بیماری ریفلاکس معده به مری

Inlet patch (IP) lesion is the presence of gastric columnar epithelial tissue outside of the stomach. Symptoms such as a lump in the throat, chronic cough, laryngitis, or other mouth-throat symptoms may be IP-related only and have no other abnormalities. This study aimed to determine the relationship between globus sensation and structural disorder of Inlet Patch in patients with gastroesophageal reflux disease

The case-control study was performed in patients who were referred to the endoscopy ward of Sina Hospital in Tehran from October 2016 to October 2017. Inclusion criteria were diagnosis of gastroesophageal reflux and endoscopic indications. Patients who had endoscopic indications and underwent endoscopy were evaluated. Information on reflux esophagitis and inlet patch structural disorder were determined. Symptoms of reflux, including a lump in the throat, were identified and recorded. Then the frequency of globus sensation in patients with inlet patch structural disorder (patient group) and without it (control group) was compared.

A total of 100 patients with gastric reflux participated in this study. Patients included 42 men (42%) and 58 women (58%). The mean age of patients was 41.17±10.35 years (18-77 years). The severity of mild reflux was 57%, moderate reflux was 27% and severe reflux was 16%. 28% of patients had a lump in the throat and 12 patients had an inlet patch. There was a statistically significant relationship between inlet patch and globus sensation (p=0.001). All patients with inlet patch had globus sensation. 81.8% of patients without inlet patch did not feel a lump in the throat. The results showed a statistically significant difference between the two groups with and without inlet patch in terms of globus sensation in general and in terms of different clinical variables (p=0.001).

The findings of the study showed that inlet patch had a significant relationship with the feeling of a lump in the throat and all patients with inlet patch felt Globus sensation.As the result, to diagnose a patient with an inlet patch, other causes such as esophagitis, hernia, heartburn and metabolic syndrome should be ruled out.

Background and Gastroesophageal reflux disease (GERD) is one of the most common chronic disorders of the digestive system. This survey was performed to determine the effect of Temperament–based dietary intervention on the symptoms of GERD.
In a randomized clinical trial, 60 patients with GERD attending the Qaem Hospital in Mashhad, Iran were randomly divided into nutrition education group (n= 30) and control group (n= 30). In case group, patients were referred to the Traditional Medicine Clinic and their temperament and dystemperament were verified by a traditional medicine physician. Temperament–based dietary education was held in intervention group for 1.5 hours according to the determined dystemperament. The participants were asked to follow the diet for two weeks. In control group, the same process was carried out along with the accustomed dietary education without taking notice to their temperament. The GERD questionnaire, food frequency questionnaire (FFQ), and 24-hour diet recalls (24-HDR) were administered to collect the data. SPSS V.11.5 was used to analyze the data applying Chi-square, Mann-Whitney, Independent T test, and Paired T test.
After the intervention, significant decrease were seen in the symptoms among the intervention group including heartburn (25.5%), frequency of acid regurgitation (14%), heartburn severity (11.3%), acid regurgitation severity (23.6%) and duration of heartburn (5.2%), duration of acid regurgitation (34%), and heartburn dissemination (8.8%) (P Considering temperament in diet can play an important role in improving the symptoms in patients with Gastroesophageal Reflux Disease.

Gastroesophageal reflux disease is one of the most common chronic disorders of the digestive system. Almost anyone experiences heartburn or reflux (the two main symptoms of the disease) in a situation. Nutritional changes education as the first step of nursing intervention is the easiest، cheapest and the safest treatment approach. The aim of this study was to determine the effect of Temperament–based diet education on Quality of Life in patients with GERD who was admitted to Qaem Hospital in city of Mashhad. This clinical trial was a pretest/posttest experimental design with control group. A sample of 60 patients with gastroesophageal reflux disease، who had admitted to Qaem hospital from 5th March 2013 to 20th June 2013، was divided into two groups by random assignment. After verifying the patient temperament، the intervention consisted of holding nutrition education classes in accordance with temperament for 1. 5 hours and accomplishing the diet as possible for two weeks. Research tools were GasroEsophageal Reflux Syndrome Health Related Quality of Life (GERD-HRQL) questionnaire and performing diet checklist. The data was analyzed by SPSS software version 11. 5 and by using Independent T test، Paired T test and ANOVA test. With respect to the higher score of this questionnaire، it was shown to be equal to the lower quality of life situation، comparison of the mean scores difference of quality of life. One-way ANOVA in both groups showed that quality of life scores in education group (8. 80 4. 22) was significantly lower than the quality of life scores in the control group (14. 53 5. 98) after an intervention (p<0. 0001). Considering temperament in the diet education by nurses can play an important role in increasing the quality of life in patients with Gastroesophageal Reflux Disease.