS و 4.1 MS)و غلظتهای مختلف توفوردی (1 ،0 ،2/5 ،0 و 2/2 1-mgL) در چهار تکرار انجام شد. قطعات گره دار 1.5 سانتیمتری از قسمت میانی شاخه های فرعی میانه تاج درختچه ای در مرحله میوه دهی تهیه شدند. ارزیابی نتایج، یکماه پس از کشت، بر اساس تغییر شکل (آمادگی برای ورود به مرحله تولید کالوس) و کالوسزایی ریزنمونه ها صورت پذیرفت. نتایج نشان داد که بیشترین درصد ریزنمونه تغییر شکل یافته مربوط به 0/5 MS بوده است. غلظت چهار 1-mgL توفوردی، بیشترین درصد ریزنمونه تغییر شکل یافته در ناحیه اطراف جوانه و غلظت 2/5 1-mgL آن، بیشترین درصد ریزنمونه تغییر شکل یافته در دو سر و سرتاسر ریزنمونه را نشان دادند. همچنین، بیشترین درصد ریزنمونه کالوسزا در یک سر و دو سر ریزنمونه در تیمار فاقد هورمون مشاهده شد. بیشترین وزن تازه و خشک کالوس متعلق به غلظتهای بیشینه توفوردی و تیمار 0/5 MS حاوی 2/5 1-mgL بود. پدیدار شدن کالوس در قاعده برگچه های متصل به محور برگ گیاهچه های درون شیشه ای (همزمان با زرد شدن برگ) مستقر بر ریزنمونه تنها متاثر از کاربرد توفوردی نبود. ظهور این پدیده به احتمال زیاد حاکی از اهمیت غلظت ترکیبات محیط کشت.
کلید واژگان: برگچه، ریزنمونه، زرد شدن، گیاه دارویی، هورمونThis research carried out to optimize the micro propagation of medicinal plants dog rose, one of the rose rootstock, for quick access to get suitable callus. A factorial experiment conducted based on a completely randomized design with two factors, medium (1/2 MS and 1/4 MS) and different concentrations of 2,4-D (0, 1, 2.5, 4, and 5.5 mgL-1 ), with four replications. Explants prepared from middle of axillary stem during the fruiting stage in 1.5 cm length with nodal. The results evaluated based on deformation (ready to enter the callus production phase) and callugenesis ability after one month of planting. Results showed that the highest percentage of explants deformation related to 1/2 MS. The highest percentage of deformation in the bud area, and head and whole explants related to four and 2.5 mgL-1 2,4-D concentration, respectively. In addition, the highest percentage of callugenesis observed in one and two sides of explants. The highest fresh and dry weight of callus obtained from the high peak of 2,4-D and 1/2 MS containing 2.5 mgL-1 2,4-D. Callus produce in meristematic regions of leaflets base that attached to the axis of the explants (along with yellowing leaves) was not only influenced by 2,4-D. But also, this probably related to the importance of the high concentrations of medium nutrition time of taking explants (relating on the internal hormone balance and the amount of stored carbohydrates).
Keywords: leaflets, explant, yellowing, medicinal plant, hormone -
گیاهان دارویی فراوانی در ایران هستند که می توانند مورد چرای دام قرار گیرند. با توجه به اطلاعات محدود در زمینه ارزش تغذیه ای برخی از این گیاهان، این مطالعه با هدف بررسی ترکیبات شیمیایی-معدنی، ظرفیت بافری و برخی فراسنجه های هضمی-تخمیری گونه های دارویی شامل درمنه کوهی (Artemisia aucheri Boiss)، مریم گلی (Salvia leriifolia Benth)، بومادران (Achilea santolina) و پونه سای انبوه (Nepeta glomerulosa Boiss) در شرایط برون تنی انجام شد. بیش ترین مقدار الیاف نامحلول در شوینده اسیدی (30/03 درصد)، الیاف نامحلول در شوینده خنثی (46/46 درصد)، لیگنین نامحلول در شوینده اسیدی (16/79 درصد) و فیبر خام (32/87 درصد) مربوط به پونه سای بود (0/05>p). بیش ترین مقدار پروتئین خام (22/19 درصد) و کربوهیدرات های غیر الیافی (36/96 درصد) در بومادران مشاهده شد (0/05>p). دامنه کلسیم از بیش ترین مقدار (44/06 گرم در هر کیلوگرم ماده خشک) برای مریم گلی تا کم ترین مقدار برای بومادران (4/39 گرم در هرکیلوگرم ماده خشک) متغیر بود. بومادران (48/04 میلی لیتر) و مریم گلی (39/72 میلی لیتر) به ترتیب بیش ترین مقدار پتانسیل تولید گاز را داشتند. بالاترین میزان قابلیت هضم ماده خشک (60 درصد) در بومادران مشاهده شد (0/05>p). دامنه انرژی قابل متابولیسم از 4/65 مگاژول در هر کیلوگرم ماده خشک برای درمنه کوهی تا 7/29 مگاژول در هر کیلوگرم ماده خشک برای بومادران متغیر بود. غلظت نیتروژن آمونیاکی محیط کشت (29/62-28/06 میلی گرم در هر دسی لیتر) تحت تاثیر تیمارهای آزمایشی قرار نگرفت. بالاترین pH گیاه (5/98) و ظرفیت بافری اسیدی (212/12 میلی اکی والان گرم×3-10) به ترتیب در گونه های درمنه کوهی و مریم گلی مشاهده شد (0/05>p). با توجه به نتایج موجود، بومادران از ارزش تغذیه ای بالاتری برخوردار بود.