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benign paroxysmal positional vertigo

در نشریات گروه پزشکی
  • Amirreza Fazelifard, Majid Ashrafi *
    Background and Aim

    Benign Paroxysmal Positional Vertigo (BPPV) impacts the quality of life of affected people, especially the elderly. The Epley maneuver and the Gans maneuver are used to treat Posterior Canal BPPV (PC-BPPV). The effectiveness of the Epley maneuver has been verified, but further studies are required to prove the effectiveness of the Gans maneuver. The main purpose of the current study was to compare the effectiveness of the Gans maneuver with the Epley maneuver in the treatment of the elderly with PC-BPPV, considering emotional, physical, and functional symptoms by assessing anxiety, dizziness, and quality of life after treatment.

    Methods

    Sixty-three elderly patient (74.38±5.34 years) with unilateral PC-BPPV were recruited in this study. They were randomly assigned to two groups. The experimental group received the Gans maneuver, and the control group received the Epley maneuver. All patients completed the Persian version of the Dizziness Handicap Inventory (DHI) and Vestibular Rehabilitation Benefit Questionnaire (VRBQ) before, 48 hours and 1 month after treatment. Recurrence rate was assessed after the 2-month follow up.

    Results

    Significant differences were observed between pre-treatment and post-treatment questionnaire outcomes for both study groups; nevertheless, in each phase of the study, there were no significant differences between the two groups in the DHI and VRBQ scores.

    Conclusion

    Both the Gans maneuver and Epley maneuver were almost equally effective and made elderly with PC-BPPV report a better condition in terms of anxiety, emotional factors and quality of life after receiving the maneuvers.

    Keywords: Benign Paroxysmal Positional Vertigo, Epley Maneuver, Gans Repositioningmaneuver
  • Maliheh Akbarpour, Mir Mohammad Jalali, Nafiseh Sadeghzadeh
    Background and Aim

    Magnesium is essential for the morphogenesis of otoconia. The imbalance in the chemical composition of otoconia can make people susceptible to Benign Paroxysmal Positional Vertigo (BPPV). The primary outcome was to compare serum magnesium levels in BPPV patients with controls. The Ca/Mg ratios in participants are also recorded and analyzed in the present study.

    Methods

    In this case-control study, we measured the serum Mg, Ca, and vitamin D in BPPV patients and age-, sex-matched subjects without BPPV. The results were adjusted for Ca, vitamin D, hypertension, and body mass index.

    Results

    A total of 123 BPPV patients participated in this study. The mean Mg value was higher in patients than controls (2.01 vs. 1.95 mg/dL, p=0.030). Condition logistic regression analyses showed a higher rate of BPPV among subjects with low Ca/Mg ratio (quartile 1), relative to subjects with medium ratio (quartiles 2 and 3) (adjusted OR: 3.92, p=0.003).

    Conclusion

    The present study demonstrated an imbalance of Ca and Mg in the BPPV patients as significantly higher Mg levels and lower serum Ca/Mg ratio. Although it appears decreased Ca/Mg ratio to be a risk factor for BPPV, this result should be confirmed in confirmatory studies.

    Keywords: Magnesium, calcium, benign paroxysmal positional vertigo, otolithic membrane, matched-pair analysis
  • Adel Imani, Mahdi Khajavi, Amir Hossain Ghazizadeh Hashemi, Narges Bazgir, Farzin Davodi, Mohammadsmaeil Kordjazi, Mahya Mohammadi
    Background

     Benign paroxysmal positional vertigo (BPV) is the most common cause of the high prevalence of vertigo. Today, BPV is caused by the separation of autochthonous particles from the macular atrial. As a result, these particles float in a semicircular canal and change position by gravity. The majority of vertigo causes arise from the inner ear.

    Aim

     This study aims to measure the vitamin D level in patients with BPPV who visited Loghman Hakim Hospital clinics and compare the results with controls.

    Methods

     This comparative study evaluated the effect of vitamin D on reducing BPV. Demographic information of patients was collected through interviews. The physical examinations were recorded through a questionnaire. For the group with BPPV, we did the Epley maneuver and measured the vitamin D level. We compared the vitamin D levels of these patients with the matched control group.

