control groups
در نشریات گروه پزشکی-
Background
The demand for orthodontic treatment to correct malocclusion has increased worldwide. A main cause of applying for orthodontics treatment may arise from mental disorders, such as Body Dysmorphic Disorder (BDD). This study aimed to investigate the relationship between BDD, the real need for orthodontic treatment based on the ICON index, and inquiry about orthodontics treatment in women.
MethodsIn a case-control study, 414 women from the public outpatient dental clinic of Mashhad University of Medical Sciences, completed a demographic questionnaire, Beck Depression Inventory (BDI II), Beck Anxiety Inventory (BAI), and Yale-Brown Obsessive-Compulsive Scale Modified for BDD (BDD-YBOCS). A specialist also determined the ICON index for each participant.
ResultsAmong 414 subjects, 52 patients (31 in the orthodontics and 21 in the control group) (p=0.182) had a BDD-YBOCS score of 20 or above. The frequency of BDD, based on a definite diagnosis by an interview with a psychiatric specialist, was 6.28% among the orthodontic patients, which was significantly more than that of other dental patients (p<0.05). The mean ICON index score was found to have a significant difference between the orthodontic patients and the controls (p<0.001). No correlation was found between the severity of ICON and BDD-YBOCS scores in all the participants (p=0.804), in the cases (p=0.655), or the controls (p=0.403).
ConclusionThe current study found no correlation between ICON and BDD score. However, a significantly higher rate of BDD subjects receiving orthodontic procedures suggests using the BDD-YBOCS survey in dental clinics to screen patients suspected of having BDD for further psychological management.
Keywords: Anxiety, Body Dysmorphic Disorder, Control Groups, Depression, Malocclusion, Outpatients -
AbstractBackgroundUsing an effective method to enhance nurses’ knowledge of ECG interpretation is one of the most essential requirements for nursing managers. Self-directed learning approaches can help to introduce lifelong learning in learners, especially in clinical settings. This study purposed to detect the effect of the implementation of the clinical teammate nurse program on the critical care nurses’ knowledge of ECG interpretation on cardiac arrhythmia.MethodsA pilot study was performed by a quasi-experimental design with a nonequivalent control group. The participants were 32 critical care nurses divided into two groups: the clinical teammate nurse program and control groups. The data were collected by a knowledge assessment questionnaire that measured nurses’ knowledge of ECG interpretation of cardiac arrhythmia. The nurses’ knowledge was measured three times: initial study, one month, and six months later.ResultsThe mean and standard deviation of age of participants was 32.38±7.03 years. There was a significant difference between three scores of repeated measurement of nurses’ knowledge (p<0.001), as the nurses’ knowledge one month after the study was significantly higher than in the initial test six months later. Also, pairwise comparisons showed that nurses in the clinical teammate program had higher knowledge scores than the control group (p<0.001).ConclusionThe clinical teammate nurse program can be used as an easy and economical way to improve nurses’ knowledge in interpreting ECG. This method can also be an excellent alternative to formal and traditional methods such as lecturing programs in continuing education programs.Keywords: Clinical Competence, Control Groups, Education, Con-Tinuing, Electrocardiography, Humans, Pilot Projects, Research Design, Surveys, Questionnaires
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Background
Tomatoes are fruits that are highly prone to spoilage, making them vulnerable to microbial decay. This research aimed to explore the effectiveness of an edible coating, specifically beeswax, in prolonging the shelf-life of tomato fruits.
MethodsA total of twenty-four tomatoes were procured from the market in September 2021, washed, and subsequently treated with beeswax at varying concentrations of 3, 6, 9, 12, and 15%) (w/v). The tomatoes were then stored in well-ventilated baskets for 30 days, during which organoleptic, biochemical, and microbial assessments were conducted. The Gas Chromatography-Mass Spectrometry analysis of the beeswax samples was performed following standard procedures. The relative percentage of each component was determined by comparing its average peak area to the total area. The mean and standard deviation of the duplicated data were calculated, and significance was assessed using ANOVA at a 95% confidence interval (p-value<0.05) with the aid of the Statgraphics Plus (version 5.0) statistical package.