کلید واژگان: ارزش تغذیه ای، دام، گیاه دارویی، منبع علوفه ایThere are many medicinal plants in Iran that can be grazed by livestock. Due to lack of information about the nutritional value of some medicinal plants, this study aimed to investigate the chemical-mineral composition, buffering capacity and some digestive-fermentation parameters of medicinal species including Artemisia aucheri Boiss, Salvia leriifolia Benth, Achilea santolina and Nepeta glumerulosa by in vitro procedures. N. glumerulosa had the highest ADF (30.03%), NDF (46.46%), ADL (16.79%) and CF (32.87%) contents(p < 0.05). The highest crude protein (22.19%) and non-fiber carbohydrates (36.96%) were also related to A. santolina (p < 0.05). The calcium ranged from a high of 44.06 g/kgDM in S. leriifolia Benth to a low of 4.39 g/kgDM in A. santolina. The plants containing A. santolina (48.04 ml) and S. leriifolia Benth (39.72) also showed high potential gas production, respectively (p < 0.05). The highest dry matter digestibility (60%) belonged to A. santolina (p < 0.05). The range of metabolizable energy differed from 4.65 MJ/kg DM for A. aucheri Boiss to 7.29 MJ/kg DM for A. santolina. The ammonia nitrogen concentration (28.06-29.62 mg/dL) was not affected by the experimental treatments. The highest amount of pH (5.98) correlated to plant and acid-buffering capacity (212.12 mEq×10 -3 ) was observed in A. aucheri Boiss and S. leriifolia Benth species, respectively (p < 0.05). According to the available results, A. santolina had a higher nutritional value.Keywords: Forage source, livestock, Medicinal plant, Nutritional Value
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انجدان رومی با نام علمی Levisticum officinale گیاهی چند ساله از خانواده چتریان و متعلق به جنسی تک گونه ای است. این گیاه ارزشمند در ایران تنها در بخش کوچکی از رشته کوه های هزار در جنوب استان کرمان مشاهده می شود. جایگاه حفاظتی این گونه درقالب طرح تعیین جایگاه حفاظتی گیاهان و اکوسیستم های ایران، براساس شیوه نامه اتحادیه جهانی حفاظت از طبیعت (IUCN) و با استفاده از سه معیار میزان حضور، سطح تحت اشغال و اندازه جمعیت تعیین شد. نتایج نشان داد که گرچه این گونه در برخی کشورهای اروپایی کشت می شود، اما در ایران یه صورت وحشی و به شکل لکه های باریک و جدا از هم در رویشگاه دیده می شود و مساحت تحت اشغال آن 0/13 کیلومتر مربع است. براساس معیارهای جهانی حفاظت از طبیعت جایگاه این گونه در ایران در طبقه «در بحران انقراض (CR)» تعیین شد. بررسی ها نشان داد برداشت بی رویه و پیش از موعد گیاه و حشکسالی های اخیر از عوامل اصلی تهدید کننده این گیاه بشمار می روند.
کلید واژگان: جایگاه حفاظتی، کرمان، گیاه دارویی، Levisticum officinaleIran Nature, Volume:5 Issue: 3, 2020, PP 127 -133Levisticum officinale is a perennial herb, belonging to Apiaceae family. In Iran, this valuable species just grows in a small area of Hezar Mountains, located in South of Kerman province. Based on IUCN guidelines, three criteria were used to evaluate the status of this species: extent of occurrence (EOO), area of occupancy (AOO), and size of populations. Although this species is cultivated in some European countries, our results showed that it grows wild in the form of narrow and separate spots on the habitat, and its area of occupancy is 0.13 square kilometers in Iran. According to global standards for nature conservation and based on our results, Levisticum officinale is defined as a Critically Endangered (CR) species in Iran. The studies have shown that excessive exploitation, over-harvesting of young plants, and prolonged dry climate are the main threats to this species.