    Results

     In this study, 148 patients were evaluated. Sixty-three patients were male, and 85 patients were female. All case and control patients were tested for vitamin D levels. Of 93 patients with benign vertigo, 39 (41.9%) patients had normal vitamin D levels, and 54(58.1%) patients had below normal. In the control group, 43 (78.2%) patients had normal vitamin D, and 12 (21.8%) patients had less than normal. There was a statistically significant difference between the two groups.

    Conclusion

     The present study indicated that BPV was more prevalent in people with vitamin D deficiency, and vitamin D treatment could effectively control and reduce the prevalence of this disease.

    Keywords: Vitamin D, Serum Levels, Benign Paroxysmal Positional Vertigo
  • Ali Sertac Yetiser *, Ziya Salturk
    Introduction

    Benign paroxysmal positional vertigo (BPPV) is a common cause of peripheral vestibular disturbances. Particle repositioning or liberatory maneuvers provide relief of symptoms in the majority of patients. However, studies mainly focus on success. This study aims to review the conditions that may have an impact on residual dizziness or recurrence following therapeutic maneuvers in patients with BPPV. 

    Materials and Methods

    A review of the literature about the analysis of quality of life after therapeutic maneuvers was conducted. Three hundred and seven articles after search in the PubMed database were classified into eight main groups after exclusion of those that are not suitable to predetermined criteria. 

    Results

    Thirty-eight articles for residual dizziness in BPPV, eighty-three articles for the duration of BPPV, forty articles for the type of canal involvement, forty-three articles for the impact of age, one hundred and nine articles for the gender difference, forty-seven articles for co-morbid conditions, one hundred and twenty-four articles for medication and sixty-eight articles for vestibular exercises in BPPV were selected. 

    Conclusion

    VEMP abnormality is a reliable indicator to demonstrate the risk of recurrence. Duration of dizziness has no significant impact on recurrence. But the length of duration is important for residual dizziness. Vestibular rehabilitation or medication alone has no place in treatment but may help to reduce the symptoms in addition to maneuver. Self-perceived evaluation of balance after therapeutic maneuvers is recommended for the selection of those who need rehabilitation or additional medication.

    Keywords: Benign paroxysmal positional vertigo, Balance, Quality of life, Residual dizziness, Recurrence
  • Wei Ta HUANG, Hung Jung LIN*, I Jung FENG, Chien Chin HSU, Jhi Joung WANG, Chien Cheng HUANG, Shih Bin SU
    Background

    Because of the limited information available regarding peripheral vertigo (PV) in physicians, we conducted this study to clarify this issue.

    Methods

    We used Taiwan National Health Insurance Research Database to identify 26,309 physicians and an identical number of general population matched by age and sex. All the participants who had PV before 2007 and residents were excluded. By tracing their medical histories between 2007 and 2013, comparisons of PV risk between physicians and general population and among physicians were performed.

    Results

    Physicians had a significantly lower PV risk than the general population (adjusted odds ratio [AOR]: 0.811; 95% confidence interval [CI]: 0.662–0.994). In comparison among physicians, otolaryngologists had a significantly higher PV risk than other specialties. Physicians who were older or served in local hospitals or clinics had a significantly higher PV risk than physicians in medical centers.

    Conclusion

    Physicians had a significantly lower PV risk than the general population. Better medical knowledge in physicians than in the general population may explain the findings; however, further studies are warranted for elucidating the detailed mechanisms.

    Keywords: Benign paroxysmal positional vertigo, Peripheral vertigo, Physician
  • Shyh Poh TeO*
    Introduction

    To identify the type of referrals received by vestibular physiotherapists for vertigo and assess whether medical review for these patients would be appropriate.

    Materials and Methods

    We performed a retrospective review of referral forms, vestibular assessment forms, and vertigo clinic letters of patients referred for vertigo or vestibular physiotherapy input between July 1, 2013, to December 31, 2013.