ResultsThe beeswax emulsion achieved an optimal preservation rate of 70%, significantly higher than the control group, which had a rate of 20%. Additionally, a mean preservation rate of 68% was noted with the 12% beeswax emulsion, compared to 20% for control after 30 days. Fungal isolates identified from the fruits included Aspergillus niger, Candida krusei, Fusarium oxysporum, Candida sp., A. fumigatus, Penicillium notatum, and A. terreus. The Gas Chromatography-Mass Spectrometry analysis of the beeswax indicated the presence of certain compounds that may contribute to its antimicrobial properties.
ConclusionThe findings of this study demonstrate that beeswax emulsion effectively extends the shelf-life of tomato fruits, offering a potential solution to reduce waste and economic losses for farmers and the broader economy.
Keywords: Beeswax, Gas Chromatography-Mass Spectrometry, Control Groups, Emulsions, Edible Films -
Background
Despite significant advances in patient treatment, infection remains a complication after surgery. The present study compared the incidence and severity of wound infection with two methods of washing the primary prep area with 70% alcohol and normal saline in patients who are candidates for orthopedic surgery in Kowsar Hospital of Sanandaj, Iran.
MethodsThis single-blinded randomized clinical trial was conducted on 190 candidates for upper limb orthopedic surgery aged 18 to 65. Patients were randomly assigned to two alcohol and normal saline groups based on the table of random numbers. The primary outcome of this clinical trial was the incidence and severity of wound infection after surgery, which was measured by the standard scale of the Asepsis index. The results were analyzed using SPSS version 23, and statistical values less than 0.05 were considered significant.
ResultsPatients’ hospitalization duration in the intervention group was (3.02±1.04 days) and in the control group (2.86±1.03 days) showed no significant statistical difference (p=0.297). The frequency of wound infection in the alcohol group was lower than in the normal saline group. this difference was statistically significant (p=0.023). Also, the severity of wound infection in the 70% alcohol group (Mean=5.12, SD=3.19) was lower than in the normal saline group (Mean=7.69, SD=4.12). This difference was statistically significant (p<0.001).
ConclusionThe present clinical trial showed that the incidence and severity of wound infection after surgery were lower in the group washing the skin of the surgical area with alcohol compared to the group washing with normal saline.
Keywords: Acute Care Surgery, Asepsis, Chi-Square Distri-Bution, Control Groups, Ethanol, Hospitalization, Hospitals, Humans, Incidence, Orthopedic Procedures, Saline Solution, Upper, Extremity, Wound Infection -
مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران، سال هفتاد و پنجم شماره 6 (پیاپی 198، شهریور 1396)، صص 449 -456زمینه و هدفبروسلوز یک بیماری باکتریال مشترک بین انسان و دام می باشد. در بیماری بروسلوز، ایمنی هومورال و سلولی نقش اساسی دارند. با توجه به اینکه حجامت بر عملکرد سیستم ایمنی میزبان موثر است و توانایی نهفته در تنظیم واکنش های التهابی را دارد و به عنوان یکی از روش های درمانی مورد توجه در طب سنتی جهت درمان بیماری های التهابی به شمار می آید، از این رو هدف از انجام این مطالعه بررسی تاثیر حجامت بر سطح سرمی اینترفرون گاما (IFN-γ) در رت های آزمایشگاهی مبتلا به بیماری بروسلوز بود.روش بررسیاین پژوهش تجربی از فروردین 1394 تا شهریور 1394 در آزمایشگاه میکروب شناسی و حیوان خانه دانشگاه علوم پزشکی همدان به روش تجربی بر روی 48 سر رت در شش گروه انجام گرفت. ابتدا رت ها به روش تزریق داخل صفاقی با مقدار cfu/ml 105×5 از سویه بروسلا ملیتنسیس (Brucella melitensis) آلوده شدند. پس از گذشت یک هفته جهت اطمینان از صحت ابتلا رت های آلوده شده با بروسلا از تست های سرولوژی (رایت، کومبس رایت و 2-مرکاپتواتانول) (Wright، Coombs Wright، 2-Mercaptoethanol) جهت اثبات بیماری استفاده شد. سپس رت ها از ناحیه ساکرال حجامت شدند و پس از گذشت دو هفته سطح سرمی اینترفرون گاما با روش الیزا و مطالعه بافت ها با روش رنگ آمیزی هماتوکسیلین ائوزین مورد ارزیابی قرار گرفتند.