Keywords: Conservation status, Kerman, medicinal plant, Levisticum officinale -
International Journal of Advanced Biological and Biomedical Research, Volume:5 Issue: 3, Summer 2017, PP 149 -153Tribulus terrestris is a herbal remedy which is used for various purposes in folk medicine. It has been used as tonic, aphrodisiac, astringent, analgesic, stomachic, anti-hypertensive, diuretic and urinary anti-septic. It is about 30 to 70cm high; it grows as a summer annual, has pinnately compound leaves, yellow flowers and stellate shaped carpel fruits. Since the past decades, some plants have been playing important role in disease curing along with artificial medications commonly called medicinal plants. Some have compared the tonic properties of Tribulus terrestris to the effects of ginseng, but these occur due to entirely different mechanisms. It is also claimed that Tribulus terrestris increases testosterone by increasing gonadotropin releasing hormone (GnRH) which in turn stimulates the production of LH and follicle stimulating hormone (FSH). Testosterone, besides its role in muscle-building and raising fertility and libido, is also known to have a positive effect on bone marrow activity (for red blood cell production) and the immune systemKeywords: Tribulus terrestris, Medicinal plant, pharmaceutical effects
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International Journal of Advanced Biological and Biomedical Research, Volume:2 Issue: 2, Winter 2014, PP 823 -829Chamomile is a widely recognized herb in Western culture. Its medicinal usage dates back to antiquity where such notables as Hippocrates, Galen, and Asclepius made written reference to it. As part of any medication history, pediatricians always should ask a child’s caregiver about the child’s use of over-the-counter remedies and herbal products. Chamomile is used widely to treat children who have GI disorders such as colic, dyspepsia, and diarrhea and to treat skin conditions such as dermatitis. Clinical studies have demonstrated that chamomile may have a positive effect in the treatment of atopic dermatitis, colic, and diarrhea. There are few adverse effects in children. However, children who are allergic to ragweed, asters, and chrysanthemums should use chamomile with caution.Keywords: Chamomile (Matricaria recutita), Medicinal plant, Pharmaceutical effect
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International Journal of Advanced Biological and Biomedical Research, Volume:1 Issue: 10, Autumn 2013, PP 1289 -1295Tribulus terrestris is a herbal remedy which is used for various purposes in folk medicine. It has been used as tonic, aphrodisiac, astringent, analgesic, stomachic, anti-hypertensive, diuretic and urinary anti-septic. It is about 30 to 70cm high; it grows as a summer annual, has pinnately compound leaves, yellow flowers and stellate shaped carpel fruits. Since the past decades, some plants have been playing important role in disease curing along with artificial medications commonly called medicinal plants. Some have compared the tonic properties of Tribulus terrestris to the effects of ginseng, but these occur due to entirely different mechanisms. It is also claimed that Tribulus terrestris increases testosterone by increasing gonadotropin releasing hormone (GnRH) which in turn stimulates the production of LH and follicle stimulating hormone (FSH). Testosterone, besides its role in muscle-building and raising fertility and libido, is also known to have a positive effect on bone marrow activity (for red blood cell production) and the immune systemKeywords: Tribulus terrestris, Medicinal plant, pharmaceutical effects
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International Journal of Advanced Biological and Biomedical Research, Volume:1 Issue: 5, Spring 2013, PP 556 -562Tribulus terrestris is a herbal remedy which is used for various purposes in folk medicine. It has been used as tonic, aphrodisiac, astringent, analgesic, stomachic, anti-hypertensive, diuretic and urinary anti-septic. It is about 30 to 70cm high; it grows as a summer annual, has pinnately compound leaves, yellow flowers and stellate shaped carpel fruits. Since the past decades, some plants have been playing important role in disease curing along with artificial medications commonly called medicinal plants. Some have compared the tonic properties of Tribulus terrestris to the effects of ginseng, but these occur due to entirely different mechanisms. It is also claimed that Tribulus terrestris increases testosterone by increasing gonadotropin releasing hormone (GnRH) which in turn stimulates the production of LH and follicle stimulating hormone (FSH). Testosterone, besides its role in muscle-building and raising fertility and libido, is also known to have a positive effect on bone marrow activity (for red blood cell production) and the immune systemKeywords: Tribulus terrestris, Medicinal plant, pharmaceutical effects
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