    Results

    We studied 29 patients with a median age of 63 years. A diagnosis was provided in 65.5% of the referrals. Of 14 patients with possible benign paroxysmal positional vertigo (BPPV), Dix-Hallpike had been performed only for 4 patients. Almost half were seen for the medical review in the Vertigo Clinic due to the concerns of possible alternative non-vestibular diagnosis, medication issues, or syncope. Alternative diagnoses identified medically included orthostatic hypotension, stroke, vestibular migraine, medication-induced bradycardia, and phobic postural vertigo. Medication changes in vertigo clinic included treatment for heart failure, migraine, and medication optimization.

    Conclusion

    Medical review is appropriate for some patients referred for vestibular physiotherapy. A medical opinion should be sought by vestibular physiotherapists if there is uncertainty or concerns that the referred patients did not have straightforward vestibular problems, or there were possible alternative diagnoses, concerns with medications, or syncope.

    Keywords: Vestibular physiotherapy, Vertigo, Dizziness, Benign paroxysmal positional vertigo
  • محسن احدی*، نیما رضازاده، الهه مشرف
    سابقه و هدف

     سرگیجه وضعیتی حمله ای خوش خیم (BPPV: Benign Paroxysmal Positional Vertigo) شایع ترین عامل ابتلا به سرگیجه های حاد محیطی است که اغلب نشانه های سایکولوژیک آن نادیده گرفته می شود. در این راستا، مطالعه حاضر با هدف بررسی ارتباط تاثیرات سرگیجه وضعیتی حمله ای خوش خیم بر حافظه شنوایی- کلامی مبتلایان انجام شد.

    مواد و روش ها

    در این مطالعه مقطعی در مجموع 40 فرد مبتلا به سرگیجه حاد تحت آزمایشات شنوایی و وستیبولار قرار گرفتند و پس از تشخیص ابتلا به سرگیجه وضعیتی حمله ای خوش خیم، نسخه فارسی پرسشنامه سنجش معلولیت ناشی از گیجی و آزمون حافظه شنوایی- کلامی ری برای آن ها اجرا شد.

    یافته ها

    نتایج نشان دادند که میزان معلولیت ناشی از سرگیجه وضعیتی حمله ای خوش خیم موجب کاهش ظرفیت حافظه شنوایی- کلامی نسبت به افراد هنجار می گردد.

    نتیجه گیری

     مبتلایان به سرگیجه وضعیتی حمله ای خوش خیم که از سرگیجه های شدید چرخشی رنج می برند، نسبت به افراد هنجار دچار مشکلات بیشتری در یادگیری از طریق حافظه شنوایی- کلامی هستند و ابتلا به سرگیجه حاد به عنوان یک حالت ناخوشایند جسمی می تواند منجر به عوارض شناختی قابل ملاحظه ای در آن ها گردد.

    Mohsen Ahadi*, Nima Rezazadeh, Elahe Mosharaf
    Background and Objective

    Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo with peripheral origin, and its psychologic consequences frequently ignored by clinicians. In this regard, the present study aimed to investigate the effects of BPPV on patient auditory-verbal memory.

    Materials and Methods

    In this cross-sectional study, a total of 40 volunteer patients with acute vertigo underwent auditory and vestibular function tests. In addition, after the confirmation of BPPV, the Persian version of Dizziness Handicap Inventory was completed by all the subjects. Then, the Persian version of the Rey Auditory-Verbal Learning Test was conducted on the participants.

    Results

    The obtained results showed that the level of disability caused by BPPV could lead to a decrease in the capacity of auditory-verbal memory in comparison to that in normal individuals.

    Conclusion

    Patients with BPPV who suffer from severe rotator vertigo have higher number of problems in learning through auditory-verbal memory in comparison to normal individuals. Moreover, suffering from acute vertigo as an unpleasant physical condition can lead to considerable cognitive consequences in these patients.