یافته هایافته های این مطالعه نشان داد که حجامت باعث افزایش چشمگیری در میزان میانگین سطح سرمی اینترفرون گاما می گردد. در بررسی هیستوپاتولوژی بافت کبد رت ها در گروه های مبتلا شده به بروسلوز و حجامت شده، نشان از تاثیر حجامت بر بهبود ضایعات بافتی بود.نتیجه گیریاین مطالعه نشان داد که انجام حجامت می تواند باعث افزایش سطح سرمی اینترفرون گاما و در نتیجه کمک به پاکسازی بیماری و بهبود آسیب های حاصل بیماری بروسلوز گردد.کلید واژگان: بروسلوزیس، گروه کنترل، مرکاپتواتانول، اینترفرون گاما، رتBackgroundBrucellosis is a systemic infection caused by gram-negative coccobacilli and facultative intracellular bacteria of the genus brucella. Brucellosis is a bacterial disease common to humans and livestock. Infection with Brucella spp. continues to pose a human health risk globally despite strides in eradicating the disease from domestic animals. The humoral and cellular immunity plays an important role in brucellosis. The effect of phagocytosis and cellular immunity has been demonstrated in brucellosis. The effect of cupping as a therapeutic method on bacterial diseases has been demonstrated. By considering this fact that cupping is an effective method on host immune system functions and has potential effect to regulate the inflammatory reactions.MethodsThis experimental study was carried out on 48 rats in 6 groups (48 rats were divided into 6 groups) during the first 6 months from January 2015 to July 2016 in the laboratory of microbiology and animal of Hamedan University of Medical Sciences. The rats were infected through the injection of Brucella melitensis with plenty 5×105 (cfu/ml) of bacteria. After a week, in order to approve the accuracy of the infection in the studied rats inoculated with coombos Brucella melitensis, Wright test, 2-Mercaptoethanol test and Coomb's Wright test were used. The rats were then treated with cupping method in their sacral area. IFN-γ was measured using enzyme-linked immunosorbent assay. And the study of tissues using hematoxylin and eosin (H&E) Staining.ResultsThe results of this study showed that cupping leads to an increase in the mean serum level of interferon-gamma. The histopathological study of liver tissue showed that the radial arrangement was not observed in the infected group with brucellosis and the cells were acidophilus. While, the radial arrangement was observed in treated rats with cupping, but it was not complete. The number of enlarged sinusoids were reduced. But, cell infiltration was observed.ConclusionThis study showed that cupping can increase serum level of IFN-γ, and thus help to the clearance of disease and improvement of injury in the brucellosis animals lab.Keywords: brucellosis, control groups, interferon-gamma, mercaptoethanol, rats
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مقدمهآموزش با رویکرد حل مساله در حوزه پزشکی به عنوان رویکردی نو مورد پذیرش قرار گرفته و مطالعات نظری و تجریی زیادی صورت گرفته است. با وجود اهمیت این رویکرد، هنوز به روشنی اثربخشی آن به اثبات نرسیده است. این مطالعه با هدف بررسی میزان اثر بخشی آموزش با رویکرد حل مساله در حوزه آموزش پزشکی انجام گرفت.روش هااین پژوهش به شیوه مطالعه مداخله ای نیمه تجربی با طرح پیش آزمون-پس آزمون با گروه کنترل انجام گردید. جامعه مورد مطالعه دانشجویان رشته مدیریت خدمات بهداشتی درمانی سال تحصیلی 93-94 در درس مدیریت منابع انسانی دانشگاه علوم پزشکی شیراز بود. شیوه نمونه گیری مبتنی بر تعیین تصادفی یک کلاس به عنوان گروه آزمایش (21نفر) و یک کلاس به عنوان گروه گواه (19نفر) در نظر گرفته شد. جهت سنجش عملکرد تحصیلی دانشجویان از آزمون محقق ساخته استفاده گردید. داده ها با استفاده از آمار توصیفی (میانگین و انحراف معیار) و استنباطی (آزمون تحلیل کواریانس- ANCOVA) و از طریق نرم افزار آماریspss تجزیه و تحلیل شد.