جستجوی مقالات مرتبط با کلیدواژه « Threatened abortion » در نشریات گروه « پزشکی »

 A significant number of pregnancies are at risk of threatened abortion (TA). Different types of progesterone are used to treat TA.

 In this study, the effects of 2 forms of progesterone on the continuation of pregnancy and TA-caused pregnancy outcomes were compared.

 A total of 190 women with a gestational age of 6 - 13 weeks presenting with uterine bleeding, closed cervix, and absence of fetal heart rate diagnosed by vaginal examination and ultrasound were allocated into 2 groups and treated with either (D) dydrogesterone (10 mg twice a day) or (M) micronized progesterone (200 mg, twice a day) for beyond 2 weeks after the cessation of uterine bleeding to ensure that bleeding would not recur. The participants were followed up and received prenatal care until the end of pregnancy. The outcomes of pregnancy were recorded and compared between the 2 groups.

 The incidence of preeclampsia, gestational diabetes, cesarean section, intrauterine fetal death (IUFD), placenta previa, and abortion was not significantly different between the 2 groups. However, the prevalence of preterm labor and low birth weight (LBW) was significantly lower in M-treated women (P < 0.001 and P = 0.007, respectively). The baby’s weight and gestational age at delivery were significantly higher in the M group than in the D group (P < 0.001). No serious drug side effects were observed in the 2 groups throughout the study.

 The results of this study showed that the incidence of preterm labor and LBW was significantly lower in the patients treated with micronized progesterone than in patients treated with dydrogesterone; however, the prevalence of preeclampsia, gestational diabetes, cesarean section, IUFD, and abortion was not significantly different between the 2 groups.

 A significant number of pregnancies are at risk of threatened abortion (TA). Different types of progesterone are used to treat TA.

 In this study, the effects of 2 forms of progesterone on the continuation of pregnancy and TA-caused pregnancy outcomes were compared.

 A total of 190 women with a gestational age of 6 - 13 weeks presenting with uterine bleeding, closed cervix, and absence of fetal heart rate diagnosed by vaginal examination and ultrasound were allocated into 2 groups and treated with either (D) dydrogesterone (10 mg twice a day) or (M) micronized progesterone (200 mg, twice a day) for beyond 2 weeks after the cessation of uterine bleeding to ensure that bleeding would not recur. The participants were followed up and received prenatal care until the end of pregnancy. The outcomes of pregnancy were recorded and compared between the 2 groups.

 The incidence of preeclampsia, gestational diabetes, cesarean section, intrauterine fetal death (IUFD), placenta previa, and abortion was not significantly different between the 2 groups. However, the prevalence of preterm labor and low birth weight (LBW) was significantly lower in M-treated women (P < 0.001 and P = 0.007, respectively). The baby’s weight and gestational age at delivery were significantly higher in the M group than in the D group (P < 0.001). No serious drug side effects were observed in the 2 groups throughout the study.

 The results of this study showed that the incidence of preterm labor and LBW was significantly lower in the patients treated with micronized progesterone than in patients treated with dydrogesterone; however, the prevalence of preeclampsia, gestational diabetes, cesarean section, IUFD, and abortion was not significantly different between the 2 groups.

Threatened miscarriage is a common disorder in early pregnancy and is seen in 20% of pregnant women. Currently, there is no effective therapeutic solution for this condition. This study aimed to determine the effects of a special food (fried egg with grape molasses) on threatened miscarriage in combination with conventional therapies.

This randomized controlled clinical trial was conducted on 93 pregnant women with mild or moderate vaginal bleeding up to 16 weeks of gestation in two groups. The control group (n = 47) used progesterone 400 mg suppository daily with abstinence from sexual intercourse and physical activity. The intervention group (n = 46) consumed fried eggs with grape molasses and the routine treatment like the control group. The treatment was considered successful if the pregnancy continued up to 20 weeks. Finally, the risk of abortion (miscarriage rate) and the duration of vaginal bleeding were compared between two groups.

The risk of abortion in the control group was about 26% (12 of 45 pregnancies), while in the intervention group, it was 15% (7 of 45 pregnancies). This result was not statistically significant between the two groups (Risk ratio: 0.69, 95% CI: 0.37-1.30, P= 0.197). Additionally, no significant difference was detected regarding the duration of vaginal bleeding between the intervention and control groups (P= 0.699).

There is no significant statistical relationship between the consumption of “fried eggs with grape molasses” and reduction of abortion risk.

Determination of the best diagnostic methods for ectopic preg-nancy (EP) and threatened abortion is important specially to improve the final prognosis. The aim was to determine the CA-125 level in cases of EP and threatened abortion in comparison with control subjects.

In this descriptive cross-sectional study, 90 consec-utive women attending to Shohada-e-Tajrish and Mahdieh Hospitals in Teh-ran including those with EP and threatened abortion and control subjects were enrolled where CA-125 level was determined and compared across the three groups.

CA-125 level was significantly different across the groups (P<0.005) and in paired comparisons it was higher in threatened abortion cases versus control subjects (P<0.003). However, it was not significantly different between the other groups (P > 0.05).

Overall, it was found that the serum CA-125 level was higher in threatened abortion cases but not significantly in EP cases. Hence, use of this marker may be helpful in diagnosis of threatened abortion.

CA-125 is a glycoprotein and its origin is uncertain during pregnancy. It arises during the first trimester and return to a non-pregnancy range in late pregnancy.

The aim of this study was to compare CA-125 level in threatened abortion and normal pregnancy less than 20 weeks of pregnancy.

This was a prospective case study carried out on 50 healthy pregnant (group 1) and 50 threatened abortion women (group 2). We compared the levels of CA-125 in these groups and followed them to be informed of the outcome of pregnancy.

Fifty percent of women were in 20-24 years old group, primigravida and in the first trimester of pregnancy. The mean level of CA-125 in group 1 was 26.2 ± 3.25 IU/ml and in group 2 was 37.44 ± 2.72 IU/ml. The mean level of CA-125 in finally aborted patients was 58.17±7.25 IU/ml and in normal pregnant women, who continue to term, was 26.61±1.76 IU/ml. The CA-125 level in threatened women,whose pregnancy continued and did not abort, was 30.89 IU/ml. There was statistically significant difference between mean serum CA-125 levels of two groups (p < 0.05), while there was no statistically significant difference between these levels in the patients of both groups who continued pregnancies (p > 0.1). In group 2, there was a statistically significant difference in the level of CA-125 between those who developed abortion and those whose pregnancy continued but not aborted (p < 0.05).

Measurement of serum CA-125 may be an inexpensive, easily available, sensitive and specific predictor of outcome in threatened abortion, which results the loss of pregnancy.