    Keywords: Auditory-Verbal Memory, Benign Paroxysmal Positional Vertigo, Learning
  • Nuan Wang, Hao Zhou, Hongli Huang, Deqin Geng, Xiuhua Yang, Chunyu Yu, Di Shi
    Background
    We determined the diagnostic and therapeutic effects of SRM-IV vestibular function diagnosis and treatment system on benign paroxysmal positional vertigo (BPPV).
    Methods
    Overall, 120 patients with BPPV diagnosed in the outpatient and in-patient departments of the Vertigo Treatment Center of the First People's Hospital of Xuzhou from January 2013 to December 2015 were selected for this study. They were randomly divided into three groups. Automatic repositioning procedure was conducted for 40 patients in the equipment repositioning group by SRM-IV vestibular function diagnosis and treatment system, conventional manual repositioning procedure was used for 40 patients in the manual repositioning group, and combination of treatment drugs (alprostadil and safflower injection) with acclimatization training was adopted in 40 patients in the drug therapy group.
    Results
    After 1 week of treatment, the cure rate and total effective rate in the equipment repositioning group and the manual repositioning group were significantly higher than those in drug therapy group (P
    Conclusion
    The SRM-IV vestibular function diagnosis and treatment system are helpful in achieving effective and standard diagnosis and treatment of BPPV.
    Keywords: SRM-IV vestibular function, Benign paroxysmal positional vertigo, Automatic repositioning
  • Yones Lotfi, Mohanna Javanbakht, Maryam Sayaf, Enayatollah Bakhshi
    Background And Aim
    Benign paroxysmal positional vertigo (BPPV) is most common type of vertigo in general population. Epley maneuver is the most effective treatment technique. However, there is no clinically valid test to verify effectiveness of maneuver quickly after treatment in the same session. Modified clinical test of sensory interaction on balance (mCTSIB) is considered as a quick and simple test. This study aimed to use mCTSIB for assessing effectiveness of Epley maneuver in BPPV patients.
    Methods
    The study was carried out on 44 patients (36 female and 8 male, mean age of 53.11 (SD=7.09) diagnosed with posterior semicircular canals BPPV in Dix-Hallpike test and no other vestibular disorders. mCTSIB in four conditions was assessed, before and after Epley maneuver. Balance time, lateral and anterior-posterior sway were recorded. mCTSIB repeated after three weeks to assess reliability.
    Results
    The time for balance control in mCTSIB after maneuver did not change significantly relative to before maneuver (p>0.05). Lateral sway changes in conditions 2, 3 and 4 in mCTSIB significantly reduced after maneuver (p=0.04). Anterior-posterior sway changes in conditions 1 and 2 showed no significant difference after maneuver, however, differences in conditions 3 and 4 were statistically significant (p
    Conclusion
    mCTSIB is seems be a valid test with simple and quick apply for verifying the effectiveness of Epley maneuver in BPPV patients.
    Keywords: Benign paroxysmal positional vertigo, Epley, postural control
  • Tayyebe Fallahnezhad, Mansoureh Adel Ghahraman *, Saeid Farahani, Reza Hoseinabadi, Shohreh Jalaie
    Introduction
    Benign paroxysmal positional vertigo (BPPV), involving the semicircular canals, is one of the most common diseases of the inner ear. The video head impulse test (vHIT) is a new test that examines the function of the canals. This study aimed to investigate the vestibulo-ocular reflex (VOR) gain, gain asymmetry and saccades after stimulating all six canals in patients definitively diagnosed with posterior semicircular canal BPPV (PSC-BPPV).
    Materials And Methods
    Twenty-nine unilateral PSC-BPPV patients with normal oculographic and caloric results were enrolled in this study. vHIT was performed on six canals, and VOR gain, gain asymmetry and saccades were measured.
    Results