یافته هانتایج نشان داد که آموزش با رویکرد حل مسئله بر عملکرد تحصیلی دانشجویان به صورت معنی داری موثر است (01/0>p). با وجودی که میانگین نمرات دو گروه در پیش آزمون تفاوت چشم گیری با هم نداشتند با این حال میانگین گروه آزمایش در پایان دوره (پس آزمون) 16/33 و میانگین گروه گواه که 13/94 بوده که نشان از اثربخشی معنی دار رویکرد آموزش به شیوه حل مساله بر عملکرد تحصیلی دانشجویان داشت.نتیجه گیریبا توجه به اینکه آموزش به شیوه حل مساله بر موفقیت دانشجویان تاثیر مثبت و معنی داری دارد، توصیه می شود اساتید علوم پزشکی در بکارگیری از این شیوه تدریس مبادرت ورزند و آموزش به شیوه حل مساله در دستور دانشگاه های علوم پزشکی قرار گیرد.کلید واژگان: یادگیری حل مسئله، دانشجویان، آموزش، عملکرد تحصیلی، گروه کنترلIntroductionProblem-Based Learning is a new approach in medical sciences and some theoretical and experimental studies have been done in this regards. The purpose of this research is to investigate the effectiveness of PBL in medical sciences.MethodsThis is a quasi-experimental study with pretest-posttest design by control group. statistical population included 40 undergraduate students in Shiraz University of Medical Sciences (college of Management and Information) in course of Human Resources Development that were selected as random sampling method and divided into two groups of (Control group=19, and Experimental group=21). A man-made questionnaire was used for evaluating academic performance, data were analyzed using descriptive statistics (Mean and standard deviation) and inferential statistics (ANCOVA) through SPSS .Resultsresult showed that problem solving learning is effective on student's academic performance(pConclusionsince problem solving learning has a positive effect on student's performance, it is recommended medical sciences teachers try to use of this teaching approach and consider as priority in universities of medical sciences.Keywords: Problem-Based Learning, Students, Education, Academic Performance, Control Groups
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Event-related potential (ERP) is one of the most informative and dynamic methods of monitoring cognitive processes, which is widely used in clinical research to deal with a variety of psychiatric and neurological disorders such as attention-deficit/hyperactivity disorder (ADHD). In this study, there were 60 participants including 30 patients with ADHD and 30 subjects as a control group. Their ERP signals were recorded by three electrodes in two modalities. After a preprocessing step, several features such as band power, fractal dimension, autoregressive (AR) model coefficients and wavelet coefficients were extracted from recorded signals. The aim of this study is to achieve a high classification rate. The results show that the fractal dimensionwavelet combination features provided a good discriminative capability; it should be noted that this improvement was achieved by combining all sets of features and applying a feature selection algorithm, which resulted in a maximum accuracy rate of 88.77 and 95.39% in support vector machine (SVM) and v_SVM classification algorithms using a 10-fold cross-validation approach, respectively. ERP has been widely used for clinical diagnosis and cognitive processing deficits in children with ADHD. To increase the accuracy of the diagnostic process of ADHD, ERP signals were recorded to extract some specific ERP features related to this disease for classifying the two groups. The results show that the Fra-wave characterization produced the best average accuracy with an efficiency of 99.43% for v_SVM classifier, compared with 97.65% efficiency for the wavelet features and the other features.Keywords: Algorithms, attention, attention deficit disorder with hyperactivity child, cognition, cognition disorders, control groups, electrodes, evoked potentials, fractals, humans, nervous system diseases, support vector machine
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