مرگ داخل رحمی

Zinc deficiency has been suggested as a risk factor for adverse pregnancy outcomes. Since dealing with zinc deficiency is an easy and inexpensive method, this study was conducted with the aim of investigating the relationship between adverse pregnancy outcomes and zinc concentration of amniotic fluid and maternal plasma in the second trimester and biomarkers of the first and second trimester.

This cross-sectional study was conducted on 102 pregnant mothers who were candidates for amniocentesis in Mousavi Hospital in Zanjan in 2018 through convenience sampling. Women with normal amniocentesis results were followed up until delivery in terms of adverse pregnancy outcomes (incidence of preeclampsia, intrauterine growth retardation, premature delivery, fetal death, and low birth weight) and were divided into two groups with adverse pregnancy outcomes (first group) and without adverse pregnancy outcomes (second group) and were compared in terms of zinc concentration in plasma and amniotic fluid.

The concentration of zinc in the plasma of the mothers of the first group (59.53±15.88 µg/dl) was significantly lower than that of the mothers of the second group (71.44±19.25 µg/dl) (p=0.02). However, there was no significant difference in the concentration of zinc in the amniotic fluid of the two study groups. In this study, the best cutoff point to determine people at risk of adverse pregnancy outcomes was determined to be 60.5 µg/dl.

Based on the results of this study, there seems to be a relationship between low zinc concentration of plasma in pregnant women and adverse outcomes.

Intra-uterine fetal death (IUFD) is a traumatic event for the family which occurs in about 1% of all pregnancies. In comparison with other countries this rate is increasing in Iran. Certainly many factors cause IUFD which include intra-uterine infection, lethal malformations, fetal growth retardation and placental abruption. The aim of this case-control study was to determine the risk factors of IUFD among our patients.Subjects and In this retrospective case-control study, which used a self-made quesitonaire designed to assess the risk factors associated with maternal or fetal factors for intrauterine deaths. The samples included 953 records (358 cases and 595 controls). The data were collected form patents records in Imam Khomeini hospital during a five year period of 2001-2006. We used a questionnaire which designed for assessement of maternal and fetal factors. The questionnaire was filled by using collected medical records. The estimated rate of IUFD was 4%. We found IUFD was related with older aged mother (P< 0.002), previous IUFD (P< 0.000), with Arab race) P = 0.000), Malformation (P <0.000), fetal weigh (P < 0.022), pregnancy complications (P< 0.025) and maternal diseases (P< 0.000). This study shows the rate of IUFD (4%) is increasing in Ahvaz. It is difficult to identify preventable factors of IUFD. However proper prenatal care consultation can facilitate early diagnosis may prevent complications and may reduce the incidence of IUFD.