    Sixteen (55.17%) patients had abnormal posterior canal VOR gains in the ipsilesional ear. VOR gains in both horizontal canals were within normal limits. Superior canal VOR gains were mostly lower than normal and were not correlated to PSC abnormalities (P>0.05). No corrective saccades could be observed.
    Conclusion
    VOR gain in the direction of the posterior semicircular canal may be reduced in PSC-BPPV patients. Evaluation of PSC-VOR parameters could be beneficial, although superior canal measurements should be interpreted with caution.
    Keywords: Benign paroxysmal positional vertigo, Head impulse test, Semicircular canals, Vestibulo-ocular reflex
  • Mahboobeh Sheikhzadeh, Yones Lotfi, Abdollah Mousavi, Behzad Heidari, Mohsen Monadi, Enayatollah Bakhshi
    Background
    Benign paroxysmal positional vertigo (BPPV) is linked to vitamin D deficiency. This clinical trial aimed to determine the influence of vitamin D supplementation on intensity of BPPV.
    Methods
    The study population was selected consecutively and the diagnosis of BPPV was made by history and clinical examination and exclusion of other conditions. Intensity of BPVV was assessed based on VAS score (0-10). Serum 25-hydroxyvitamin D (25-OHD) was measured using ELISA method and levels
    Results
    After two months of treatment, in both vitamin D treated and non-treated groups the intensity of BPPV decreased significantly as compared with control (P=0.001 for both groups) but at endpoint, the intensity of BPPV aggravated and regressed to the baseline value in vitamin D deficient non-treated group (P=0.001) whereas, in vitamin D treated group, improvement of BPPV remained stable and unchanged over the study period.
    Conclusion
    This study indicates that correction of vitamin D deficiency in BPPV provides additional benefit to rehabilitation therapy (Epley maneuver) regarding duration of improvement. These findings suggest serum 25-OHD measurement in recurrent BPPV.
    Keywords: Benign paroxysmal positional vertigo, Intensity, Vitamin D, Rehabilitation Therapy
  • Motasaddi, Zarandi Masoud, Nemati Shadman*, Panahi Rasoul, Akbari Maryam
    Background
    Meniere’s disease (MD) is a chronic illness defined as an idiopathic syndrome of endolymphatic hydrops. Benign paroxysmal positional vertigo (BPPV) is a balance disorder and can be the sequel of diverse inner ear impairments.
    Objectives
    The purpose of this study was to investigate the prevalence of BPPV in MD patients.
    Materials And Methods
    All patients with definite or probable MD participated in this cross-sectional descriptive and analytic study between March 2013 and February 2014. We used the American Academy of Otolaryngology–Head and Neck Surgery (AAO-HNS) criteria plus electrocochleography (ECochG) test results to define the presence of MD and positional tests to determine the presence of BPPV. The frequency was reported. Independent sample t-test was also used in SPSS19.
    Results
    A total of 39 patients (43 ears) with definite or probable MD (26 female, 13 male; mean age: 46.4 ± 9.2 years) were enrolled in this study. Six out of 39 cases (15.4%) had BPPV in the posterior semicircular canal. The mean duration of MD was 28.5 months in BPPV group and 13.2 months in the non-BPPV group. Regardless of the age of the patients, there was a significant difference (p = 0.02) between the duration of MD in the two groups.
    Conclusions
    It seems that MD and BPPV are related and a longer duration of MD may result in a greater risk of developing BPPV.
    Keywords: Meniere Disease, Benign Paroxysmal Positional Vertigo
  • مژگان معصوم، منصوره عادل قهرمان*، عبدالرضا شیبانی زاده، کامران برین، شهره جلایی
    زمینه و هدف
    از آنجا که اتریکول اصلی ترین اندام های آسیب دیده در سرگیجه وضعیتی ناگهانی خوش خیم است به نظر می رسد ثبت پتانسیل برانگیخته دهلیزی چشمی روش مناسبی برای ارزیابی اختلال عملکرد اتریکول و تاثیر عودکنندگی این نوع سرگیجه باشد. از این رو، این مطالعه با هدف بررسی پارامترهای این آزمون در مبتلایان به سرگیجه وضعیتی ناگهانی خوش خیم انجام شد.
    روش بررسی
    در این مطالعه مقطعی، پتانسیل عضلانی با ارائه محرک تن برست 500 هرتز با شدت 95 دسی بل nHL از طریق راه هوایی در 25 فرد سالم و 20 فرد مبتلا به سرگیجه وضعیتی ناگهانی خوش خیم ثبت شد.
    یافته ها
    میانگین دامنه پاسخ در گوش مبتلا در مقایسه با گوش غیرمبتلا و افراد سالم کمتر و میانگین آستانه در گوش مبتلا نسبت به گوش غیرمبتلا و افراد سالم بیشتر بود(p<0/05). میانگین نسبت عدم تقارن دامنه در بیماران نسبت به افراد سالم بیشتر بود(p<0/001). دو گروه تفاوت معنی داری را از لحاظ میانگین زمان نهفتگی موج n10 و موج p15 نشان ندادند(p>0/05). تعداد ناهنجاری های پاسخ در گوش مبتلای بیماران بیشتر از گوش غیرمبتلا و گروه سالم بود(p<0/05). بیماران مبتلا به سرگیجه وضعیتی ناگهانی خوش خیم عودکننده نسبت به بیماران غیرعودکننده تعداد ناهنجاری بیشتری نشان دادند(p=0/03).
    نتیجه گیری
    نتایج پتانسیل عضلانی چشمی نشان دهنده اختلال بیشتر اتریکول در سرگیجه وضعیتی ناگهانی خوش خیم عودکننده است. پیشنهاد می شود از این آزمون در ارزیابی این نوع بیماران استفاده شود.
    کلید واژگان: پتانسیل عضلانی برانگیخته دهلیزی چشمی، اتریکول، اتولیت، سرگیجه وضعیتی ناگهانی خوش خیم
    Mozhgan Masoom, Mansoureh Adel Ghahraman, Abdolreza Sheybaniezadeh, Kamran Barin, Shohreh Jalaie
    Background And Aim
    Since utricle is the main damaged organ in benign paroxysmal positional vertigo (BPPV), ocular vestibular evoked myogenic potential (oVEMP) may be an appropriate method to evaluate the utricule dysfunction and the effect of disease recurrence rate on it. This study aimed to record myogenic potential in patients with benign paroxysmal positional vertigo.
    Methods
    In a cross-sectional study, ocular myogenic potential was recorded in 25 healthy subjects and 20 patients with benign paroxysmal positional vertigo using 500 Hz-tone bursts (95 dB nHL).
    Results
    In the affected ear, mean amplitude was lower and mean threshold was higher than those in the unaffected ear and in the normal group (p<0.05). Mean amplitude asymmetry ratio of patients was more than the healthy subjects (p<0.001). There was no statistical difference between the two groups regarding mean latencies of n10 and p15 (p>0.05). Frequencies of abnormal responses in the affected ears were higher than in unaffected ears and in the normal group (p<0.05). Furthermore, the patients with recurrent vertigo showed more abnormalities than the patients with non-recurrent (p=0.030).
    Conclusion
    In the recurrent benign paroxysmal positional vertigo, ocular vestibular evoked myogenic potential showed more damage in the utricle, suggesting this response could be used to evaluate the patients with benign paroxysmal positional vertigo.
    Keywords: Ocular vestibular evoked myogenic potential, utricule, otolith, benign paroxysmal positional vertigo
  • Fahimeh Hajiabolhassan, Elham Tavanai
    Benign Paroxysmal Positional Vertigo (BPPV) is a condition that indicates a benign inner ear disorder. It is generally believed that BPPV is due to the dislodged otoconial particles from otolith organs and unusual collection of them within any of semicircular canals or even in all three semicircular canals. Although the typical features of nystagmus in BPPV have been well-studied, very few studies (just four articles) have highlighted the presence of spontaneous nystagmus in BPPV recently. During the past 10 years, 2850 patients have been examined at the audiology unit of our department, and 254 patients have received diagnoses of BPPV but recently 2 patients presented with BPPV and spontaneous nystagmus, a new symptom that has been never observed in our clinical records. We herein describe this rare symptom in 2 case of BPPV. A 50-year-old woman with BPPV who showed an 18 degree spontaneous nystagmus treated with Epley maneuver and a 53-year-old man with 3 degree spontaneous nystagmus.
    Keywords: Benign Paroxysmal Positional Vertigo, Horizontal canal BPPV, Spontaneous nystagmus
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